SG44991G - 13-substituted derivatives of avermectin aglycones - Google Patents

13-substituted derivatives of avermectin aglycones

Info

Publication number
SG44991G
SG44991G SG44991A SG44991A SG44991G SG 44991 G SG44991 G SG 44991G SG 44991 A SG44991 A SG 44991A SG 44991 A SG44991 A SG 44991A SG 44991 G SG44991 G SG 44991G
Authority
SG
Singapore
Prior art keywords
substituted derivatives
avermectin aglycones
aglycones
avermectin
derivatives
Prior art date
Application number
SG44991A
Other languages
English (en)
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SG44991G publication Critical patent/SG44991G/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Environmental Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
  • Fodder In General (AREA)
SG44991A 1985-02-25 1991-06-15 13-substituted derivatives of avermectin aglycones SG44991G (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/705,254 US4587247A (en) 1985-02-25 1985-02-25 Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use

Publications (1)

Publication Number Publication Date
SG44991G true SG44991G (en) 1991-07-26

Family

ID=24832670

Family Applications (1)

Application Number Title Priority Date Filing Date
SG44991A SG44991G (en) 1985-02-25 1991-06-15 13-substituted derivatives of avermectin aglycones

Country Status (9)

Country Link
US (1) US4587247A (fr)
EP (1) EP0193347B1 (fr)
JP (2) JP2509560B2 (fr)
AU (1) AU574566B2 (fr)
DE (1) DE3673664D1 (fr)
HK (1) HK62691A (fr)
NZ (1) NZ215186A (fr)
SG (1) SG44991G (fr)
ZA (1) ZA861351B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
ATE119905T1 (de) * 1985-09-13 1995-04-15 American Cyanamid Co Makrolide antibiotika und verfahren zu deren herstellung.
PH24180A (en) * 1986-03-12 1990-03-22 Glaxo Group Ltd Macrolide compounds,pharmaceutical composition containing said compound and method of use thereof
EP0240274A3 (fr) * 1986-04-03 1990-03-14 Merck & Co. Inc. Avermectine comme agents pour promotion de la croissance
US5019589A (en) * 1986-09-12 1991-05-28 American Cyanamid Company Δ23 -LL-F28249 compounds
US4918097A (en) * 1988-03-11 1990-04-17 Ciba-Geigy Corporation Insecticides and parasiticides
GB8811037D0 (en) * 1988-05-10 1988-06-15 Glaxo Group Ltd Chemical compounds
GB8917064D0 (en) * 1989-07-26 1989-09-13 Pfizer Ltd Antiparasitic agent
US5030650A (en) * 1989-09-11 1991-07-09 American Cyanamid Company 13-halo-23-imino derivatives of LL-F28249 compounds and their use as endo- and ectoparasiticidal, insecticidal, acaricidal and nematocidal agents
US5055454A (en) * 1989-10-30 1991-10-08 Merck & Co., Inc. 13-epi-avermectin derivatives useful as antiparasitic agents
US5114930A (en) * 1990-05-14 1992-05-19 Merck & Co., Inc. Avermectin derivatives with a spacer inserted between the disaccharide and the aglycone useful as antiparasitic agents
US5225338A (en) * 1990-09-24 1993-07-06 Merck & Co., Inc. Microbial preparation of 13β-13-deoxy-22,23-dihydro avermectin-B1A/B1B aglycone
EP0530901A1 (fr) * 1991-09-04 1993-03-10 Merck & Co. Inc. 13-bêta-O-méthoxyméthyl-22,23-dihydro avermectine B1A/B1B aglycone
US5229415A (en) * 1992-03-24 1993-07-20 Merck & Co., Inc. Alkylthio alkyl avermectins are active antiparasitic agents
PL174488B1 (pl) * 1993-05-10 1998-08-31 Merck & Co Inc Preparat do zwalczania pasożytów zwierząt oraz sposób wytwarzania preparatu do zwalczania pasożytów zwierząt
US5602107A (en) * 1993-05-10 1997-02-11 Merck & Co., Inc. Pour-on formulations consisting of gylcols, glycerides and avermectin compounds
BR9406594A (pt) * 1993-05-10 1996-01-02 Merck & Co Inc Formulação tópica e processos para sua preparação e para o tratamento e prevenção de parasitas internos e externos de animais
US5840324A (en) * 1993-05-26 1998-11-24 Commonwealth Scientific And Industrial Organisation Antiparasitic compositions
US5436355A (en) * 1994-02-03 1995-07-25 Merck & Co., Inc. Process for making avermectin/zein compositions
EP1849363A1 (fr) * 2006-03-09 2007-10-31 Cheminova A/S Combinations synergiques d'un plaguicide agoniste des canaux à chlorure actives par le glutamate ou le GABA et au moins un d'entre la vitamine E et la niacin
CA2684926C (fr) * 2007-05-03 2014-09-30 Merial Limited Compositions comprenant des composes alcoxyether macrolides c-13 et composes de phenylpyrazole
US7919522B2 (en) * 2007-05-03 2011-04-05 Merial Limited Compositions comprising C-13 alkoxyether macrolide compounds and phenylpyrazole compounds
JP5740676B2 (ja) * 2013-10-17 2015-06-24 メリアル リミテッド Ｃ−１３アルコキシエーテルマクロライド化合物及びフェニルピラゾール化合物を含む組成物
CN107337682B (zh) * 2016-11-22 2019-08-30 石家庄市兴柏生物工程有限公司 13-酰基化阿维菌素B2a苷元衍生物及其制备方法和用途

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950360A (en) * 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4093629A (en) * 1977-04-11 1978-06-06 Merck & Co., Inc. Derivatives of antibiotic substance milbemycin and processes therefor
US4134973A (en) * 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
US4173571A (en) * 1977-12-19 1979-11-06 Merck & Co., Inc. 13-Halo and 13-deoxy derivatives of C-076 compounds
US4171314A (en) * 1977-12-19 1979-10-16 Merck & Co., Inc. 13-Halo and 13-deoxy C-076 compounds
PH16612A (en) * 1977-12-19 1983-11-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds
US4200581A (en) * 1978-08-04 1980-04-29 Merck & Co., Inc. Alkyl derivatives of C-076 compounds
US4579864A (en) * 1984-06-11 1986-04-01 Merck & Co., Inc. Avermectin and milbemycin 13-keto, 13-imino and 13-amino derivatives
EP0180539A1 (fr) * 1984-09-18 1986-05-07 Ciba-Geigy Ag 13-Halo- et 13-hydroxymilbémycine
HUT39739A (en) * 1984-12-04 1986-10-29 Ciba Geigy Ag Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof
GB2168345B (en) * 1984-12-14 1988-05-25 Ciba Geigy Ag Pesticidal 13b-substituted milbemycin derivatives
US4857509A (en) * 1985-01-22 1989-08-15 Ciba-Geigy Corporation 13β-alkylmilbemycin derivatives for controlling parasites of animals and plants

Also Published As

Publication number Publication date
ZA861351B (en) 1986-10-29
US4587247A (en) 1986-05-06
JPH0873466A (ja) 1996-03-19
EP0193347B1 (fr) 1990-08-29
EP0193347A2 (fr) 1986-09-03
JP2509560B2 (ja) 1996-06-19
AU5400486A (en) 1986-08-28
DE3673664D1 (de) 1990-10-04
HK62691A (en) 1991-08-16
JPS61200993A (ja) 1986-09-05
NZ215186A (en) 1989-07-27
EP0193347A3 (en) 1986-10-29
JP2647361B2 (ja) 1997-08-27
AU574566B2 (en) 1988-07-07

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