SG43237A1 - Cloning of the biosynthetic pathway for chlortetracycline and tetracyline formation form streptomyces aureofaciens and its exptession in steptomyces lividans - Google Patents

Cloning of the biosynthetic pathway for chlortetracycline and tetracyline formation form streptomyces aureofaciens and its exptession in steptomyces lividans

Info

Publication number
SG43237A1
SG43237A1 SG1996006004A SG1996006004A SG43237A1 SG 43237 A1 SG43237 A1 SG 43237A1 SG 1996006004 A SG1996006004 A SG 1996006004A SG 1996006004 A SG1996006004 A SG 1996006004A SG 43237 A1 SG43237 A1 SG 43237A1
Authority
SG
Singapore
Prior art keywords
exptession
tetracyline
chlortetracycline
cloning
biosynthetic pathway
Prior art date
Application number
SG1996006004A
Other languages
English (en)
Inventor
Nancy Strathy
Michael J Ryan
Kason A Lotvin
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of SG43237A1 publication Critical patent/SG43237A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18Testing for antimicrobial activity of a material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P29/00Preparation of compounds containing a naphthacene ring system, e.g. tetracycline

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG1996006004A 1990-07-26 1991-07-27 Cloning of the biosynthetic pathway for chlortetracycline and tetracyline formation form streptomyces aureofaciens and its exptession in steptomyces lividans SG43237A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55803990A 1990-07-26 1990-07-26

Publications (1)

Publication Number Publication Date
SG43237A1 true SG43237A1 (en) 1997-10-17

Family

ID=24227935

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996006004A SG43237A1 (en) 1990-07-26 1991-07-27 Cloning of the biosynthetic pathway for chlortetracycline and tetracyline formation form streptomyces aureofaciens and its exptession in steptomyces lividans

Country Status (13)

Country Link
EP (1) EP0468220A3 (xx)
JP (1) JPH04346786A (xx)
KR (1) KR920002776A (xx)
AU (1) AU652766B2 (xx)
CA (1) CA2047833C (xx)
HU (1) HUT60771A (xx)
IE (1) IE912623A1 (xx)
IL (1) IL98684A0 (xx)
NZ (1) NZ239042A (xx)
PT (1) PT98428B (xx)
SG (1) SG43237A1 (xx)
TW (1) TW218893B (xx)
ZA (1) ZA915863B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE166391T1 (de) * 1990-07-26 1998-06-15 American Cyanamid Co Zur actinomyceten-dns-klonierung nützliches bifunktionelles cosmid
US5639949A (en) * 1990-08-20 1997-06-17 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
US5662898A (en) * 1990-08-20 1997-09-02 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
TW318189B (xx) * 1991-12-06 1997-10-21 American Cyanamid Co
US6495348B1 (en) 1993-10-07 2002-12-17 Regents Of The University Of Minnesota Mitomycin biosynthetic gene cluster
US6524812B1 (en) 1993-10-07 2003-02-25 Regents Of The University Of Minnesota Genes encoding resistance to DNA alkylating agents
US6117670A (en) * 1994-06-08 2000-09-12 Novartis Finance Corporation Pyrrolnitrin biosynthesis genes and uses thereof
US5989903A (en) * 1995-06-07 1999-11-23 American Cyanamid Company Strain for the production of 6-dimethyltetracycline, method for producing the strain and vector for use in the method
EP0870053A4 (en) 1995-12-19 2002-09-11 Univ Minnesota METABOLIC PROCESS FOR THE MANUFACTURE OF POLYHYDROXYALCANOATE MONOMER SYNTHASES
US6261842B1 (en) * 1997-10-23 2001-07-17 Wisconsin Alumni Research Foundation Microorganism genomics, compositions and methods related thereto
CA2330543A1 (en) * 1998-06-23 1999-12-29 Biosearch Italia S.P.A. Methods for transferring the capability to produce a natural product into a suitable production host
CN110129244B (zh) * 2019-01-23 2023-09-15 河北圣雪大成制药有限责任公司 链霉菌底盘菌株及其构建方法、在异源表达研究中的应用
CN109699495B (zh) * 2019-02-12 2022-04-08 云南农业大学 一种提高金毛狗脊孢子萌发率的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5098837A (en) * 1988-06-07 1992-03-24 Eli Lilly And Company Macrolide biosynthetic genes for use in streptomyces and other organisms
ATE166391T1 (de) * 1990-07-26 1998-06-15 American Cyanamid Co Zur actinomyceten-dns-klonierung nützliches bifunktionelles cosmid

Also Published As

Publication number Publication date
TW218893B (xx) 1994-01-11
IE912623A1 (en) 1992-01-29
IL98684A0 (en) 1992-07-15
PT98428B (pt) 1999-01-29
EP0468220A2 (en) 1992-01-29
PT98428A (pt) 1992-06-30
KR920002776A (ko) 1992-02-28
AU8134091A (en) 1992-01-30
CA2047833C (en) 2002-12-17
JPH04346786A (ja) 1992-12-02
EP0468220A3 (en) 1992-09-23
NZ239042A (en) 1993-09-27
HUT60771A (en) 1992-10-28
CA2047833A1 (en) 1992-01-27
ZA915863B (en) 1992-04-29
AU652766B2 (en) 1994-09-08
HU912500D0 (en) 1991-12-30

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