SI2217704T1 - Postopek za pospeševanje angiogeneze, vaskularizacije ali popravilo žil ali za zaviranje tumorske angiogeneze - Google Patents
Postopek za pospeševanje angiogeneze, vaskularizacije ali popravilo žil ali za zaviranje tumorske angiogenezeInfo
- Publication number
- SI2217704T1 SI2217704T1 SI200831774A SI200831774A SI2217704T1 SI 2217704 T1 SI2217704 T1 SI 2217704T1 SI 200831774 A SI200831774 A SI 200831774A SI 200831774 A SI200831774 A SI 200831774A SI 2217704 T1 SI2217704 T1 SI 2217704T1
- Authority
- SI
- Slovenia
- Prior art keywords
- angiogenesis
- vascularization
- promotion
- inhibition
- vascular repair
- Prior art date
Links
- 230000033115 angiogenesis Effects 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 230000005747 tumor angiogenesis Effects 0.000 title 1
- 230000002792 vascular Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/113—Antisense targeting other non-coding nucleic acids, e.g. antagomirs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/50—Methods for regulating/modulating their activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Plant Pathology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007052114A DE102007052114B4 (de) | 2007-10-30 | 2007-10-30 | Verfahren zur Modulation der Funktion, des Wachstums oder der Differenzierung einer Zelle |
| EP08844273.6A EP2217704B1 (de) | 2007-10-30 | 2008-10-30 | Verfahren zur förderung der angiogenese, vaskularisierung oder gefässreparatur oder zur hemmung der tumorangiogenese |
| PCT/DE2008/001759 WO2009056116A1 (de) | 2007-10-30 | 2008-10-30 | Verfahren zur förderung der angiogenese, vaskularisierung oder gefässreparatur oder zur hemmung der tumorangiogenese |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI2217704T1 true SI2217704T1 (sl) | 2017-05-31 |
Family
ID=40375407
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200831894T SI2684955T1 (en) | 2007-10-30 | 2008-10-30 | A method for promoting angiogenesis, vascular or repair of the vessels, or for inhibiting tumor angiogenesis |
| SI200831774A SI2217704T1 (sl) | 2007-10-30 | 2008-10-30 | Postopek za pospeševanje angiogeneze, vaskularizacije ali popravilo žil ali za zaviranje tumorske angiogeneze |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200831894T SI2684955T1 (en) | 2007-10-30 | 2008-10-30 | A method for promoting angiogenesis, vascular or repair of the vessels, or for inhibiting tumor angiogenesis |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US8258113B2 (https=) |
| EP (3) | EP2217704B1 (https=) |
| JP (4) | JP5898843B2 (https=) |
| CA (1) | CA2704290C (https=) |
| CY (2) | CY1120360T1 (https=) |
| DE (1) | DE102007052114B4 (https=) |
| DK (2) | DK2217704T3 (https=) |
| ES (2) | ES2618203T3 (https=) |
| HR (2) | HRP20170346T1 (https=) |
| HU (2) | HUE031559T2 (https=) |
| LT (2) | LT2684955T (https=) |
| NO (1) | NO2684955T3 (https=) |
| PL (2) | PL2217704T3 (https=) |
| PT (2) | PT2684955T (https=) |
| SI (2) | SI2684955T1 (https=) |
| WO (1) | WO2009056116A1 (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITRM20030376A1 (it) | 2003-07-31 | 2005-02-01 | Univ Roma | Procedimento per l'isolamento e l'espansione di cellule staminali cardiache da biopsia. |
| US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
| ES2911034T3 (es) | 2006-08-08 | 2022-05-17 | Univ Bonn Rheinische Friedrich Wilhelms | Estructura y uso de oligonucleótidos 5' fosfato |
| DE102007052114B4 (de) | 2007-10-30 | 2011-01-05 | T2Cure Gmbh | Verfahren zur Modulation der Funktion, des Wachstums oder der Differenzierung einer Zelle |
| WO2009141146A1 (en) | 2008-05-21 | 2009-11-26 | Gunther Hartmann | 5' triphosphate oligonucleotide with blunt end and uses thereof |
| US9249392B2 (en) | 2010-04-30 | 2016-02-02 | Cedars-Sinai Medical Center | Methods and compositions for maintaining genomic stability in cultured stem cells |
| US9845457B2 (en) | 2010-04-30 | 2017-12-19 | Cedars-Sinai Medical Center | Maintenance of genomic stability in cultured stem cells |
| EP2638158A4 (en) * | 2010-11-11 | 2015-07-15 | Univ Miami | COMPOSITIONS, CELLS, KITS AND METHODS FOR AUTOLOGOUS STEM CELL THERAPY |
| EP2508530A1 (en) | 2011-03-28 | 2012-10-10 | Rheinische Friedrich-Wilhelms-Universität Bonn | Purification of triphosphorylated oligonucleotides using capture tags |
| US9884076B2 (en) | 2012-06-05 | 2018-02-06 | Capricor, Inc. | Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy |
| CN107236735B (zh) | 2012-06-21 | 2019-11-08 | 米拉根医疗股份有限公司 | 包含锁核酸基序的基于寡核苷酸的抑制剂 |
| EP3563859B1 (en) | 2012-08-13 | 2021-10-13 | Cedars-Sinai Medical Center | Cardiosphere-derived exosomes for tissue regeneration |
| EP2712870A1 (en) | 2012-09-27 | 2014-04-02 | Rheinische Friedrich-Wilhelms-Universität Bonn | Novel RIG-I ligands and methods for producing them |
| ES2606636T3 (es) * | 2013-01-24 | 2017-03-24 | Pierre Fabre Médicament S.A.S. | Composición que comprende un antagomir encapsulado |
| DK2970968T3 (en) | 2013-03-15 | 2018-03-05 | Miragen Therapeutics Inc | CONNECTED BICYCLIC Nucleosides |
| US11253549B2 (en) | 2014-05-23 | 2022-02-22 | JangoBio, LLC | Methods to rebalance the hypothalamic-pituitary-gonadal axis |
| US11439668B2 (en) | 2014-05-23 | 2022-09-13 | JangoBio, LLC | Methods to differentiate stem cells into hormone-producing cells |
| EP4494699A3 (en) | 2014-10-03 | 2025-04-30 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
| US20160122762A1 (en) * | 2014-10-27 | 2016-05-05 | University Of Iowa Research Foundation | Methods of treating atherosclerosis |
| EP3247716A4 (en) | 2015-01-20 | 2018-10-17 | Miragen Therapeutics, Inc. | Mir-92 inhibitors and uses thereof |
| WO2017123662A1 (en) | 2016-01-11 | 2017-07-20 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction |
| WO2017210652A1 (en) | 2016-06-03 | 2017-12-07 | Cedars-Sinai Medical Center | Cdc-derived exosomes for treatment of ventricular tachyarrythmias |
| CN107586784B (zh) * | 2016-07-08 | 2020-08-25 | 田小利 | 一种分离的rnasek基因及其在制备抗血管衰老药物中的应用 |
| US11541078B2 (en) | 2016-09-20 | 2023-01-03 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders |
| JP7336769B2 (ja) | 2017-04-19 | 2023-09-01 | シーダーズ―シナイ メディカル センター | 骨格筋ジストロフィーを治療する方法及び組成物 |
| WO2019126068A1 (en) | 2017-12-20 | 2019-06-27 | Cedars-Sinai Medical Center | Engineered extracellular vesicles for enhanced tissue delivery |
| EP3749344A4 (en) | 2018-02-05 | 2022-01-26 | Cedars-Sinai Medical Center | METHODS OF THERAPEUTIC USE OF EXOSOMES AND Y-RNAS |
| EP3760209B1 (en) * | 2018-02-28 | 2023-11-22 | National University Corporation Tokyo Medical and Dental University | Ischemic-lesion-site-specific gene therapy |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7683036B2 (en) * | 2003-07-31 | 2010-03-23 | Regulus Therapeutics Inc. | Oligomeric compounds and compositions for use in modulation of small non-coding RNAs |
| EP2290073A3 (en) * | 2004-05-28 | 2011-08-31 | Asuragen, Inc. | Methods and compositions involving microRNA |
| WO2006133022A2 (en) * | 2005-06-03 | 2006-12-14 | The Johns Hopkins University | Compositions and methods for decreasing microrna expression for the treatment of neoplasia |
| EP2041317A4 (en) * | 2006-07-13 | 2009-10-14 | Univ Ohio State Res Found | METHODS AND COMPOSITIONS BASED ON MICRO-RNA FOR THE DIAGNOSIS AND TREATMENT OF COLON CANCER RELATED DISEASES |
| WO2008014008A2 (en) * | 2006-07-28 | 2008-01-31 | The Johns Hopkins University | Compositions and methods for modulating angiogenesis |
| WO2008070082A2 (en) * | 2006-12-04 | 2008-06-12 | The Johns Hopkins University | Stem-progenitor cell specific micro-ribonucleic acids and uses thereof |
| WO2009004632A2 (en) * | 2007-07-05 | 2009-01-08 | Yeda Research And Development Co. Ltd. | Methods of identifying components of a biological pathway and use of said components in regulating diseases associated with altered cell proliferation |
| CA2693031A1 (en) * | 2007-07-18 | 2009-01-22 | The Regents Of The University Colorado | Differential expression of micrornas in nonfailing versus failing human hearts |
| DE102007052114B4 (de) | 2007-10-30 | 2011-01-05 | T2Cure Gmbh | Verfahren zur Modulation der Funktion, des Wachstums oder der Differenzierung einer Zelle |
-
2007
- 2007-10-30 DE DE102007052114A patent/DE102007052114B4/de active Active
-
2008
- 2008-10-30 US US12/739,876 patent/US8258113B2/en active Active
- 2008-10-30 NO NO13179144A patent/NO2684955T3/no unknown
- 2008-10-30 HR HRP20170346TT patent/HRP20170346T1/hr unknown
- 2008-10-30 EP EP08844273.6A patent/EP2217704B1/de active Active
- 2008-10-30 EP EP13179144.4A patent/EP2684955B1/de active Active
- 2008-10-30 SI SI200831894T patent/SI2684955T1/en unknown
- 2008-10-30 ES ES08844273.6T patent/ES2618203T3/es active Active
- 2008-10-30 LT LTEP13179144.4T patent/LT2684955T/lt unknown
- 2008-10-30 JP JP2010531412A patent/JP5898843B2/ja not_active Expired - Fee Related
- 2008-10-30 DK DK08844273.6T patent/DK2217704T3/en active
- 2008-10-30 WO PCT/DE2008/001759 patent/WO2009056116A1/de not_active Ceased
- 2008-10-30 ES ES13179144.4T patent/ES2651287T3/es active Active
- 2008-10-30 PL PL08844273T patent/PL2217704T3/pl unknown
- 2008-10-30 PT PT131791444T patent/PT2684955T/pt unknown
- 2008-10-30 LT LTEP08844273.6T patent/LT2217704T/lt unknown
- 2008-10-30 SI SI200831774A patent/SI2217704T1/sl unknown
- 2008-10-30 CA CA2704290A patent/CA2704290C/en not_active Expired - Fee Related
- 2008-10-30 DK DK13179144.4T patent/DK2684955T3/en active
- 2008-10-30 HU HUE08844273A patent/HUE031559T2/hu unknown
- 2008-10-30 HU HUE13179144A patent/HUE037494T2/hu unknown
- 2008-10-30 PL PL13179144T patent/PL2684955T3/pl unknown
- 2008-10-30 PT PT88442736T patent/PT2217704T/pt unknown
- 2008-10-30 EP EP13179146.9A patent/EP2684956B1/de active Active
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2012
- 2012-08-08 US US13/569,786 patent/US8912158B2/en active Active
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2014
- 2014-06-05 JP JP2014116545A patent/JP2014196317A/ja active Pending
- 2014-07-31 US US14/448,119 patent/US9279123B2/en active Active
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2016
- 2016-02-10 US US15/040,487 patent/US9862949B2/en active Active
- 2016-06-24 JP JP2016125260A patent/JP2016199565A/ja active Pending
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2017
- 2017-02-22 CY CY20171100245T patent/CY1120360T1/el unknown
- 2017-12-04 HR HRP20171874TT patent/HRP20171874T1/hr unknown
- 2017-12-06 CY CY20171101283T patent/CY1120226T1/el unknown
- 2017-12-14 JP JP2017239230A patent/JP2018083817A/ja active Pending
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