SG185946A1 - Novel neurturin conjugates for pharmaceutical use - Google Patents
Novel neurturin conjugates for pharmaceutical use Download PDFInfo
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- SG185946A1 SG185946A1 SG2012081220A SG2012081220A SG185946A1 SG 185946 A1 SG185946 A1 SG 185946A1 SG 2012081220 A SG2012081220 A SG 2012081220A SG 2012081220 A SG2012081220 A SG 2012081220A SG 185946 A1 SG185946 A1 SG 185946A1
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- neurturin
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- protein product
- human
- polyethylene glycol
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
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- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/02—Peptides being immobilised on, or in, an organic carrier
- C07K17/08—Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Public Health (AREA)
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- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07021493 | 2007-11-05 |
Publications (1)
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| SG185946A1 true SG185946A1 (en) | 2012-12-28 |
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| SG2012081220A SG185946A1 (en) | 2007-11-05 | 2008-11-05 | Novel neurturin conjugates for pharmaceutical use |
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| US (3) | US9029323B2 (https=) |
| EP (1) | EP2217282A2 (https=) |
| JP (2) | JP2011503019A (https=) |
| KR (2) | KR20150139982A (https=) |
| CN (2) | CN101848735B (https=) |
| AU (1) | AU2008324426B2 (https=) |
| BR (1) | BRPI0819220A2 (https=) |
| CA (1) | CA2742839A1 (https=) |
| CO (1) | CO6280503A2 (https=) |
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| EA (1) | EA201070484A1 (https=) |
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| MX (1) | MX2010004899A (https=) |
| NZ (1) | NZ585262A (https=) |
| SG (1) | SG185946A1 (https=) |
| WO (1) | WO2009059755A2 (https=) |
| ZA (1) | ZA201003227B (https=) |
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| US20050222070A1 (en) | 2002-05-29 | 2005-10-06 | Develogen Aktiengesellschaft Fuer Entwicklungsbiologische Forschung | Pancreas-specific proteins |
| JP4838724B2 (ja) | 2003-11-27 | 2011-12-14 | デヴェロゲン アクチエンゲゼルシャフト | ニュールツリンを用いる糖尿病の予防と治療方法 |
| US8445432B2 (en) | 2009-10-30 | 2013-05-21 | Ntf Therapeutics Inc | Neurturin molecules |
| US9127083B2 (en) | 2009-10-30 | 2015-09-08 | Ntf Therapeutics, Inc. | Neurturin molecules |
| NZ599543A (en) * | 2009-10-30 | 2014-02-28 | Ntf Therapeutics Inc | Improved neurturin molecules |
| US8742677B2 (en) * | 2010-01-11 | 2014-06-03 | System General Corp. | LED drive circuit with a programmable input for LED lighting |
| CN102453725B (zh) * | 2010-11-02 | 2014-06-11 | 杭州纽龙生物科技有限公司 | 一种重组载体、包含该重组载体的重组菌株及制备方法 |
| JP6051378B2 (ja) | 2011-05-02 | 2016-12-27 | 国立大学法人 熊本大学 | 幹細胞からインスリン産生細胞への分化誘導を促進する低分子化合物および該化合物を用いた幹細胞からインスリン産生細胞への分化誘導方法 |
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| US5739307A (en) * | 1995-08-28 | 1998-04-14 | Washington University | Polynucleotide encoding neurturin neurotrophic factor |
| US6043221A (en) * | 1997-07-30 | 2000-03-28 | Amgen Inc. | Method for preventing and treating hearing loss using a neuturin protein product |
| CA2344277A1 (en) * | 1998-09-22 | 2000-03-30 | University Of Maryland, Baltimore | Cystine knot growth factor mutants |
| US7442370B2 (en) * | 2001-02-01 | 2008-10-28 | Biogen Idec Ma Inc. | Polymer conjugates of mutated neublastin |
| US20050222070A1 (en) * | 2002-05-29 | 2005-10-06 | Develogen Aktiengesellschaft Fuer Entwicklungsbiologische Forschung | Pancreas-specific proteins |
| AU2003238178A1 (en) | 2002-05-29 | 2003-12-12 | Develogen Aktiengesellschaft Fur Entwicklungsbiologische Forschung | Pancreas-specific proteins |
| WO2005039643A2 (en) * | 2003-10-20 | 2005-05-06 | Nsgene A/S | In vivo gene therapy of parkinson's disease |
| JP4838724B2 (ja) * | 2003-11-27 | 2011-12-14 | デヴェロゲン アクチエンゲゼルシャフト | ニュールツリンを用いる糖尿病の予防と治療方法 |
| EP1872790A1 (en) * | 2006-06-26 | 2008-01-02 | DeveloGen Aktiengesellschaft | New formulation for increasing bioavailability of neurturin |
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2008
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- 2008-11-05 EP EP08848146A patent/EP2217282A2/en not_active Withdrawn
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- 2008-11-05 BR BRPI0819220-0A patent/BRPI0819220A2/pt not_active IP Right Cessation
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2010
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2013
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2015
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Also Published As
| Publication number | Publication date |
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| AU2008324426A1 (en) | 2009-05-14 |
| US9029323B2 (en) | 2015-05-12 |
| AU2008324426B2 (en) | 2014-03-27 |
| WO2009059755A2 (en) | 2009-05-14 |
| KR20100098619A (ko) | 2010-09-08 |
| JP2011503019A (ja) | 2011-01-27 |
| WO2009059755A3 (en) | 2009-09-24 |
| EP2217282A2 (en) | 2010-08-18 |
| CO6280503A2 (es) | 2011-05-20 |
| ZA201003227B (en) | 2011-03-30 |
| US20160060317A1 (en) | 2016-03-03 |
| JP2015057384A (ja) | 2015-03-26 |
| KR20150139982A (ko) | 2015-12-14 |
| US20110003741A1 (en) | 2011-01-06 |
| CN101848735A (zh) | 2010-09-29 |
| BRPI0819220A2 (pt) | 2019-02-26 |
| CN101848735B (zh) | 2014-07-23 |
| IL205290A (en) | 2014-01-30 |
| IL205290A0 (en) | 2010-12-30 |
| CR11406A (es) | 2010-10-25 |
| US20130231283A1 (en) | 2013-09-05 |
| CN104288775A (zh) | 2015-01-21 |
| CA2742839A1 (en) | 2009-05-14 |
| EA201070484A1 (ru) | 2011-04-29 |
| NZ585262A (en) | 2012-06-29 |
| MX2010004899A (es) | 2010-09-07 |
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