SG175568A1 - Photochemical therapy to affect mechanical and/or chemical properties of body tissue - Google Patents

Photochemical therapy to affect mechanical and/or chemical properties of body tissue Download PDF

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Publication number
SG175568A1
SG175568A1 SG2011070554A SG2011070554A SG175568A1 SG 175568 A1 SG175568 A1 SG 175568A1 SG 2011070554 A SG2011070554 A SG 2011070554A SG 2011070554 A SG2011070554 A SG 2011070554A SG 175568 A1 SG175568 A1 SG 175568A1
Authority
SG
Singapore
Prior art keywords
photoinitiator
tissue
ocular
compound
myopia
Prior art date
Application number
SG2011070554A
Other languages
English (en)
Inventor
Daniel M Schwartz
Matthew S Mattson
Julia A Kornfield
Robert K Maloney
Robert H Grubbs
Original Assignee
California Inst Of Techn
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Inst Of Techn, Univ California filed Critical California Inst Of Techn
Publication of SG175568A1 publication Critical patent/SG175568A1/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/0079Methods or devices for eye surgery using non-laser electromagnetic radiation, e.g. non-coherent light or microwaves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts or implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F2009/00861Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00865Sclera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F2009/00861Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00872Cornea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F2009/00885Methods or devices for eye surgery using laser for treating a particular disease
    • A61F2009/00893Keratoconus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electromagnetism (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG2011070554A 2006-10-24 2007-10-24 Photochemical therapy to affect mechanical and/or chemical properties of body tissue SG175568A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US85394906P 2006-10-24 2006-10-24
US95454107P 2007-08-07 2007-08-07

Publications (1)

Publication Number Publication Date
SG175568A1 true SG175568A1 (en) 2011-11-28

Family

ID=39325405

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2011070554A SG175568A1 (en) 2006-10-24 2007-10-24 Photochemical therapy to affect mechanical and/or chemical properties of body tissue

Country Status (5)

Country Link
US (1) US8414911B2 (https=)
JP (1) JP5559540B2 (https=)
KR (2) KR101502632B1 (https=)
SG (1) SG175568A1 (https=)
WO (1) WO2008052081A2 (https=)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100266989A1 (en) 2006-11-09 2010-10-21 Klox Technologies Inc. Teeth whitening compositions and methods
WO2008124009A2 (en) * 2007-04-02 2008-10-16 The Cleveland Clinic Foundation Treating glaucoma
US8545487B2 (en) * 2007-12-05 2013-10-01 Avedro Inc. Eye therapy system
CZ18420U1 (cs) * 2008-01-25 2008-04-07 Benedík@Jaroslav Prístroj na zjištování kvality a pevnosti cévní steny
JP2011514359A (ja) * 2008-03-14 2011-05-06 ユークリッド システムズ コーポレイション 角膜脆弱性疾患を治療するための紫外線の照射
GB0816399D0 (en) * 2008-09-09 2008-10-15 Sharma Anant Irradiation treatment
US8366689B2 (en) * 2008-09-30 2013-02-05 Avedro, Inc. Method for making structural changes in corneal fibrils
PL2352488T3 (pl) 2008-11-07 2017-07-31 Klox Technologies Inc. Utleniająca, aktywowana światłem kompozycja do odmładzania skóry zawierająca kwas hialuronowy, glukozaminę lub alantoinę
HUE035716T2 (en) 2009-07-17 2018-05-28 Klox Tech Inc Antibacterial oral composition
US20110077468A1 (en) * 2009-09-30 2011-03-31 Finger Paul T Drug eluting eyelid speculum
WO2011050164A1 (en) 2009-10-21 2011-04-28 Avedro, Inc. Eye therapy
DE102010008146B4 (de) 2010-02-12 2022-03-31 Carl Zeiss Meditec Ag Messsystem und Verfahren zum Ermitteln des Innendrucks eines Auges sowie Verfahren und System zum Einstellen des Augeninnendrucks
US20110237999A1 (en) * 2010-03-19 2011-09-29 Avedro Inc. Systems and methods for applying and monitoring eye therapy
DE102010020194B4 (de) 2010-05-07 2022-09-08 Carl Zeiss Meditec Ag Vorrichtung zur Stabilisierung der Augenhornhaut
US9622911B2 (en) 2010-09-30 2017-04-18 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
US20120310141A1 (en) * 2011-05-06 2012-12-06 Kornfield Julia A Light delivery device and related compositions, methods and systems
US9044308B2 (en) 2011-05-24 2015-06-02 Avedro, Inc. Systems and methods for reshaping an eye feature
WO2012167260A2 (en) 2011-06-02 2012-12-06 Avedro, Inc. Systems and methods for monitoring time based photo active agent delivery or photo active marker presence
IN2014CN02153A (https=) 2011-08-23 2015-05-29 Yeda Res & Dev
WO2013149075A1 (en) 2012-03-29 2013-10-03 Cxl Ophthalmics, Llc Compositions and methods for treating or preventing diseases associated with oxidative stress
EP4420725A3 (en) 2012-03-29 2025-04-16 Epion Therapeutics, Inc. Ocular treatment solutions, delivery devices and delivery augmentation methods
US9555111B2 (en) 2012-03-29 2017-01-31 Cxl Ophthalmics, Llc Ocular cross-linking system and method for sealing corneal wounds
US11116841B2 (en) 2012-04-20 2021-09-14 Klox Technologies Inc. Biophotonic compositions, kits and methods
US20130281913A1 (en) 2012-04-20 2013-10-24 Klox Technologies Inc. Biophotonic compositions and methods for providing biophotonic treatment
WO2013059837A2 (en) 2012-07-16 2013-04-25 Avedro, Inc. Systems and methods for corneal cross-linking with pulsed light
KR20150082189A (ko) 2012-09-14 2015-07-15 밸리언트 파마슈티컬즈 인터내셔널, 인코퍼레이션 치아미백용 조성물 및 치아미백 방법
DE102013004482A1 (de) 2013-03-12 2014-09-18 Carl Zeiss Meditec Ag Vorrichtung und Verfahren zur Stabilisierung der Augenhornhaut
EP2967986A4 (en) * 2013-03-14 2016-11-16 Cxl Ophthalmics Llc EYE TREATMENT DEVICE, SYSTEM AND METHOD OF USE
US20140276354A1 (en) 2013-03-14 2014-09-18 Klox Technologies Inc. Biophotonic materials and uses thereof
US9498114B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
WO2014205145A1 (en) 2013-06-18 2014-12-24 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
HK1219890A1 (zh) 2013-07-03 2017-04-21 广东科洛克生物医药集团有限公司 治疗不癒合伤口的组合物和方法
US9920147B2 (en) 2013-09-13 2018-03-20 Brandeis University Polymeric materials having active cross-linkers, methods for making them, and use thereof
JP2017509433A (ja) 2014-04-01 2017-04-06 クロックス テクノロジーズ インコーポレイテッドKlox Technologies Inc. 組織充填剤組成物および使用方法
KR102416876B1 (ko) 2014-10-27 2022-07-05 아베드로 인코퍼레이티드 눈의 교차-결합 처리를 위한 시스템 및 방법
ES2856841T3 (es) 2014-10-31 2021-09-28 Klox Tech Inc Fibras y medios de tela fotoactivables
US10114205B2 (en) 2014-11-13 2018-10-30 Avedro, Inc. Multipass virtually imaged phased array etalon
EP3285704B1 (en) 2015-04-24 2020-11-18 Avedro Inc. Systems for photoactivating a photosensitizer applied to an eye
CA2985368A1 (en) 2015-05-14 2016-11-17 California Institute Of Technology Light adjustable intraocular lenses using upconverting nanoparticles and near infrared (nir) light
US10028657B2 (en) 2015-05-22 2018-07-24 Avedro, Inc. Systems and methods for monitoring cross-linking activity for corneal treatments
US11207410B2 (en) 2015-07-21 2021-12-28 Avedro, Inc. Systems and methods for treatments of an eye with a photosensitizer
US10646372B2 (en) 2015-12-03 2020-05-12 Avedro, Inc. Systems and methods for treating an eye with a mask device
DE102016208012A1 (de) 2016-05-10 2017-11-16 Carl Zeiss Meditec Ag Augenchirurgisches Verfahren
WO2019005943A1 (en) 2017-06-28 2019-01-03 California Institute Of Technology LIGHT ADJUSTABLE INTRAOCULAR LENSES USING ASCENDING CONVERSION OF HEART-WOOD NANOPARTICLES AND INFRARED NEAR-LIGHT (NIR)
EP4397287A3 (en) 2018-03-05 2024-09-11 Avedro, Inc. System for eye tracking during eye treatment
WO2019173762A1 (en) 2018-03-08 2019-09-12 Avedro, Inc. Micro-devices for treatment of an eye
CN113329723A (zh) 2018-09-19 2021-08-31 艾维德洛公司 治疗角膜扩张型疾病的系统和方法
CN113316411B (zh) 2018-09-19 2025-01-17 艾维德洛公司 用于眼部治疗期间的眼部追踪的系统及方法
EP3863576A4 (en) 2018-10-09 2022-07-06 Avedro, Inc. PHOTOACTIVATION SYSTEMS AND METHODS FOR CORNEAL CROSSLINKING TREATMENT
US11702546B2 (en) 2018-10-24 2023-07-18 California Institute Of Technology Near-infrared heptamethine dyes for generation of singlet oxygen
CN111140774B (zh) * 2019-01-31 2025-10-14 中国科学院昆明动物研究所 一种可抑制眼轴过度增长的新型光源及其模拟方法、灯具
JP7571038B2 (ja) 2019-02-26 2024-10-22 アヴェドロ・インコーポレーテッド 眼の架橋処置のためのシステム及び方法
JP6853446B2 (ja) * 2019-02-28 2021-03-31 地方独立行政法人神奈川県立産業技術総合研究所 流動体試料の内部構造観察装置及び内部構造解析システム、流動体試料の内部構造観察方法及び内部構造解析方法、並びにセラミックスの製造方法
US11298263B2 (en) * 2019-07-16 2022-04-12 Jack T. Holladay Method of mitigating myopia development and related instrumentation
JP7624433B2 (ja) 2019-08-06 2025-01-30 アヴェドロ・インコーポレーテッド 角膜の架橋治療のための光活性化システム及び方法
WO2022192237A1 (en) 2021-03-08 2022-09-15 Avedro, Inc. Systems and methods for generating patient-specific corneal cross-linking treatment patterns
DE102021131244A1 (de) * 2021-11-29 2023-06-01 Philipps-Universität Marburg, Körperschaft des öffentlichen Rechts Orts- und zeitaufgelöste Bestimmung der dermalen Penetration von nicht- oder schwachfluoreszierenden Substanzen
WO2025255364A1 (en) * 2024-06-07 2025-12-11 The Regents Of The University Of California Methods and devices for transscleral multiphoton imaging and laser therapy

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6161544A (en) * 1998-01-28 2000-12-19 Keratoform, Inc. Methods for accelerated orthokeratology
JP2002058695A (ja) * 1999-09-03 2002-02-26 Carl Zeiss Jena Gmbh 眼の照射方法及び装置
US7727544B2 (en) * 2004-05-07 2010-06-01 The Regents Of The University Of California Treatment of myopia
US20060276777A1 (en) * 2005-04-08 2006-12-07 Coroneo Minas T Corneal shaping
WO2007001926A2 (en) 2005-06-24 2007-01-04 Hyperbranch Medical Technology, Inc. Low-swelling hydrogel sealants for wound repair

Also Published As

Publication number Publication date
WO2008052081A3 (en) 2008-06-19
US8414911B2 (en) 2013-04-09
WO2008052081A8 (en) 2008-08-14
KR20090082392A (ko) 2009-07-30
WO2008052081A2 (en) 2008-05-02
KR20140096371A (ko) 2014-08-05
KR101551590B1 (ko) 2015-09-08
JP5559540B2 (ja) 2014-07-23
JP2010507686A (ja) 2010-03-11
US20080114283A1 (en) 2008-05-15
KR101502632B1 (ko) 2015-03-17

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