SI1899377T1 - Humanizirana protitelesa, specifična za NOGO-A, in njihove farmacevtske uporabe - Google Patents

Humanizirana protitelesa, specifična za NOGO-A, in njihove farmacevtske uporabe

Info

Publication number
SI1899377T1
SI1899377T1 SI200631454T SI200631454T SI1899377T1 SI 1899377 T1 SI1899377 T1 SI 1899377T1 SI 200631454 T SI200631454 T SI 200631454T SI 200631454 T SI200631454 T SI 200631454T SI 1899377 T1 SI1899377 T1 SI 1899377T1
Authority
SI
Slovenia
Prior art keywords
phrarmaceutical
nogo
antibodies specific
humanised antibodies
humanised
Prior art date
Application number
SI200631454T
Other languages
English (en)
Slovenian (sl)
Inventor
Jonathan Henry GlaxoSmithKline ELLIS
Paul Andrew GlaxoSmithKline HAMBLIN
Farhana GlaxoSmithKline HUSSAIN
Alan Peter GlaxoSmithKline LEWIS
Ruth GlaxoSmithKline MCADAM
Rabinder GlaxoSmithKline PRINJHA
Paul GlaxoSmithKline WILSON
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0513766A external-priority patent/GB0513766D0/en
Priority claimed from GB0525448A external-priority patent/GB0525448D0/en
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of SI1899377T1 publication Critical patent/SI1899377T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI200631454T 2005-07-05 2006-07-03 Humanizirana protitelesa, specifična za NOGO-A, in njihove farmacevtske uporabe SI1899377T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0513766A GB0513766D0 (en) 2005-07-05 2005-07-05 Immunoglobulins
GB0525448A GB0525448D0 (en) 2005-12-14 2005-12-14 Immunoglobulins
EP06776123A EP1899377B1 (en) 2005-07-05 2006-07-03 Humanised antibodies specific for nogo-a and phrarmaceutical uses thereof
PCT/EP2006/006535 WO2007003421A2 (en) 2005-07-05 2006-07-03 Humanised antibodies specific for nogo-a and pharmaceutical uses thereof

Publications (1)

Publication Number Publication Date
SI1899377T1 true SI1899377T1 (sl) 2012-12-31

Family

ID=37604821

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200631454T SI1899377T1 (sl) 2005-07-05 2006-07-03 Humanizirana protitelesa, specifična za NOGO-A, in njihove farmacevtske uporabe

Country Status (22)

Country Link
EP (1) EP1899377B1 (es)
JP (1) JP2009500363A (es)
KR (1) KR20080030960A (es)
AU (1) AU2006265276B2 (es)
BR (1) BRPI0612734A2 (es)
CA (1) CA2614076A1 (es)
CR (1) CR9623A (es)
CY (1) CY1113310T1 (es)
DK (1) DK1899377T3 (es)
EA (1) EA014291B1 (es)
ES (1) ES2391902T3 (es)
HK (1) HK1115598A1 (es)
HR (1) HRP20120851T1 (es)
IL (1) IL188282A (es)
MA (1) MA29625B1 (es)
NO (1) NO20076663L (es)
NZ (1) NZ564567A (es)
PL (1) PL1899377T3 (es)
PT (1) PT1899377E (es)
SG (1) SG162829A1 (es)
SI (1) SI1899377T1 (es)
WO (1) WO2007003421A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1874821T3 (da) 2005-04-26 2013-07-08 Trion Pharma Gmbh Kombination af antistoffer med glykokortikoider til behandling af kræft
MX2009013328A (es) 2007-06-25 2010-06-02 Esbatech An Alcon Biomedical R Metodos para modificar anticuerpos, y anticuerpos modificados con propiedades funcionales mejoradas.
DK2207808T3 (da) 2007-11-02 2013-08-05 Novartis Ag Forbedrede Nogo-A-bindingsmolekyler samt deres farmaceutiske anvendelse
CA2730473A1 (en) * 2008-07-11 2010-01-14 Glaxo Group Limited Novel treatment
GB201709970D0 (en) 2017-06-22 2017-08-09 Kymab Ltd Bispecific antigen-binding molecules
SI3723858T1 (sl) 2018-12-21 2022-04-29 Kymab Limited Bispecifično protitelo FIXAXFX s skupno lahko verigo
GB2590642B (en) * 2019-12-20 2024-02-14 Kymab Ltd Improved lambda antibodies

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0228832D0 (en) * 2002-12-10 2003-01-15 Novartis Ag Organic compound
GB0321997D0 (en) * 2003-09-19 2003-10-22 Novartis Ag Organic compound
TWI329649B (en) * 2003-12-22 2010-09-01 Glaxo Group Ltd Immunoglobulins

Also Published As

Publication number Publication date
JP2009500363A (ja) 2009-01-08
NZ564567A (en) 2010-09-30
DK1899377T3 (da) 2012-11-12
IL188282A0 (en) 2008-04-13
CR9623A (es) 2008-04-10
CA2614076A1 (en) 2007-01-11
SG162829A1 (en) 2010-07-29
IL188282A (en) 2011-04-28
AU2006265276A1 (en) 2007-01-11
WO2007003421A3 (en) 2007-04-12
AU2006265276B2 (en) 2011-10-13
PT1899377E (pt) 2012-11-20
EP1899377B1 (en) 2012-08-22
NO20076663L (no) 2008-02-27
BRPI0612734A2 (pt) 2010-11-30
PL1899377T3 (pl) 2013-01-31
EP1899377A2 (en) 2008-03-19
EA200702634A1 (ru) 2008-06-30
KR20080030960A (ko) 2008-04-07
MA29625B1 (fr) 2008-07-01
HK1115598A1 (en) 2008-12-05
WO2007003421A2 (en) 2007-01-11
CY1113310T1 (el) 2016-04-13
ES2391902T3 (es) 2012-11-30
HRP20120851T1 (hr) 2012-11-30
EA014291B1 (ru) 2010-10-29

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