SI2234614T1 - Farmacevtska zmes za parenteralno administracijo ultra-kratko delujočega blokatorja beta-adrenoreceptorja - Google Patents

Farmacevtska zmes za parenteralno administracijo ultra-kratko delujočega blokatorja beta-adrenoreceptorja

Info

Publication number
SI2234614T1
SI2234614T1 SI200830850T SI200830850T SI2234614T1 SI 2234614 T1 SI2234614 T1 SI 2234614T1 SI 200830850 T SI200830850 T SI 200830850T SI 200830850 T SI200830850 T SI 200830850T SI 2234614 T1 SI2234614 T1 SI 2234614T1
Authority
SI
Slovenia
Prior art keywords
pharmaceutical composition
parenteral administration
acting beta
adrenoreceptor antagonist
ultrashort acting
Prior art date
Application number
SI200830850T
Other languages
English (en)
Inventor
Rudolf Stefan Widmann
Original Assignee
Aop Orphan Pharmaceuticals Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aop Orphan Pharmaceuticals Ag filed Critical Aop Orphan Pharmaceuticals Ag
Publication of SI2234614T1 publication Critical patent/SI2234614T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Emergency Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI200830850T 2007-12-21 2008-12-22 Farmacevtska zmes za parenteralno administracijo ultra-kratko delujočega blokatorja beta-adrenoreceptorja SI2234614T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT21072007 2007-12-21
PCT/AT2008/000470 WO2009079679A2 (de) 2007-12-21 2008-12-22 Pharmazeutische zusammensetzung
EP08863830A EP2234614B1 (de) 2007-12-21 2008-12-22 Pharmazeutische zusammensetzung zur parenteralen verabreichung eines ultrakurzwirksamen beta-adrenorezeptor antagonisten

Publications (1)

Publication Number Publication Date
SI2234614T1 true SI2234614T1 (sl) 2013-01-31

Family

ID=40634349

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200830850T SI2234614T1 (sl) 2007-12-21 2008-12-22 Farmacevtska zmes za parenteralno administracijo ultra-kratko delujočega blokatorja beta-adrenoreceptorja

Country Status (15)

Country Link
US (5) US20100311738A1 (sl)
EP (1) EP2234614B1 (sl)
JP (1) JP5623288B2 (sl)
CN (1) CN101903024A (sl)
AU (1) AU2008340179B2 (sl)
CA (1) CA2712414C (sl)
CY (1) CY1114951T1 (sl)
DK (1) DK2234614T3 (sl)
ES (1) ES2397126T3 (sl)
HR (1) HRP20121045T1 (sl)
NZ (1) NZ586200A (sl)
PL (1) PL2234614T3 (sl)
PT (1) PT2234614E (sl)
SI (1) SI2234614T1 (sl)
WO (1) WO2009079679A2 (sl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2872953C (en) 2012-05-10 2020-04-07 Aop Orphan Pharmaceuticals Ag Parenteral esmolol formulation
EP2796139A1 (en) * 2013-04-26 2014-10-29 AOP Orphan Pharmaceuticals AG Use of landiolol hydrochloride in the long-term treatment of tachyarrhythmias

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1985004580A1 (en) * 1984-04-09 1985-10-24 American Hospital Supply Corporation Pharmaceutical composition and method for treatment or prophylaxis of cardiac disorders
US4727064A (en) 1984-04-25 1988-02-23 The United States Of America As Represented By The Department Of Health And Human Services Pharmaceutical preparations containing cyclodextrin derivatives
US4857552A (en) 1988-06-08 1989-08-15 E. I. Du Pont De Nemours And Co. Stable pharmaceutical composition
DE4207922A1 (de) 1992-03-13 1993-09-23 Pharmatech Gmbh Wasserloesliche einschlussverbindungen und verfahren zu deren herstellung
CA2150554A1 (en) * 1992-12-02 1994-06-09 Sheng-Wan Tsao Cyclodextrin and polymer based drug delivery system
EP1239864A1 (en) 1999-11-23 2002-09-18 Aderis Pharmaceuticals, Inc. Treatment of heart rhythm disturbances with n6 -substituted-5'-(n-substituted) carboxamidoadenosines
TWI277414B (en) * 2001-01-12 2007-04-01 Baxter Int Esmolol formulation
WO2003028718A1 (en) * 2001-10-01 2003-04-10 Smithkline Beecham Corporation Novel formulations of carvedilol
WO2003033025A2 (en) 2001-10-18 2003-04-24 Decode Genetics Ehf Cyclodextrin complexes
JP2005530736A (ja) * 2002-04-18 2005-10-13 シーブイ・セラピューティクス・インコーポレイテッド ベーターブロッカー、カルシウムチャネルブロッカー、または心臓のグリコシドと共にa1アデノシンアゴニストを投与することを含む不整脈の処置方法
US7148211B2 (en) * 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
EP1417962A1 (de) 2002-11-06 2004-05-12 AOP Orphan Pharmaceuticals AG Verfahren zur Herstellung eines Arzneimittels enthaltend Esmolol
US7893040B2 (en) * 2005-07-22 2011-02-22 Oculis Ehf Cyclodextrin nanotechnology for ophthalmic drug delivery
CN1827109A (zh) * 2006-04-14 2006-09-06 北京润德康医药技术有限公司 一种以兰洛地尔及其盐为活性成分的冻干粉针制剂及其制备工艺
US8722736B2 (en) * 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol

Also Published As

Publication number Publication date
US20230277674A1 (en) 2023-09-07
WO2009079679A2 (de) 2009-07-02
US11517624B2 (en) 2022-12-06
ES2397126T3 (es) 2013-03-04
AU2008340179A1 (en) 2009-07-02
CA2712414A1 (en) 2009-07-02
US20200323988A1 (en) 2020-10-15
PL2234614T3 (pl) 2013-03-29
US20160361422A1 (en) 2016-12-15
US10660964B2 (en) 2020-05-26
CN101903024A (zh) 2010-12-01
US20190046646A1 (en) 2019-02-14
US20100311738A1 (en) 2010-12-09
HRP20121045T1 (hr) 2013-01-31
CY1114951T1 (el) 2016-12-14
JP2011506486A (ja) 2011-03-03
AU2008340179B2 (en) 2014-10-23
EP2234614A2 (de) 2010-10-06
CA2712414C (en) 2016-07-12
JP5623288B2 (ja) 2014-11-12
DK2234614T3 (da) 2013-02-11
EP2234614B1 (de) 2012-10-17
NZ586200A (en) 2012-06-29
PT2234614E (pt) 2013-01-25
WO2009079679A3 (de) 2009-11-26

Similar Documents

Publication Publication Date Title
HK1164059A1 (en) Compositions for drug administration
IL218928A (en) Corticosteroids for oral administration
ZA200807721B (en) Anti-cancer pharmaceutical composition
IL207512A0 (en) Pharmaceutical composition for poorly soluble drugs
IL194642A0 (en) Antagonist anti-cd40 antibody pharmaceutical compositions
HK1198287A1 (en) Pharmaceutical compositions comprising 2-oxo-1-pyrrolidine derivatives 2--1-
AP3542A (en) Anti-malarial pharmaceutical composition
HK1209649A1 (en) Pharmaceutical compositions comprising 2-oxo-1-pyrrolidine derivatives 2--1-
IL217927A (en) Azahetrocyclic compounds and their containing pharmaceutical preparations
ZA201105572B (en) Pharmaceutical composition for oral administration
IL195857A0 (en) Pharmaceutical compositions for treating psychological conditions comprising muscarinic receptor m1 antagonists
IL208325A0 (en) Stabilizing lipis compositions for oral pharmaceutical agents
HK1139052A1 (en) Composition for transdermal administration
PL2234614T3 (pl) Kompozycja farmaceutyczna do pozajelitowego podawania ultrakrótko działającego antagonisty receptora beta-adrenergicznego
IL196099A0 (en) Pharmaceutical composition for administration by injection
ZA201102405B (en) Pharmaceutical composition for oral administration
EP2520300A4 (en) PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION
PL2410997T3 (pl) Kompozycja do podawania polimerycznych leków