SI1957630T2 - Izboljšana proizvodnja glikoproteinov z uporabo mangana - Google Patents

Izboljšana proizvodnja glikoproteinov z uporabo mangana

Info

Publication number
SI1957630T2
SI1957630T2 SI200632055T SI200632055T SI1957630T2 SI 1957630 T2 SI1957630 T2 SI 1957630T2 SI 200632055 T SI200632055 T SI 200632055T SI 200632055 T SI200632055 T SI 200632055T SI 1957630 T2 SI1957630 T2 SI 1957630T2
Authority
SI
Slovenia
Prior art keywords
glycoproteins
manganese
improved production
production
improved
Prior art date
Application number
SI200632055T
Other languages
English (en)
Other versions
SI1957630T1 (sl
Inventor
Christopher K. Crowell
Gustavo Grampp
Original Assignee
Amgen Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38051866&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1957630(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Amgen Inc. filed Critical Amgen Inc.
Publication of SI1957630T1 publication Critical patent/SI1957630T1/sl
Publication of SI1957630T2 publication Critical patent/SI1957630T2/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SI200632055T 2005-12-08 2006-12-06 Izboljšana proizvodnja glikoproteinov z uporabo mangana SI1957630T2 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74888005P 2005-12-08 2005-12-08
EP06847508.6A EP1957630B2 (en) 2005-12-08 2006-12-06 Improved production of glycoproteins using manganese
PCT/US2006/046609 WO2007070315A2 (en) 2005-12-08 2006-12-06 Improved production of glycoproteins using manganese

Publications (2)

Publication Number Publication Date
SI1957630T1 SI1957630T1 (sl) 2016-06-30
SI1957630T2 true SI1957630T2 (sl) 2023-07-31

Family

ID=38051866

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200632055T SI1957630T2 (sl) 2005-12-08 2006-12-06 Izboljšana proizvodnja glikoproteinov z uporabo mangana

Country Status (7)

Country Link
US (7) US7972810B2 (sl)
EP (4) EP4155385A1 (sl)
AU (1) AU2006324163B2 (sl)
CA (1) CA2630811C (sl)
ES (2) ES2913277T3 (sl)
SI (1) SI1957630T2 (sl)
WO (1) WO2007070315A2 (sl)

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PT2041270E (pt) * 2006-07-13 2013-12-27 Wyeth Llc Produção de glicoproteínas
AU2016244316B2 (en) * 2006-07-13 2018-07-12 Wyeth Llc Production of glycoproteins
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
MX2009002748A (es) 2006-09-13 2009-03-26 Abbott Lab Mejoras de cultivos celulares.
BRPI0920572A8 (pt) 2008-10-20 2015-10-27 Abbott Lab Inativação viral durante a purificação dos anticorpos
CN105111309A (zh) 2008-10-20 2015-12-02 Abbvie公司 使用a蛋白亲和层析分离和纯化抗体
EP2456871B1 (en) * 2009-07-24 2016-09-07 Dr. Reddy's Laboratories, Ltd. Production of erythropoiesis stimulating protein using metal ions
WO2011024024A1 (en) * 2009-08-28 2011-03-03 Avesthagen Limited A process for recovering darbepoeitin alfa isoforms
WO2011024025A1 (en) * 2009-08-28 2011-03-03 Avesthagen Limited An erythropoietin analogue and a method thereof
EP2325296A1 (en) 2009-11-20 2011-05-25 LEK Pharmaceuticals d.d. Production of glycoproteins with low N-glycolylneuraminic acid (Neu5Gc) content
WO2012149197A2 (en) * 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
WO2013114245A1 (en) 2012-01-30 2013-08-08 Dr. Reddy's Laboratories Limited Process of modulating man5 and/or afucosylation content of glycoprotein composition
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
WO2013158279A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Protein purification methods to reduce acidic species
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
CA2883272A1 (en) 2012-09-02 2014-03-06 Abbvie Inc. Methods to control protein heterogeneity
US9512214B2 (en) * 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
EP2830651A4 (en) 2013-03-12 2015-09-02 Abbvie Inc HUMAN ANTIBODIES THAT BIND TNF-ALPHA AND PREPARATION METHODS
US9217168B2 (en) 2013-03-14 2015-12-22 Momenta Pharmaceuticals, Inc. Methods of cell culture
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014159579A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
KR20150133833A (ko) * 2013-03-26 2015-11-30 코히러스 바이오사이언시즈, 인코포레이티드 단백질 생산 방법
WO2015011660A1 (en) 2013-07-23 2015-01-29 Biocon Limited Methods for controlling fucosylation levels in proteins
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
TR201610497T1 (tr) * 2014-01-29 2017-06-21 Lg Chemical Ltd Rekombi̇nant protei̇n galaktosi̇lasyonunu kültür ortaminin opti̇mi̇zasyonu vasitasiyla modüle etme yöntemi̇
BR112016017660B1 (pt) * 2014-02-27 2022-04-19 F. Hoffmann-La Roche Ag Método para a produção de uma glicoproteína recombinante
WO2015140700A1 (en) * 2014-03-19 2015-09-24 Dr. Reddy's Laboratories Limited Cell culture process
KR101660580B1 (ko) * 2014-04-02 2016-09-28 프레스티지 바이오파마 피티이. 엘티디. 항체의 당 함량 조절을 통한 항체의 제조 방법
WO2016004197A1 (en) * 2014-07-03 2016-01-07 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using cobalt
US20160130324A1 (en) 2014-10-31 2016-05-12 Shire Human Genetic Therapies, Inc. C1 Inhibitor Fusion Proteins and Uses Thereof
PL3227454T3 (pl) 2014-12-01 2020-07-27 Amgen Inc. Sposób manipulowania poziomem zawartości glikanów w glikoproteinie
KR102007930B1 (ko) 2014-12-31 2019-08-06 주식회사 엘지화학 재조합 당단백질의 글리코실화 조절 방법
US10844416B2 (en) * 2015-06-01 2020-11-24 Biogen Ma Inc. Manganese supplementation for control of glycosylation in mammalian cell culture process
JP7189767B2 (ja) 2015-11-19 2022-12-14 武田薬品工業株式会社 組換えヒトｃ１エステラーゼインヒビター及びその使用
US10519479B1 (en) * 2016-03-15 2019-12-31 Ares Trading S.A. Methods for modifying glycosylation using manganese

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Also Published As

Publication number Publication date
US8617878B2 (en) 2013-12-31
SI1957630T1 (sl) 2016-06-30
EP1957630B1 (en) 2016-02-17
EP2495308A1 (en) 2012-09-05
ES2913277T3 (es) 2022-06-01
US7972810B2 (en) 2011-07-05
EP1957630A2 (en) 2008-08-20
EP1957630B2 (en) 2023-03-29
CA2630811A1 (en) 2007-06-21
ES2564790T5 (es) 2023-08-25
US20070161084A1 (en) 2007-07-12
US9273110B2 (en) 2016-03-01
WO2007070315A2 (en) 2007-06-21
US20160222075A1 (en) 2016-08-04
US20220402986A1 (en) 2022-12-22
US20210047381A1 (en) 2021-02-18
EP3026109A1 (en) 2016-06-01
US20170355741A1 (en) 2017-12-14
EP3026109B1 (en) 2022-03-09
US20140088294A1 (en) 2014-03-27
ES2564790T3 (es) 2016-03-29
US20110287483A1 (en) 2011-11-24
AU2006324163A1 (en) 2007-06-21
WO2007070315A3 (en) 2007-12-27
AU2006324163B2 (en) 2013-05-02
EP4155385A1 (en) 2023-03-29
CA2630811C (en) 2016-05-31

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