SI1051393T1 - New derivatives of sulfonic, phosphonic and phosphinic aminoalkane acids, their production and their use as medicaments - Google Patents

New derivatives of sulfonic, phosphonic and phosphinic aminoalkane acids, their production and their use as medicaments

Info

Publication number
SI1051393T1
SI1051393T1 SI9830537T SI9830537T SI1051393T1 SI 1051393 T1 SI1051393 T1 SI 1051393T1 SI 9830537 T SI9830537 T SI 9830537T SI 9830537 T SI9830537 T SI 9830537T SI 1051393 T1 SI1051393 T1 SI 1051393T1
Authority
SI
Slovenia
Prior art keywords
radical
aminoalkane
acids
phosphinic
phosphonic
Prior art date
Application number
SI9830537T
Other languages
English (en)
Slovenian (sl)
Inventor
Jean-Jacques Berthelon
Philippe Durbin
Original Assignee
Merck Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Sante filed Critical Merck Sante
Publication of SI1051393T1 publication Critical patent/SI1051393T1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/30Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301Acyclic saturated acids which can have further substituents on alkyl
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/13Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton
    • C07C309/14Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton
    • C07C309/15Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing nitrogen atoms, not being part of nitro or nitroso groups, bound to the carbon skeleton containing amino groups bound to the carbon skeleton the nitrogen atom of at least one of the amino groups being part of any of the groups, X being a hetero atom, Y being any atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01Sulfonic acids
    • C07C309/02Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/24Sulfonic acids having sulfo groups bound to acyclic carbon atoms of a carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808Acyclic saturated acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Addiction (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SI9830537T 1998-01-27 1998-01-27 New derivatives of sulfonic, phosphonic and phosphinic aminoalkane acids, their production and their use as medicaments SI1051393T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98904231A EP1051393B1 (fr) 1998-01-27 1998-01-27 Nouveaux derives d'acides aminoalkane sulfoniques, phosphoniques et phosphiniques, leur preparation et leur utilisation comme medicaments
PCT/FR1998/000147 WO1999037606A1 (fr) 1998-01-27 1998-01-27 Nouveaux derives d'acides aminoalkane sulfoniques, phosphoniques et phosphiniques, leur preparation et leur utilisation comme medicaments

Publications (1)

Publication Number Publication Date
SI1051393T1 true SI1051393T1 (en) 2004-02-29

Family

ID=9521619

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830537T SI1051393T1 (en) 1998-01-27 1998-01-27 New derivatives of sulfonic, phosphonic and phosphinic aminoalkane acids, their production and their use as medicaments

Country Status (12)

Country Link
US (1) US6265437B1 (enExample)
EP (1) EP1051393B1 (enExample)
JP (1) JP4156795B2 (enExample)
AT (1) ATE251129T1 (enExample)
AU (1) AU762988B2 (enExample)
CA (1) CA2319272C (enExample)
DE (1) DE69818709T2 (enExample)
DK (1) DK1051393T3 (enExample)
ES (1) ES2209110T3 (enExample)
PT (1) PT1051393E (enExample)
SI (1) SI1051393T1 (enExample)
WO (1) WO1999037606A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070010573A1 (en) * 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
AR049199A1 (es) * 2004-06-04 2006-07-05 Aventis Pharma Inc Derivados de acido propano-fosfinico sustituido
JP5145537B2 (ja) 2004-12-22 2013-02-20 ビーエイチアイ リミテッド パートナーシップ アミロイド関連疾患を治療するための方法および組成物
FR2899895B1 (fr) * 2006-04-12 2010-09-17 Servier Lab Nouveaux sels de strontium d'acides sulfoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP5607930B2 (ja) * 2006-10-12 2014-10-15 ビーエイチアイ リミテッド パートナーシップ 3−アミノ−1−プロパンスルホン酸を送達するための方法、化合物、組成物および媒体
KR100877134B1 (ko) * 2007-05-03 2009-01-09 주식회사 엔지켐 아캄프로세이트 칼슘의 제조방법
WO2009033079A1 (en) * 2007-09-07 2009-03-12 Xenoport, Inc. Externally masked neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use
TW200924747A (en) * 2007-09-07 2009-06-16 Xenoport Inc Simple pantoic acid ester neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use
TW200932734A (en) * 2007-10-15 2009-08-01 Xenoport Inc Internally masked neopentyl sulfonyl ester cyclization release prodrugs of acamprosate, compositions thereof, and methods of use
DE102008048791A1 (de) * 2008-09-24 2010-03-25 Merck Patent Gmbh Neue Kristallform von Calcium-3-Acetylaminopropan-1-sulfonat
IT1392327B1 (it) * 2008-09-26 2012-02-28 Laboratorio Chimico Int Spa Nuova forma polimorfa del calcio acamprosato

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2384751A1 (fr) * 1977-03-23 1978-10-20 Francaise Coop Pharma Nouveaux derives de la taurine a activite neuro-musculaire renforcee
FR2457281A1 (fr) * 1979-05-23 1980-12-19 Meram Lab Nouveaux derives de l'acide 3-aminopropanesulfonique ayant une activite membranaire renforcee

Also Published As

Publication number Publication date
AU6219098A (en) 1999-08-09
AU762988B2 (en) 2003-07-10
EP1051393B1 (fr) 2003-10-01
EP1051393A1 (fr) 2000-11-15
JP4156795B2 (ja) 2008-09-24
ATE251129T1 (de) 2003-10-15
US6265437B1 (en) 2001-07-24
CA2319272C (en) 2005-11-08
DK1051393T3 (da) 2004-02-02
ES2209110T3 (es) 2004-06-16
PT1051393E (pt) 2004-02-27
DE69818709T2 (de) 2004-08-19
DE69818709D1 (en) 2003-11-06
JP2002501040A (ja) 2002-01-15
WO1999037606A1 (fr) 1999-07-29
CA2319272A1 (en) 1999-07-29

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