SI1453852T1 - Selektivni arilgvanidinpeptidi kot inhibitorji urokinaze - Google Patents

Selektivni arilgvanidinpeptidi kot inhibitorji urokinaze

Info

Publication number
SI1453852T1
SI1453852T1 SI200230493T SI200230493T SI1453852T1 SI 1453852 T1 SI1453852 T1 SI 1453852T1 SI 200230493 T SI200230493 T SI 200230493T SI 200230493 T SI200230493 T SI 200230493T SI 1453852 T1 SI1453852 T1 SI 1453852T1
Authority
SI
Slovenia
Prior art keywords
urokinase inhibitors
selective urokinase
selective
inhibitors
urokinase
Prior art date
Application number
SI200230493T
Other languages
English (en)
Inventor
Stefan Sperl
Original Assignee
Wilex Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2002140452 external-priority patent/DE10240452A1/de
Application filed by Wilex Ag filed Critical Wilex Ag
Publication of SI1453852T1 publication Critical patent/SI1453852T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • C07K5/06069—Ser-amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
SI200230493T 2001-12-12 2002-12-12 Selektivni arilgvanidinpeptidi kot inhibitorji urokinaze SI1453852T1 (sl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10161062 2001-12-12
DE2002140452 DE10240452A1 (de) 2002-09-02 2002-09-02 Urokinase Inhibitoren
EP02787942A EP1453852B1 (de) 2001-12-12 2002-12-12 Selektive arylguanidinpeptide als urokinaseinhibitoren
PCT/EP2002/014157 WO2003053999A2 (de) 2001-12-12 2002-12-12 Selektive arylguanidinpeptide als urokinaseinhibitoren

Publications (1)

Publication Number Publication Date
SI1453852T1 true SI1453852T1 (sl) 2007-06-30

Family

ID=26010763

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200230493T SI1453852T1 (sl) 2001-12-12 2002-12-12 Selektivni arilgvanidinpeptidi kot inhibitorji urokinaze

Country Status (11)

Country Link
US (1) US20040266766A1 (sl)
EP (1) EP1453852B1 (sl)
JP (1) JP4418680B2 (sl)
AU (1) AU2002352245B2 (sl)
CA (1) CA2470078C (sl)
DE (1) DE50209313D1 (sl)
DK (1) DK1453852T3 (sl)
ES (1) ES2275937T3 (sl)
PT (1) PT1453852E (sl)
SI (1) SI1453852T1 (sl)
WO (1) WO2003053999A2 (sl)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003219039A1 (en) * 2002-03-11 2003-09-22 Curacyte Ag Urokinase inhibitors, production and use thereof
DE10301300B4 (de) * 2003-01-15 2009-07-16 Curacyte Chemistry Gmbh Verwendung von acylierten 4-Amidino- und 4-Guanidinobenzylaminen zur Inhibierung von Plasmakallikrein
DE10342108A1 (de) * 2003-09-11 2005-04-14 Curacyte Chemistry Gmbh Basisch-substituierte Benzylaminanaloga als Inhibitoren des Gerinnungsfaktors Xa, ihre Herstellung und Verwendung
DE102004045720A1 (de) * 2004-09-21 2006-03-23 Wilex Ag Stabile Dosierungsform von Phenylalanin-Derivaten
RU2410087C2 (ru) 2005-06-24 2011-01-27 Вилекс Аг Применение ингибиторов урокиназы для лечения и/или предупреждения невропатологических заболеваний
DE102006050672A1 (de) 2006-10-24 2008-04-30 Curacyte Discovery Gmbh Hemmstoffe des Plasmins und des Plasmakallikreins
KR102051687B1 (ko) * 2011-10-26 2019-12-17 알러간, 인코포레이티드 포르밀 펩티드 수용체 유사-1 (fprl-1) 수용체 조절자로서의 n-유레아 치환된 아미노산의 아미드 유도체
WO2023203473A1 (en) * 2022-04-19 2023-10-26 Iridea S.R.L. Arylthio derivatives with pharmacological activity

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5726159A (en) * 1994-03-04 1998-03-10 Eli Lilly And Company Antithrombotic agents
US6576613B1 (en) * 1998-07-24 2003-06-10 Corvas International, Inc. Title inhibitors of urokinase
DE19940389A1 (de) * 1999-08-25 2001-03-01 Wilex Biotechnology Gmbh Selektive Inhibitoren des Urokinase-Plasminogen Aktivators
DE10013715A1 (de) * 2000-03-20 2001-09-27 Wilex Biotechnology Gmbh Hochselektive Inhibitoren des Urokinase-Plasminogenaktivators
DE10029015A1 (de) * 2000-06-15 2001-12-20 Curacyte Ag Hemmstoffe für den Gerinnungsfaktor Xa
DE10029014A1 (de) * 2000-06-15 2001-12-20 Univ Schiller Jena Urokinase-Hemmstoffe
NZ547626A (en) * 2000-08-11 2007-10-26 Wilex Ag Non-covalent inhibitors of urokinase and blood vessel formation

Also Published As

Publication number Publication date
DE50209313D1 (de) 2007-03-08
JP2005518388A (ja) 2005-06-23
US20040266766A1 (en) 2004-12-30
WO2003053999A3 (de) 2003-11-06
WO2003053999A2 (de) 2003-07-03
CA2470078C (en) 2011-07-12
AU2002352245B2 (en) 2008-10-16
CA2470078A1 (en) 2003-07-03
JP4418680B2 (ja) 2010-02-17
DK1453852T3 (da) 2007-05-21
ES2275937T3 (es) 2007-06-16
EP1453852A2 (de) 2004-09-08
AU2002352245A1 (en) 2003-07-09
EP1453852B1 (de) 2007-01-17
PT1453852E (pt) 2007-02-28

Similar Documents

Publication Publication Date Title
GB0125445D0 (en) Protease Inhibitors
IL157656A0 (en) Metalloproteinase inhibitors
IL157570A0 (en) Metalloproteinase inhibitors
IL150964A0 (en) Protease inhibitors
IL157658A0 (en) Metalloproteinase inhibitors
AU2002361861A8 (en) Selective 11beta-hsd inhibitors and methods for use thereof
AU2001285750A1 (en) Urokinase inhibitors
IL153421A0 (en) Protease inhibitors
SI1453852T1 (sl) Selektivni arilgvanidinpeptidi kot inhibitorji urokinaze
IL151087A0 (en) Protease inhibitors
EP1401453A4 (en) PROTEASE INHIBITORS
AU2001283336A1 (en) Selective urokinase inhibitors
HUP0301964A2 (en) Protease inhibitors
GB0109278D0 (en) Enzyme inhibitors
AU2002237142A1 (en) Urokinase inhibitors
GB0128453D0 (en) Inhibitors
GB0101135D0 (en) Inhibitors
GB0101134D0 (en) Inhibitors
GB0109145D0 (en) Enzyme inhibitors
GB0101537D0 (en) Enzyme inhibitors
GB0102018D0 (en) Enzyme inhibitors
GB0102194D0 (en) Enzyme inhibitors
GB0106564D0 (en) Enzyme inhibitors
GB0029730D0 (en) Inhibitors
GB0015996D0 (en) Inhibitors