PT2292231E - Agente terapêutico para a estenose do canal espinal - Google Patents

Agente terapêutico para a estenose do canal espinal Download PDF

Info

Publication number
PT2292231E
PT2292231E PT97701064T PT09770106T PT2292231E PT 2292231 E PT2292231 E PT 2292231E PT 97701064 T PT97701064 T PT 97701064T PT 09770106 T PT09770106 T PT 09770106T PT 2292231 E PT2292231 E PT 2292231E
Authority
PT
Portugal
Prior art keywords
therapeutic agent
spinal canal
canal stenosis
stenosis
spinal
Prior art date
Application number
PT97701064T
Other languages
English (en)
Inventor
Keiichi Kuwano
Original Assignee
Nippon Shinyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Shinyaku Co Ltd filed Critical Nippon Shinyaku Co Ltd
Publication of PT2292231E publication Critical patent/PT2292231E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965Non-condensed pyrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
PT97701064T 2008-06-23 2009-06-22 Agente terapêutico para a estenose do canal espinal PT2292231E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008162638 2008-06-23

Publications (1)

Publication Number Publication Date
PT2292231E true PT2292231E (pt) 2015-12-31

Family

ID=41444462

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97701064T PT2292231E (pt) 2008-06-23 2009-06-22 Agente terapêutico para a estenose do canal espinal

Country Status (15)

Country Link
US (1) US8629145B2 (pt)
EP (1) EP2292231B1 (pt)
JP (1) JP5527205B2 (pt)
KR (1) KR101626168B1 (pt)
CN (3) CN105168218A (pt)
CA (1) CA2728089C (pt)
CY (1) CY1117080T1 (pt)
DK (1) DK2292231T3 (pt)
ES (1) ES2557303T3 (pt)
HR (1) HRP20151443T1 (pt)
HU (1) HUE025885T2 (pt)
PL (1) PL2292231T3 (pt)
PT (1) PT2292231E (pt)
SI (1) SI2292231T1 (pt)
WO (1) WO2009157396A1 (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2246336T3 (da) * 2008-02-28 2020-07-20 Nippon Shinyaku Co Ltd Fibroseinhibitor
KR102705198B1 (ko) 2009-06-26 2024-09-11 니뽄 신야쿠 가부시키가이샤 결정
WO2011024874A1 (ja) * 2009-08-26 2011-03-03 日本新薬株式会社 塩基付加塩
AU2016366073B2 (en) 2015-12-02 2021-08-26 Nippon Shinyaku Co., Ltd. Pharmaceutical composition containing 2-{4-[N-(5,6- diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}-N- (methylsulfonyl)acetamide
CN109563055B (zh) * 2016-07-29 2021-12-24 成都苑东生物制药股份有限公司 氨基吡嗪类化合物或盐、异构体、其制备方法及用途
JOP20190204A1 (ar) 2017-03-08 2019-09-05 Actelion Pharmaceuticals Ltd تركيبة صيدلانية تشتمل على سيليكسيباغ
TWI801421B (zh) 2017-09-28 2023-05-11 日商日本新藥股份有限公司 結晶
US10407396B2 (en) * 2017-11-16 2019-09-10 Apotex Inc. Crystalline form of selexipag
BR112020008940A2 (pt) 2017-11-16 2020-10-20 Nippon Shinyaku Co., Ltd. preparação de liberação controlada
CA3154802A1 (en) 2019-10-23 2021-04-29 Marc Patrik SCHRADER Pharmaceutical composition comprising selexipag
WO2021152060A1 (en) 2020-01-31 2021-08-05 Actelion Pharmaceuticals Ltd Controlled release selexipag composition
TW202239408A (zh) 2021-01-29 2022-10-16 瑞士商艾克泰聯製藥有限公司 包含二苯基吡𠯤衍生物的醫藥組成物
TW202241425A (zh) 2021-01-29 2022-11-01 瑞士商艾克泰聯製藥有限公司 用於製造二苯基吡𠯤衍生物之程序
WO2022211052A1 (ja) * 2021-03-31 2022-10-06 日本新薬株式会社 歩行障害治療剤
JP7010404B1 (ja) 2021-03-31 2022-02-10 日本新薬株式会社 歩行障害治療剤
WO2023131608A1 (en) 2022-01-04 2023-07-13 Actelion Pharmaceuticals Ltd Controlled release compositions
WO2023214059A1 (en) 2022-05-06 2023-11-09 Actelion Pharmaceuticals Ltd Diphenylpyrazine compounds as prodrugs
WO2024017964A1 (en) 2022-07-20 2024-01-25 Actelion Pharmaceuticals Ltd Injectable pharmaceutical composition comprising a diphenylpyrazine derivative
WO2024133620A1 (en) 2022-12-22 2024-06-27 Actelion Pharmaceuticals Ltd In vitro dissolution test
WO2024194449A1 (en) 2023-03-23 2024-09-26 Actelion Pharmaceuticals Ltd Pharmaceutical composition comprising a diphenylpyrazine derivative

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI316055B (pt) 2001-04-26 2009-10-21 Nippon Shinyaku Co Ltd
WO2003070707A1 (fr) * 2002-02-19 2003-08-28 Ono Pharmaceutical Co., Ltd. Composes condenses derives de la pyridazine et medicaments contenant lesdits composes comme ingredients actifs
ES2584606T3 (es) * 2002-10-10 2016-09-28 Ono Pharmaceutical Co., Ltd. Microesferas que comprenden ONO-1301
DK2246336T3 (da) * 2008-02-28 2020-07-20 Nippon Shinyaku Co Ltd Fibroseinhibitor

Also Published As

Publication number Publication date
HRP20151443T1 (hr) 2016-01-29
PL2292231T3 (pl) 2016-03-31
US8629145B2 (en) 2014-01-14
SI2292231T1 (sl) 2016-03-31
JP5527205B2 (ja) 2014-06-18
ES2557303T3 (es) 2016-01-25
KR101626168B1 (ko) 2016-05-31
US20110105518A1 (en) 2011-05-05
JPWO2009157396A1 (ja) 2011-12-15
KR20110033125A (ko) 2011-03-30
DK2292231T3 (en) 2015-12-14
CA2728089A1 (en) 2009-12-30
CA2728089C (en) 2017-04-11
EP2292231A4 (en) 2012-03-28
HUE025885T2 (en) 2016-05-30
CN102065863A (zh) 2011-05-18
CY1117080T1 (el) 2017-04-05
EP2292231B1 (en) 2015-10-21
CN103690541A (zh) 2014-04-02
EP2292231A1 (en) 2011-03-09
CN105168218A (zh) 2015-12-23
WO2009157396A1 (ja) 2009-12-30

Similar Documents

Publication Publication Date Title
PL2292231T3 (pl) Środek terapeutyczny przeciw zwężeniu kanału kręgowego
HK1223262A1 (zh) 醫療器械
HK1206651A1 (en) Implant for tissue engineering
HK1205005A1 (en) Bone treatment systems
EP2308493A4 (en) ENHANCING OR THERAPEUTIC AGENT FOR DYSLIPIDEMIA
HK1137158A1 (en) Formulations for cancer treatment
HK1168749A1 (en) Medical apparatus
ZA201000013B (en) Medical implant
EP2189100A4 (en) MEDICAL DEVICE
ZA201001417B (en) Medical implant
GB0719608D0 (en) Medical Apparatus
EP2338457A4 (en) MEDICAL BED
EP2341852A4 (en) ORTHOPEDIC IMPLANT
EP2078536A4 (en) MEDICAL DEVICE
EP2127671A4 (en) THERAPEUTIC AGENT AGAINST CANCER
ZA200907492B (en) Compositions for targeted imaging and therapy
ZA201100697B (en) Orthopedic prosthesis
IL209006A0 (en) Therapeutic agent for male sterility
IL208664A0 (en) Conjugates for the treatment of mesothelioma
EP2236148A4 (en) MEDIinic agent for HELICOBACTER treatment
EP2140876A4 (en) THERAPEUTIC AGENT COMPRISING VASOHIBINE
GB0704334D0 (en) Patient bed
EP2127658A4 (en) THERAPEUTIC AGENT AGAINST MORBUS MENIERE
EP2210878A4 (en) THERAPEUTIC AGENT AGAINST TRPV1-MEDIATED DISEASES
GB0812940D0 (en) Medical implant