SI1929297T1 - Bioloĺ ki oznaäśevalci pri multipli sklerozi in metode za njihovo uporabo - Google Patents

Bioloĺ ki oznaäśevalci pri multipli sklerozi in metode za njihovo uporabo

Info

Publication number
SI1929297T1
SI1929297T1 SI200631526T SI200631526T SI1929297T1 SI 1929297 T1 SI1929297 T1 SI 1929297T1 SI 200631526 T SI200631526 T SI 200631526T SI 200631526 T SI200631526 T SI 200631526T SI 1929297 T1 SI1929297 T1 SI 1929297T1
Authority
SI
Slovenia
Prior art keywords
biomarkers
methods
multiple sclerosis
sclerosis
Prior art date
Application number
SI200631526T
Other languages
English (en)
Inventor
Aaron B. Kantor
Susan Goelz
Jun Deng
Hua Lin
Christopher Becker
Original Assignee
Caprion Proteomics Usa, Llc
Biogen Idec Ma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Caprion Proteomics Usa, Llc, Biogen Idec Ma Inc. filed Critical Caprion Proteomics Usa, Llc
Publication of SI1929297T1 publication Critical patent/SI1929297T1/sl

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047Cells of the immune system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/285Demyelinating diseases; Multipel sclerosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Physiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SI200631526T 2005-09-29 2006-09-29 Bioloĺ ki oznaäśevalci pri multipli sklerozi in metode za njihovo uporabo SI1929297T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US72217205P 2005-09-29 2005-09-29
PCT/US2006/037924 WO2007041245A2 (en) 2005-09-29 2006-09-29 Biomarkers for multiple sclerosis and methods of use thereof
EP06815711A EP1929297B1 (en) 2005-09-29 2006-09-29 Biomarkers for multiple sclerosis and methods of use thereof

Publications (1)

Publication Number Publication Date
SI1929297T1 true SI1929297T1 (sl) 2013-06-28

Family

ID=37906719

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200631526T SI1929297T1 (sl) 2005-09-29 2006-09-29 Bioloĺ ki oznaäśevalci pri multipli sklerozi in metode za njihovo uporabo

Country Status (5)

Country Link
US (2) US20100062471A1 (sl)
EP (2) EP2517727A3 (sl)
DK (1) DK1929297T3 (sl)
SI (1) SI1929297T1 (sl)
WO (1) WO2007041245A2 (sl)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
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US9408891B2 (en) 2003-11-12 2016-08-09 The Trustees Of The University Of Pennsylvania Methods of using gelsolin to treat or prevent bacterial sepsis
DK1755661T3 (da) 2004-05-12 2014-06-16 Brigham & Womens Hospital Gelsolin til anvendelse til behandling af infektioner
ES2641879T3 (es) 2006-03-15 2017-11-14 The Brigham And Women's Hospital, Inc. Uso de gelsolina para diagnosticar y tratar enfermedades inflamatorias
EP2002258B1 (en) 2006-03-15 2017-09-27 The Brigham and Women's Hospital, Inc. Use of gelsolin to treat multiple sclerosis and to diagnose neurologic diseases
CA2662639C (en) * 2006-09-18 2013-06-04 Multiple Sclerosis Research Center Of New York Fetuin-a as a biomarker for multiple sclerosis
EP1988175A1 (en) * 2007-05-03 2008-11-05 Bayer Schering Pharma Aktiengesellschaft Predictive RNA profiles
DE102007041657A1 (de) * 2007-09-03 2009-03-05 Protagen Ag Markersequenzen für Multiple Sklerose und deren Verwendung
ES2531827T3 (es) 2008-01-25 2015-03-20 The General Hospital Corporation Usos terapéuticos de gelsolina en insuficiencia renal
EP2347352B1 (en) * 2008-09-16 2019-11-06 Beckman Coulter, Inc. Interactive tree plot for flow cytometry data
US10487148B2 (en) 2010-01-28 2019-11-26 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for treating aging-associated impairments
US20160208011A1 (en) 2010-01-28 2016-07-21 The Board Of Trustees Of The Leland Stanford Junior University Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
WO2017120461A1 (en) 2016-01-08 2017-07-13 The Board Of Trustees Of The Leland Stanford Junior University Ccr3 modulation in the treatment of aging-associated impairments, and compositions for practicing the same
US8709433B2 (en) * 2010-10-11 2014-04-29 Teva Pharmaceutical Industries Ltd. Cytokine biomarkers as predictive biomarkers of clinical response for Glatiramer acetate
ES2957957T3 (es) 2010-10-19 2024-01-30 Op T Llc Péptidos para modular la actividad de linfocitos T y usos de los mismos
US9161968B2 (en) 2011-04-08 2015-10-20 The Board Of Trustees Of The Leland Stanford Junior University Methods of neuroprotection involving macrophage colony stimulating factor receptor agonists
US8945935B2 (en) 2011-08-04 2015-02-03 Technion Research & Development Foundation Ltd. Diagnosing, prognosing and monitoring multiple sclerosis
US20160040236A1 (en) * 2013-03-15 2016-02-11 Biogen Ma Inc. Systems and methods for characterization of multiple sclerosis
CA2907224C (en) * 2013-03-15 2023-10-17 Sera Prognostics, Inc. Biomarkers and methods for predicting preeclampsia
ES2724327T3 (es) * 2013-07-25 2019-09-10 Theranos Ip Co Llc Sistemas y métodos para un laboratorio clínico distribuido
US10905779B2 (en) 2013-12-09 2021-02-02 The Board Of Trustees Of The Leland Stanford Junior University Methods for screening human blood products comprising plasma using immunocompromised rodent models
NZ720949A (en) 2013-12-09 2019-03-29 Univ Leland Stanford Junior Methods and compositions for treating aging-associated conditions
US20170108514A1 (en) * 2014-03-23 2017-04-20 The Regents Of The University Of Colorado, A Body Corporate Diagnosis of multiple sclerosis in human and animal subjects
WO2016040861A1 (en) * 2014-09-12 2016-03-17 Biogen Ma Inc. Systems and methods for characterization of multiple sclerosis
CN107921085B (zh) 2015-06-15 2021-10-22 小利兰·斯坦福大学托管委员会 用于治疗衰老相关病症的方法和组合物
IL256399B (en) 2015-06-19 2022-09-01 Sera Prognostics Inc Pairs of biomarkers for predicting premature birth
WO2017053838A1 (en) * 2015-09-23 2017-03-30 Oklahoma Medical Research Foundation Biomarkers for assessing subjects with multiple sclerosis
WO2017058999A2 (en) * 2015-09-29 2017-04-06 Crescendo Bioscience Biomarkers and methods for assessing response to inflammatory disease therapy withdrawal
CN109562280B (zh) * 2016-07-01 2022-11-22 尊严健康公司 复发-缓解型多发性硬化的诊断或预测因子
AU2018317902A1 (en) 2017-08-18 2020-03-05 Sera Prognostics, Inc. Pregnancy clock proteins for predicting due date and time to birth
US11793854B2 (en) 2019-03-21 2023-10-24 Op-T Llc Methods for reducing symptoms of multiple sclerosis using a six-amino acid long peptide that inhibits CD40-CD150 interaction
US20230266342A1 (en) * 2020-09-04 2023-08-24 Octave Bioscience, Inc. Biomarkers for Predicting Multiple Sclerosis Disease Progression

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6432662B1 (en) 1997-04-15 2002-08-13 Pierce Chemical Company Assay of peroxidase activity
WO2002033377A2 (en) * 2000-09-20 2002-04-25 Surromed, Inc. Biological markers for evaluating therapeutic treatment of inflammatory and autoimmune disorders
US6835927B2 (en) 2001-10-15 2004-12-28 Surromed, Inc. Mass spectrometric quantification of chemical mixture components
CA2494422A1 (en) * 2002-08-02 2004-02-19 Glycominds Ltd. Method for diagnosing multiple sclerosis

Also Published As

Publication number Publication date
EP1929297A2 (en) 2008-06-11
EP2517727A3 (en) 2013-10-30
US20100062471A1 (en) 2010-03-11
EP2517727A2 (en) 2012-10-31
WO2007041245A2 (en) 2007-04-12
US20150031562A1 (en) 2015-01-29
EP1929297A4 (en) 2010-02-24
DK1929297T3 (da) 2013-03-04
WO2007041245A3 (en) 2009-05-07
EP1929297B1 (en) 2012-11-21

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