SG193437A1 - Scalable spectroscopic detection and measurement - Google Patents
Scalable spectroscopic detection and measurement Download PDFInfo
- Publication number
- SG193437A1 SG193437A1 SG2013068820A SG2013068820A SG193437A1 SG 193437 A1 SG193437 A1 SG 193437A1 SG 2013068820 A SG2013068820 A SG 2013068820A SG 2013068820 A SG2013068820 A SG 2013068820A SG 193437 A1 SG193437 A1 SG 193437A1
- Authority
- SG
- Singapore
- Prior art keywords
- light
- sample
- image sensor
- light source
- detection
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/42—Absorption spectrometry; Double beam spectrometry; Flicker spectrometry; Reflection spectrometry
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0208—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using focussing or collimating elements, e.g. lenses or mirrors; performing aberration correction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/021—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using plane or convex mirrors, parallel phase plates, or particular reflectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0216—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using light concentrators or collectors or condensers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
- G01J3/0248—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using a sighting port, e.g. camera or human eye
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/0291—Housings; Spectrometer accessories; Spatial arrangement of elements, e.g. folded path arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/06—Scanning arrangements arrangements for order-selection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/08—Beam switching arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/02—Details
- G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/12—Generating the spectrum; Monochromators
- G01J3/14—Generating the spectrum; Monochromators using refracting elements, e.g. prisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/12—Generating the spectrum; Monochromators
- G01J3/18—Generating the spectrum; Monochromators using diffraction elements, e.g. grating
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/2803—Investigating the spectrum using photoelectric array detector
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
- G01J3/4406—Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1434—Optical arrangements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1456—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
- G01N15/1459—Optical investigation techniques, e.g. flow cytometry without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
- G01N15/10—Investigating individual particles
- G01N15/14—Optical investigation techniques, e.g. flow cytometry
- G01N15/1484—Optical investigation techniques, e.g. flow cytometry microstructural devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/645—Specially adapted constructive features of fluorimeters
- G01N21/6456—Spatial resolved fluorescence measurements; Imaging
Landscapes
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Pathology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161469889P | 2011-03-31 | 2011-03-31 | |
| PCT/US2012/030716 WO2012135201A1 (en) | 2011-03-31 | 2012-03-27 | Scalable spectroscopic detection and measurement |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG193437A1 true SG193437A1 (en) | 2013-10-30 |
Family
ID=46931881
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013068820A SG193437A1 (en) | 2011-03-31 | 2012-03-27 | Scalable spectroscopic detection and measurement |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9228898B2 (enExample) |
| EP (1) | EP2691752A4 (enExample) |
| JP (1) | JP5986623B2 (enExample) |
| CN (1) | CN103582805B (enExample) |
| AU (1) | AU2012236748B2 (enExample) |
| CA (1) | CA2841425C (enExample) |
| SG (1) | SG193437A1 (enExample) |
| WO (1) | WO2012135201A1 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2820094C (en) | 2010-12-07 | 2019-02-26 | Gnubio, Inc. | Nucleic acid target detection using fluorophore- and quencher-conjugated oligonucleotides |
| JP6472998B2 (ja) | 2011-03-30 | 2019-02-20 | バイオ−ラッド ラボラトリーズ インコーポレイテッド | 液滴内への、または液滴からの複数の容量の注入 |
| WO2012135201A1 (en) | 2011-03-31 | 2012-10-04 | Gnubio, Inc. | Scalable spectroscopic detection and measurement |
| EP2691540B1 (en) | 2011-03-31 | 2016-01-20 | GnuBIO, Inc. | Managing variation in spectroscopic intensity measurements through the use of a reference component |
| US9821312B2 (en) | 2012-09-12 | 2017-11-21 | Bio-Rad Laboratories, Inc. | Integrated microfluidic system, method and kit for performing assays |
| US9291503B2 (en) * | 2012-11-08 | 2016-03-22 | Hitachi, Ltd. | Flow type single-particle spectrometer |
| US9592503B2 (en) | 2013-01-25 | 2017-03-14 | Gnubio, Inc. | System and method for performing droplet inflation |
| EP3004813A4 (en) | 2013-05-29 | 2016-12-21 | Gnubio Inc | COST-EFFECTIVE OPTICAL DISCRETE HIGH-SPEED MEASURING SYSTEM |
| EP3004391B1 (en) | 2013-05-29 | 2019-03-27 | Bio-Rad Laboratories, Inc. | Methods for sequencing in emulsion based microfluidics |
| CN105765055A (zh) | 2013-08-27 | 2016-07-13 | 基纽拜奥股份有限公司 | 微流体装置和其使用方法 |
| EP3052236B1 (en) | 2013-09-30 | 2021-07-14 | Bio-Rad Laboratories, Inc. | Microfluidic cartridge device and methods of use and assembly |
| US10130950B2 (en) | 2013-11-27 | 2018-11-20 | Bio-Rad Laboratories, Inc. | Microfluidic droplet packing |
| US9869664B2 (en) * | 2013-12-18 | 2018-01-16 | Saudi Arabian Oil Company | Method for non-intrusive measurement of low water content in oil |
| US9683792B2 (en) | 2014-06-30 | 2017-06-20 | Bio-Rad Laboratories, Inc. | Floating thermal contact enabled PCR |
| GB201415238D0 (en) * | 2014-08-28 | 2014-10-15 | Renishaw Plc | Spectroscopy apparatus |
| TWI544210B (zh) * | 2014-10-21 | 2016-08-01 | 王基旆 | 可攜式電子裝置、結合該裝置之光譜儀及利用該裝置檢測物品品質之方法 |
| US10215771B2 (en) | 2014-11-06 | 2019-02-26 | Bio-Rad Laboratories, Inc. | Droplet velocity detection |
| CN104483104B (zh) * | 2014-12-25 | 2018-01-12 | 中国科学院半导体研究所 | 一种光电探测器光谱响应分析系统 |
| KR20240116531A (ko) | 2015-02-09 | 2024-07-29 | 슬링샷 바이오사이언시즈 인코포레이티드 | 튜닝가능한 광 특성을 갖는 하이드로겔 입자 및 이를 사용하기 위한 방법 |
| CN107250762B (zh) * | 2015-03-06 | 2020-06-30 | 贝克顿·迪金森公司 | 集光系统及其制造和使用方法 |
| CN107923070A (zh) | 2015-08-25 | 2018-04-17 | 生物辐射实验室股份有限公司 | 数字式免疫测定 |
| US10386284B2 (en) * | 2016-01-29 | 2019-08-20 | JianFeng Zhang | Device and method for measurement of dispersed objects using fluorescent and non-fluorescent imaging with laser |
| WO2017180699A1 (en) | 2016-04-14 | 2017-10-19 | Saudi Arabian Oil Company | Characterizing petroleum product contamination using fluorescence signal |
| WO2017180704A1 (en) | 2016-04-14 | 2017-10-19 | Saudi Arabian Oil Company | Opto-mechanical part for parabolic mirror fine rotation and on-axis linear positioning |
| WO2017189603A1 (en) | 2016-04-26 | 2017-11-02 | Saudi Arabian Oil Company | Characterizing lubricant oil degradation using fluorescence signals |
| CN109557015B (zh) * | 2016-11-01 | 2021-05-25 | 北京信息科技大学 | 流式细胞仪光谱重叠信号数字处理方法 |
| JP6784603B2 (ja) * | 2017-01-05 | 2020-11-11 | 東レエンジニアリング株式会社 | 分光測定方法および分光測定装置 |
| EP3747985A4 (en) * | 2018-02-01 | 2021-10-27 | Agc Inc. | CELL CULTURE CONTAINER |
| CN111742212B (zh) | 2019-01-08 | 2024-02-20 | 京东方科技集团股份有限公司 | 流体检测面板和流体检测装置 |
| CN109632660B (zh) * | 2019-01-17 | 2022-04-05 | 京东方科技集团股份有限公司 | 流体检测面板 |
| CN114829626A (zh) | 2019-10-10 | 2022-07-29 | 1859公司 | 用于微流体筛选的方法和系统 |
| EP4094064A4 (en) | 2020-01-24 | 2024-02-28 | Slingshot Biosciences, Inc. | Compositions and methods for cell-like calibration particles |
| KR20230029612A (ko) | 2020-05-04 | 2023-03-03 | 슬링샷 바이오사이언시즈 인코포레이티드 | 다중 검정을 위한 수동 광학 바코딩용 조성물 및 방법 |
| WO2022140291A1 (en) * | 2020-12-21 | 2022-06-30 | Singular Genomics Systems, Inc. | Systems and methods for multicolor imaging |
| CN113155287B (zh) * | 2021-04-27 | 2022-10-21 | 江苏汇鼎光学眼镜有限公司 | 一种眼镜片测色装置 |
| CA3235582A1 (en) | 2021-10-29 | 2023-05-04 | Anh Tuan Nguyen | Hydrogel particles as feeder cells and as synthetic antigen presenting cells |
| US12259377B2 (en) | 2022-04-05 | 2025-03-25 | Saudi Arabian Oil Company | Detecting hydrocarbon fuels in lubrication oils |
| EP4519690A1 (en) | 2022-05-05 | 2025-03-12 | Slingshot Biosciences, Inc. | Engineered particles as red blood cell mimics and compositions containing same for hematology |
| US12216041B2 (en) | 2022-05-31 | 2025-02-04 | Saudi Arabian Oil Company | Method to detect diesel in fluid samples using partially dissolvable cuvettes |
| KR20250025383A (ko) | 2022-06-02 | 2025-02-21 | 슬링샷 바이오사이언시즈 인코포레이티드 | 아폽토시스 세포 모방체 |
| CN120712108A (zh) | 2022-10-26 | 2025-09-26 | 弹弓生物科学公司 | 具有可调整光学性质的大小可调整合成颗粒和用于使用其进行免疫细胞激活的方法 |
| US12298266B2 (en) | 2023-03-30 | 2025-05-13 | Saudi Arabian Oil Company | Changes in resistivity of mesh-patterned polymer thin films coated with conductive traces used to detect hydrocarbon fuels hidden in paraffin-based lubrication oils |
| WO2025049609A1 (en) | 2023-08-29 | 2025-03-06 | Slingshot Biosciences, Inc. | Cd34 stem cell mimics |
| DE102023131464A1 (de) * | 2023-11-13 | 2025-05-15 | Fluidect Gmbh | Detektionssystem und Verfahren zum Erfassen einer elektromagnetischen Emission von Mikropartikeln |
Family Cites Families (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2975669A (en) | 1954-08-26 | 1961-03-21 | Jarrell Ash Company | Crossed dispersion photographic spectrometer |
| US5159199A (en) | 1991-08-12 | 1992-10-27 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Integrated filter and detector array for spectral imaging |
| US5206701A (en) * | 1991-09-20 | 1993-04-27 | Amoco Corporation | Apparatus for near-infrared spectrophotometric analysis |
| US5434629A (en) | 1993-12-20 | 1995-07-18 | Focus Automation Systems Inc. | Real-time line scan processor |
| US5610771A (en) | 1994-08-01 | 1997-03-11 | Lockheed Missiles & Space Company, Inc. | Non-deviating prism with continuously variable dispersion |
| US6017434A (en) | 1995-05-09 | 2000-01-25 | Curagen Corporation | Apparatus and method for the generation, separation, detection, and recognition of biopolymer fragments |
| US6982431B2 (en) * | 1998-08-31 | 2006-01-03 | Molecular Devices Corporation | Sample analysis systems |
| US6043881A (en) * | 1998-03-06 | 2000-03-28 | Praxair Technology Inc | Sample cell for gaseous emission spectroscopy |
| US7079241B2 (en) | 2000-04-06 | 2006-07-18 | Invitrogen Corp. | Spatial positioning of spectrally labeled beads |
| US6975400B2 (en) * | 1999-01-25 | 2005-12-13 | Amnis Corporation | Imaging and analyzing parameters of small moving objects such as cells |
| US6875973B2 (en) * | 2000-08-25 | 2005-04-05 | Amnis Corporation | Auto focus for a flow imaging system |
| WO2002101339A2 (en) * | 2000-10-12 | 2002-12-19 | Amnis Corporation | Imaging and analyzing parameters of small moving objects such as cells |
| US6856390B2 (en) * | 2001-07-25 | 2005-02-15 | Applera Corporation | Time-delay integration in electrophoretic detection systems |
| US6831688B2 (en) * | 2002-04-08 | 2004-12-14 | Recon/Optical, Inc. | Multispectral or hyperspectral imaging system and method for tactical reconnaissance |
| JP2006520900A (ja) | 2003-03-11 | 2006-09-14 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 励起システム及び焦点モニタリングシステムを備える分光分析装置及び方法 |
| EP2662136A3 (en) | 2003-08-27 | 2013-12-25 | President and Fellows of Harvard College | Method for handling and mixing droplets |
| CA2504817A1 (en) | 2004-04-21 | 2005-10-21 | University Technologies International Inc. | Synchronization of time delay and integration cameras |
| US7046359B2 (en) | 2004-06-30 | 2006-05-16 | Chemimage Corporation | System and method for dynamic chemical imaging |
| JP4982385B2 (ja) * | 2005-02-01 | 2012-07-25 | アムニス コーポレイション | イメージングフローサイトメータを使用した血液及び細胞の分析 |
| WO2006110135A1 (en) | 2005-04-08 | 2006-10-19 | Chemimage Corporation | System and method for chemical imaging of microarrays |
| EP3913375A1 (en) | 2006-01-11 | 2021-11-24 | Bio-Rad Laboratories, Inc. | Microfluidic devices and methods of use in the formation and control of nanoreactors |
| US7815871B2 (en) * | 2006-04-18 | 2010-10-19 | Advanced Liquid Logic, Inc. | Droplet microactuator system |
| EP2021113A2 (en) | 2006-05-11 | 2009-02-11 | Raindance Technologies, Inc. | Microfluidic devices |
| GB0611981D0 (en) | 2006-06-16 | 2006-07-26 | Renishaw Plc | Spectroscopic analysis methods |
| US8179526B2 (en) * | 2007-01-25 | 2012-05-15 | Renishaw Plc | Spectroscopic apparatus with dispersive device for collecting sample data in synchronism with relative movement of a focus |
| US9797010B2 (en) | 2007-12-21 | 2017-10-24 | President And Fellows Of Harvard College | Systems and methods for nucleic acid sequencing |
| EP2286125B1 (en) | 2008-05-16 | 2015-07-08 | President and Fellows of Harvard College | Valves and other flow control in fluidic systems including microfluidic systems |
| WO2010033200A2 (en) | 2008-09-19 | 2010-03-25 | President And Fellows Of Harvard College | Creation of libraries of droplets and related species |
| EP3290531B1 (en) | 2008-12-19 | 2019-07-24 | President and Fellows of Harvard College | Particle-assisted nucleic acid sequencing |
| US8047829B1 (en) | 2009-01-26 | 2011-11-01 | Sandia Corporation | Method for forming polymerized microfluidic devices |
| WO2010111231A1 (en) | 2009-03-23 | 2010-09-30 | Raindance Technologies, Inc. | Manipulation of microfluidic droplets |
| JP5841937B2 (ja) | 2009-06-26 | 2016-01-13 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 流体注入 |
| EP2493619B1 (en) | 2009-10-27 | 2018-12-19 | President and Fellows of Harvard College | Droplet creation techniques |
| EP4484577A3 (en) | 2010-02-12 | 2025-03-26 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| CA2820094C (en) | 2010-12-07 | 2019-02-26 | Gnubio, Inc. | Nucleic acid target detection using fluorophore- and quencher-conjugated oligonucleotides |
| WO2012109600A2 (en) | 2011-02-11 | 2012-08-16 | Raindance Technologies, Inc. | Methods for forming mixed droplets |
| US9150852B2 (en) | 2011-02-18 | 2015-10-06 | Raindance Technologies, Inc. | Compositions and methods for molecular labeling |
| JP6472998B2 (ja) | 2011-03-30 | 2019-02-20 | バイオ−ラッド ラボラトリーズ インコーポレイテッド | 液滴内への、または液滴からの複数の容量の注入 |
| WO2012135201A1 (en) | 2011-03-31 | 2012-10-04 | Gnubio, Inc. | Scalable spectroscopic detection and measurement |
| EP2691540B1 (en) | 2011-03-31 | 2016-01-20 | GnuBIO, Inc. | Managing variation in spectroscopic intensity measurements through the use of a reference component |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| US11389800B2 (en) | 2011-09-28 | 2022-07-19 | President And Fellows Of Harvard College | Systems and methods for droplet production and/or fluidic manipulation |
| US20150045258A1 (en) | 2012-02-14 | 2015-02-12 | Gnubio, Inc. | Cascaded addition of target specific universal adapters to nucleic acids |
| WO2013165748A1 (en) | 2012-04-30 | 2013-11-07 | Raindance Technologies, Inc | Digital analyte analysis |
| US9821312B2 (en) | 2012-09-12 | 2017-11-21 | Bio-Rad Laboratories, Inc. | Integrated microfluidic system, method and kit for performing assays |
| US20150321163A1 (en) | 2012-12-14 | 2015-11-12 | Gnubio, Inc. | Method for maintaining heterogeneous concentrations of molecules in emulsion droplets |
| US9592503B2 (en) | 2013-01-25 | 2017-03-14 | Gnubio, Inc. | System and method for performing droplet inflation |
| EP2989213B1 (en) | 2013-04-26 | 2019-11-06 | Bio-Rad Laboratories, Inc. | A method for blocking polymerase extension of 3 prime dna ends by stem-loop structure |
| EP3004391B1 (en) | 2013-05-29 | 2019-03-27 | Bio-Rad Laboratories, Inc. | Methods for sequencing in emulsion based microfluidics |
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2012
- 2012-03-27 WO PCT/US2012/030716 patent/WO2012135201A1/en not_active Ceased
- 2012-03-27 EP EP12765764.1A patent/EP2691752A4/en not_active Withdrawn
- 2012-03-27 CA CA2841425A patent/CA2841425C/en active Active
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| EP2691752A4 (en) | 2014-09-17 |
| WO2012135201A1 (en) | 2012-10-04 |
| CN103582805B (zh) | 2016-08-10 |
| CA2841425C (en) | 2018-05-01 |
| US20140198313A1 (en) | 2014-07-17 |
| CA2841425A1 (en) | 2012-10-04 |
| JP5986623B2 (ja) | 2016-09-06 |
| US9228898B2 (en) | 2016-01-05 |
| CN103582805A (zh) | 2014-02-12 |
| AU2012236748A1 (en) | 2013-10-03 |
| AU2012236748B2 (en) | 2015-11-26 |
| JP2014512532A (ja) | 2014-05-22 |
| EP2691752A1 (en) | 2014-02-05 |
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