SI1711177T1 - Derivati 1H-tieno 2,3-c pirazola, uporabni kot inhibitorji kinaze I - Google Patents
Derivati 1H-tieno 2,3-c pirazola, uporabni kot inhibitorji kinaze IInfo
- Publication number
- SI1711177T1 SI1711177T1 SI200530297T SI200530297T SI1711177T1 SI 1711177 T1 SI1711177 T1 SI 1711177T1 SI 200530297 T SI200530297 T SI 200530297T SI 200530297 T SI200530297 T SI 200530297T SI 1711177 T1 SI1711177 T1 SI 1711177T1
- Authority
- SI
- Slovenia
- Prior art keywords
- thieno
- kinase
- inhibitors
- pyrazole derivatives
- derivatives useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Psychiatry (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Virology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54145204P | 2004-02-03 | 2004-02-03 | |
| PCT/EP2005/001021 WO2005074922A1 (en) | 2004-02-03 | 2005-02-02 | 1H-THIENO[2,3-c]PYRAZOLE DERIVATIVES USEFUL AS KINASE INHIBITORS |
| EP05701307A EP1711177B1 (en) | 2004-02-03 | 2005-02-02 | 1H-THIENO 2,3-c PYRAZOLE DERIVATIVES USEFUL AS KINASE I INHIBITORS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1711177T1 true SI1711177T1 (sl) | 2008-10-31 |
Family
ID=34837492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200530297T SI1711177T1 (sl) | 2004-02-03 | 2005-02-02 | Derivati 1H-tieno 2,3-c pirazola, uporabni kot inhibitorji kinaze I |
Country Status (38)
| Country | Link |
|---|---|
| US (2) | US8138217B2 (sl) |
| EP (1) | EP1711177B1 (sl) |
| JP (1) | JP4908233B2 (sl) |
| KR (1) | KR20060124734A (sl) |
| CN (1) | CN1946395B (sl) |
| AP (1) | AP2006003701A0 (sl) |
| AR (1) | AR047531A1 (sl) |
| AT (1) | ATE396724T1 (sl) |
| AU (1) | AU2005210114B2 (sl) |
| BR (1) | BRPI0507375A (sl) |
| CA (1) | CA2555262C (sl) |
| CR (1) | CR8546A (sl) |
| CY (1) | CY1108246T1 (sl) |
| DE (1) | DE602005007181D1 (sl) |
| DK (1) | DK1711177T3 (sl) |
| DO (1) | DOP2005000014A (sl) |
| EA (1) | EA011032B1 (sl) |
| EC (1) | ECSP066767A (sl) |
| ES (1) | ES2307144T3 (sl) |
| GE (1) | GEP20094633B (sl) |
| GT (1) | GT200500020A (sl) |
| HK (1) | HK1101343A1 (sl) |
| IL (1) | IL177141A0 (sl) |
| MA (1) | MA28429B1 (sl) |
| MX (1) | MXPA06008787A (sl) |
| NO (1) | NO20063768L (sl) |
| NZ (1) | NZ548896A (sl) |
| PA (1) | PA8622801A1 (sl) |
| PE (1) | PE20051095A1 (sl) |
| PL (1) | PL1711177T3 (sl) |
| PT (1) | PT1711177E (sl) |
| SI (1) | SI1711177T1 (sl) |
| TN (1) | TNSN06244A1 (sl) |
| TW (1) | TW200526204A (sl) |
| UA (1) | UA86223C2 (sl) |
| UY (1) | UY28738A1 (sl) |
| WO (1) | WO2005074922A1 (sl) |
| ZA (1) | ZA200606179B (sl) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4533138B2 (ja) * | 2002-07-25 | 2010-09-01 | ファイザー イタリア ソシエタ ア レスポンサビリタ リミタータ | キナーゼ阻害剤としての縮環ヘテロ環式ピラゾール誘導体 |
| WO2007009898A1 (en) * | 2005-07-19 | 2007-01-25 | Nerviano Medical Sciences S.R.L. | 1h-thieno[2,3-c]pyrazole compounds useful as kinase inhibitors |
| AU2006298563A1 (en) * | 2005-10-06 | 2007-04-12 | Merck & Co., Inc. | Use of fused pyrrole carboxylic acids for the treatment of neurodegenerative and psychiatric diseases as D-amino acid oxidase inhibitors |
| US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| ATE524177T1 (de) | 2006-03-30 | 2011-09-15 | Nerviano Medical Sciences Srl | Verwendung eines kinasehemmers zur behandlung von bestimmten resistenten tumoren |
| EP2051981B1 (en) * | 2006-05-31 | 2010-08-25 | Nerviano Medical Sciences S.R.L. | 1h-furo[3,2-c] pyrazole compounds useful as kinase inhibitors |
| FR2904626B1 (fr) * | 2006-08-03 | 2008-09-19 | Sanofi Aventis | Derives de pyrazolo[4,3]thiazole, leur preparation et leur application en therapeutique |
| JP2010505962A (ja) | 2006-10-09 | 2010-02-25 | 武田薬品工業株式会社 | キナーゼ阻害剤 |
| KR100923540B1 (ko) | 2007-11-23 | 2009-10-27 | 한국과학기술연구원 | 5-아실하이드라진카르보닐-3,4-디치환 피라졸 유도체 및이의 제조방법 |
| CL2009001158A1 (es) * | 2008-05-15 | 2009-10-23 | Nerviano Medical Sciences Srl | Compuestos derivados de los acidos carboxilicos, tales como 5,6-dihiro-4h-pirrolo[3,4-c]pirazol, furo[3,2-c]pirazol, tieno[2,3-c]pirazol, 4,5,6,7-tetrahidropirazol[4,3-c]piridina e indazol; composicion farmaceutica; y su uso en el tratamiento de trastornos proliferativos celulares asociados a la actividad de proteina quinasa alterada, tal como el cancer. |
| AU2010229144B2 (en) * | 2009-03-23 | 2012-07-12 | Merck Sharp & Dohme Corp. | P2X3, receptor antagonists for treatment of pain |
| US9255072B2 (en) | 2011-03-04 | 2016-02-09 | National Health Rsearch Institutes | Pyrazole compounds and thiazole compounds as protein kinases inhibitors |
| JP6314128B2 (ja) * | 2012-04-05 | 2018-04-18 | ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ | 新たなアルキル化剤 |
| EP3663299B1 (en) * | 2017-08-01 | 2023-03-08 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Bicyclic compound acting as ror gamma inhibitor |
| EP3717492B1 (en) * | 2017-11-30 | 2023-05-24 | Hanmi Pharm. Co., Ltd. | Thieno[3,2-d]pyrimidine compound having inhibitory activity for protein kinase |
| CN113072562B (zh) * | 2021-04-06 | 2022-01-14 | 山东大学 | 一种GSK-3β抑制剂及其制备方法与应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2015566B3 (es) | 1986-02-19 | 1990-09-01 | Duphar Int Res B V | Nuevos compuestos tio que tienen actividad fungicida. |
| GB9911053D0 (en) | 1999-05-12 | 1999-07-14 | Pharmacia & Upjohn Spa | 4,5,6,7-tetrahydroindazole derivatives process for their preparation and their use as antitumour agents |
| DE60023012T2 (de) | 1999-08-12 | 2006-07-20 | Pharmacia Italia S.P.A. | 3(5)-amino-pyrazolderivate, deren herstellungsverfahren und verwendung als krebshemmende mittel |
| US6387900B1 (en) | 1999-08-12 | 2002-05-14 | Pharmacia & Upjohn S.P.A. | 3(5)-ureido-pyrazole derivatives process for their preparation and their use as antitumor agents |
| MXPA03001169A (es) * | 2000-08-10 | 2003-06-30 | Pharmacia Italia Spa | Biciclo-pirazoles activos como inhibidores de quinasa, proceso para su preparacion y composiciones farmaceuticas que comprenden los mismos. |
| EP1345909A1 (en) | 2000-11-27 | 2003-09-24 | Pharmacia Italia S.p.A. | Phenylacetamido-pyrazole derivatives and their use as antitumor agents |
| EP1379524A2 (en) | 2001-01-26 | 2004-01-14 | Pharmacia Italia S.p.A. | Chromane derivatives, process for their preparation and their use as antitumor agents |
| IL160744A0 (en) | 2001-09-26 | 2004-08-31 | Pharmacia Italia Spa | Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them |
| CA2486101C (en) * | 2002-05-17 | 2009-07-07 | Pharmacia Italia S.P.A. | Aminoindazole derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions comprising them |
| ES2304531T3 (es) * | 2002-07-17 | 2008-10-16 | Pfizer Italia S.R.L. | Derivados heterobiciclicos de pirazol como inhibidores de quinasa. |
| JP4533138B2 (ja) * | 2002-07-25 | 2010-09-01 | ファイザー イタリア ソシエタ ア レスポンサビリタ リミタータ | キナーゼ阻害剤としての縮環ヘテロ環式ピラゾール誘導体 |
| US20050026984A1 (en) * | 2003-07-29 | 2005-02-03 | Aventis Pharma S.A. | Substituted thieno [2,3-c] pyrazoles and their use as medicinal products |
-
2005
- 2005-01-28 TW TW094102761A patent/TW200526204A/zh unknown
- 2005-02-02 AU AU2005210114A patent/AU2005210114B2/en not_active Ceased
- 2005-02-02 KR KR1020067017754A patent/KR20060124734A/ko not_active Application Discontinuation
- 2005-02-02 CN CN200580005922.0A patent/CN1946395B/zh not_active Expired - Fee Related
- 2005-02-02 WO PCT/EP2005/001021 patent/WO2005074922A1/en active IP Right Grant
- 2005-02-02 EA EA200601418A patent/EA011032B1/ru not_active IP Right Cessation
- 2005-02-02 SI SI200530297T patent/SI1711177T1/sl unknown
- 2005-02-02 JP JP2006551790A patent/JP4908233B2/ja not_active Expired - Fee Related
- 2005-02-02 AP AP2006003701A patent/AP2006003701A0/xx unknown
- 2005-02-02 DO DO2005000014A patent/DOP2005000014A/es unknown
- 2005-02-02 EP EP05701307A patent/EP1711177B1/en active Active
- 2005-02-02 PT PT05701307T patent/PT1711177E/pt unknown
- 2005-02-02 AR ARP050100399A patent/AR047531A1/es not_active Application Discontinuation
- 2005-02-02 AT AT05701307T patent/ATE396724T1/de active
- 2005-02-02 UA UAA200609515A patent/UA86223C2/uk unknown
- 2005-02-02 BR BRPI0507375-8A patent/BRPI0507375A/pt not_active IP Right Cessation
- 2005-02-02 DE DE602005007181T patent/DE602005007181D1/de active Active
- 2005-02-02 DK DK05701307T patent/DK1711177T3/da active
- 2005-02-02 MX MXPA06008787A patent/MXPA06008787A/es active IP Right Grant
- 2005-02-02 PE PE2005000121A patent/PE20051095A1/es not_active Application Discontinuation
- 2005-02-02 GE GEAP20059600A patent/GEP20094633B/en unknown
- 2005-02-02 ES ES05701307T patent/ES2307144T3/es active Active
- 2005-02-02 NZ NZ548896A patent/NZ548896A/en unknown
- 2005-02-02 PL PL05701307T patent/PL1711177T3/pl unknown
- 2005-02-02 CA CA2555262A patent/CA2555262C/en not_active Expired - Fee Related
- 2005-02-03 GT GT200500020A patent/GT200500020A/es unknown
- 2005-02-03 PA PA20058622801A patent/PA8622801A1/es unknown
- 2005-02-03 US US11/050,360 patent/US8138217B2/en not_active Expired - Fee Related
- 2005-02-03 UY UY28738A patent/UY28738A1/es not_active Application Discontinuation
-
2006
- 2006-07-26 ZA ZA200606179A patent/ZA200606179B/xx unknown
- 2006-07-27 IL IL177141A patent/IL177141A0/en unknown
- 2006-08-03 CR CR8546A patent/CR8546A/es not_active Application Discontinuation
- 2006-08-03 MA MA29227A patent/MA28429B1/fr unknown
- 2006-08-03 TN TNP2006000244A patent/TNSN06244A1/fr unknown
- 2006-08-10 EC EC2006006767A patent/ECSP066767A/es unknown
- 2006-08-23 NO NO20063768A patent/NO20063768L/no not_active Application Discontinuation
-
2007
- 2007-06-07 HK HK07106106.1A patent/HK1101343A1/xx not_active IP Right Cessation
-
2008
- 2008-08-07 CY CY20081100834T patent/CY1108246T1/el unknown
-
2012
- 2012-02-24 US US13/404,697 patent/US8481584B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT1711177E (pt) | Derivados de 1h-tieno[2,3-c]pirazole úteis como inibidores de quinase i | |
| HRP20180578T1 (hr) | Pirolo[2,3-b]piridin-4-il-amini i pirolo[2m3-b]pirimidin-4-il-amini kao inhibitori janus kinaze | |
| AP2048A (en) | Diazepinoindole derivatives as kinase inhibitors | |
| IL172132A0 (en) | Thienopyridone derivatives as kinase inhibitors | |
| IS8192A (is) | Pýrróló[3,4-c] pýrasól afleiður virkar sem kínasahindrar | |
| TWI349672B (en) | Pyrazolo-quinazoline derivatives, process for their preparation and their use as kinase inhibitors | |
| IL165515A0 (en) | Bisindolyl-maleimid derivatives as kinase inhibitors | |
| IL173200A0 (en) | Piperidyl-quinazoline derivatives as tyrosine kinase inhibitors | |
| ZA201202026B (en) | PYROLO[2,3-b] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | |
| IL173381A0 (en) | 2-aminophenyl-4-phenylpyrimidines as kinase inhibitors | |
| IL173139A0 (en) | Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors | |
| AU2003254337A1 (en) | Heterobicyclic pyrazole derivatives as kinase inhibitors | |
| ZA200703835B (en) | Heterocyclic substituted bisarylurea derivatives as kinase inhibitors | |
| AU2003250040A1 (en) | Condensed heterocyclic pyrazole derivatives as kinase inhibitors | |
| ZA200709919B (en) | Pyrrol (2,3-B) pyridine derivatives protein kinase inhibitors | |
| IL178688A0 (en) | THIENO [3,2-b] PYRIDINE-6-CARBONITRILES AS PROTEIN KINASE INHIBITORS | |
| AU2002339506A1 (en) | Heterocycle-carboxamide derivatives as raf kinase inhibitors | |
| AU2002307861A1 (en) | Imidazole-2-carboxamide derivatives as raf kinase inhibitors |