SG155923A1 - Fluorescent dye compounds, conjugates and uses thereof - Google Patents
Fluorescent dye compounds, conjugates and uses thereofInfo
- Publication number
- SG155923A1 SG155923A1 SG200906144-1A SG2009061441A SG155923A1 SG 155923 A1 SG155923 A1 SG 155923A1 SG 2009061441 A SG2009061441 A SG 2009061441A SG 155923 A1 SG155923 A1 SG 155923A1
- Authority
- SG
- Singapore
- Prior art keywords
- conjugates
- fluorescent dye
- dye compounds
- fluorescent dyes
- dyes
- Prior art date
Links
- 239000007850 fluorescent dye Substances 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B15/00—Acridine dyes
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
- C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1003—Carbocyclic compounds
- C09K2211/1011—Condensed systems
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1018—Heterocyclic compounds
- C09K2211/1025—Heterocyclic compounds characterised by ligands
- C09K2211/1029—Heterocyclic compounds characterised by ligands containing one nitrogen atom as the heteroatom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Materials Engineering (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61111904P | 2004-09-16 | 2004-09-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG155923A1 true SG155923A1 (en) | 2009-10-29 |
Family
ID=35455743
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG200906144-1A SG155923A1 (en) | 2004-09-16 | 2005-09-16 | Fluorescent dye compounds, conjugates and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US7256292B2 (enExample) |
| EP (2) | EP1802727B1 (enExample) |
| JP (2) | JP2008513579A (enExample) |
| CN (1) | CN101258220A (enExample) |
| AU (1) | AU2005287078A1 (enExample) |
| CA (1) | CA2581174A1 (enExample) |
| SG (1) | SG155923A1 (enExample) |
| WO (1) | WO2006034036A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7570443B2 (en) | 2003-09-19 | 2009-08-04 | Applied Biosystems, Llc | Optical camera alignment |
| CA2581174A1 (en) | 2004-09-16 | 2006-03-30 | Applera Corporation | Fluorescent dye compounds, conjugates and uses thereof |
| EP2092327A2 (en) * | 2006-09-18 | 2009-08-26 | Applied Biosystems, LLC | Methods, systems and apparatus for light concentrating mechanisms |
| US20080293127A1 (en) * | 2007-05-22 | 2008-11-27 | Applera Corporation | Method to Render Pressure Sensitive Adhesive Compatible with Polymerase Chain Reaction Systems |
| US8652442B2 (en) | 2008-11-03 | 2014-02-18 | Washington University | Bioluminescence imaging of myeloperoxidase activity in vivo, methods, compositions and apparatuses therefor |
| US8614061B2 (en) * | 2008-12-01 | 2013-12-24 | Qiagen, Gmbh | Combination of fluorescent dyes for the detection of nucleic acids |
| GB201012417D0 (en) * | 2010-07-23 | 2010-09-08 | Cambridge Entpr Ltd | Capilary electrophoresis of carbohydrates |
| EP2658998B1 (en) | 2010-12-29 | 2015-04-22 | Life Technologies Corporation | Ddao compounds as fluorescent reference standards |
| TWI485145B (zh) | 2012-10-26 | 2015-05-21 | Ind Tech Res Inst | Ｐ型有機半導體材料與光電元件 |
| WO2019231617A1 (en) | 2018-05-29 | 2019-12-05 | Elitechgroup, Inc. | Carborhodamine compounds and methods of preparation thereof |
| CN115803333A (zh) | 2020-07-02 | 2023-03-14 | 生命技术公司 | 三核苷酸帽类似物、其制备和用途 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US4415732A (en) | 1981-03-27 | 1983-11-15 | University Patents, Inc. | Phosphoramidite compounds and processes |
| US4711955A (en) | 1981-04-17 | 1987-12-08 | Yale University | Modified nucleotides and methods of preparing and using same |
| US5118800A (en) | 1983-12-20 | 1992-06-02 | California Institute Of Technology | Oligonucleotides possessing a primary amino group in the terminal nucleotide |
| US4757141A (en) | 1985-08-26 | 1988-07-12 | Applied Biosystems, Incorporated | Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof |
| US4855225A (en) | 1986-02-07 | 1989-08-08 | Applied Biosystems, Inc. | Method of detecting electrophoretically separated oligonucleotides |
| US5047519A (en) | 1986-07-02 | 1991-09-10 | E. I. Du Pont De Nemours And Company | Alkynylamino-nucleotides |
| US4810636A (en) | 1986-12-09 | 1989-03-07 | Miles Inc. | Chromogenic acridinone enzyme substrates |
| ATE142202T1 (de) * | 1986-12-09 | 1996-09-15 | Bayer Ag | Acridinone als chromogene enzymsubstrate |
| US5231191A (en) | 1987-12-24 | 1993-07-27 | Applied Biosystems, Inc. | Rhodamine phosphoramidite compounds |
| DE3912046B4 (de) * | 1988-09-02 | 2004-03-25 | Carnegie Mellon University | Verfahren zum Markieren einer Komponente einer wäßrigen Flüssigkeit und lumineszenzphotostabiles Reaktionsprodukt |
| US5141813A (en) | 1989-08-28 | 1992-08-25 | Clontech Laboratories, Inc. | Multifunctional controlled pore glass reagent for solid phase oligonucleotide synthesis |
| US5393615A (en) | 1994-02-03 | 1995-02-28 | Miles Inc. | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof |
| AU698953B2 (en) | 1994-04-29 | 1998-11-12 | Applied Biosystems, Llc | System for real time detection of nucleic acid amplification products |
| US6008373A (en) | 1995-06-07 | 1999-12-28 | Carnegie Mellon University | Fluorescent labeling complexes with large stokes shift formed by coupling together cyanine and other fluorochromes capable of resonance energy transfer |
| US5728528A (en) | 1995-09-20 | 1998-03-17 | The Regents Of The University Of California | Universal spacer/energy transfer dyes |
| US5863727A (en) | 1996-05-03 | 1999-01-26 | The Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
| US5853992A (en) | 1996-10-04 | 1998-12-29 | The Regents Of The University Of California | Cyanine dyes with high-absorbance cross section as donor chromophores in energy transfer labels |
| KR100414936B1 (ko) | 1997-09-12 | 2004-01-13 | 엑시콘 에이/에스 | 이환 및 삼환 뉴클레오시드, 뉴클레오타이드 및올리고뉴클레오타이드 동족체 |
| US6583168B1 (en) * | 1997-11-25 | 2003-06-24 | Applera Corporation | Sulfonated diarylrhodamine dyes |
| GB2341189B (en) | 1998-08-31 | 2001-06-13 | Amersham Pharm Biotech Inc | Energy transfer dyes |
| ATE240310T1 (de) * | 1998-12-14 | 2003-05-15 | Vertex Pharma San Diego Llc | Optische molekularsensoren für cytochrome p-450 aktivität |
| CA2382063A1 (en) | 1999-09-17 | 2001-03-22 | Shiv Kumar | Charge-modified nucleic acid terminators |
| US6465644B1 (en) * | 2000-05-02 | 2002-10-15 | Applera Corporation | Sulfonated [8,9] benzophenoxazine dyes and the use of their labelled conjugates |
| JP2003064083A (ja) * | 2001-08-23 | 2003-03-05 | Fuji Photo Film Co Ltd | ２，３，３−トリメチル−３Ｈ−ピロロ［２，３−ｂ］ピリジン−５−スルホン酸およびその誘導体 |
| US7033762B2 (en) * | 2001-08-29 | 2006-04-25 | Amersham Biosciences Corp | Single nucleotide amplification and detection by polymerase |
| US7041812B2 (en) * | 2001-08-29 | 2006-05-09 | Amersham Biosciences Corp | Labeled nucleoside polyphosphates |
| US7052839B2 (en) * | 2001-08-29 | 2006-05-30 | Amersham Biosciences Corp | Terminal-phosphate-labeled nucleotides and methods of use |
| US7223541B2 (en) * | 2001-08-29 | 2007-05-29 | Ge Healthcare Bio-Sciences Corp. | Terminal-phosphate-labeled nucleotides and methods of use |
| WO2003020603A1 (en) * | 2001-09-06 | 2003-03-13 | Robert John Galway | Collapsible packing boxes |
| WO2003025192A2 (en) * | 2001-09-19 | 2003-03-27 | Pe Corporation (Ny) | Membrane transportable fluorescent substrates |
| CA2433473A1 (en) | 2002-07-23 | 2004-01-23 | F. Hoffmann-La Roche Ag | Fluorescent hybridization probes with reduced background |
| WO2004020603A2 (en) * | 2002-08-29 | 2004-03-11 | Amersham Biosciences Corp | Analyte detection |
| CA2496462C (en) * | 2002-08-29 | 2014-01-28 | Amersham Biosciences Corp | Allele specific primer extension |
| US6855503B2 (en) | 2002-12-20 | 2005-02-15 | Amersham Biosciences Corp | Heterocyclic FRETdye cassettes for labeling biological molecules and their use in DNA sequencing |
| US7125671B2 (en) * | 2003-02-05 | 2006-10-24 | Ge Healthcare Bio-Sciences Corp. | Nucleic acid amplification with terminal-phosphate labeled nucleotides |
| CA2581174A1 (en) | 2004-09-16 | 2006-03-30 | Applera Corporation | Fluorescent dye compounds, conjugates and uses thereof |
| US20100227327A1 (en) | 2008-08-08 | 2010-09-09 | Xiaoliang Sunney Xie | Methods and compositions for continuous single-molecule nucleic acid sequencing by synthesis with fluorogenic nucleotides |
| WO2011031497A2 (en) | 2009-08-25 | 2011-03-17 | Life Technologies Corporation | Quantitative fluorescent protein standards |
| EP2658998B1 (en) | 2010-12-29 | 2015-04-22 | Life Technologies Corporation | Ddao compounds as fluorescent reference standards |
-
2005
- 2005-09-16 CA CA002581174A patent/CA2581174A1/en not_active Abandoned
- 2005-09-16 SG SG200906144-1A patent/SG155923A1/en unknown
- 2005-09-16 AU AU2005287078A patent/AU2005287078A1/en not_active Abandoned
- 2005-09-16 WO PCT/US2005/033174 patent/WO2006034036A1/en not_active Ceased
- 2005-09-16 EP EP05801162.8A patent/EP1802727B1/en not_active Expired - Lifetime
- 2005-09-16 US US11/229,012 patent/US7256292B2/en not_active Expired - Lifetime
- 2005-09-16 JP JP2007532501A patent/JP2008513579A/ja active Pending
- 2005-09-16 CN CNA2005800310384A patent/CN101258220A/zh active Pending
- 2005-09-16 EP EP11004494.8A patent/EP2371927B1/en not_active Expired - Lifetime
-
2007
- 2007-12-17 US US11/838,793 patent/US7985602B2/en active Active
-
2008
- 2008-09-11 JP JP2008233982A patent/JP2009041027A/ja active Pending
-
2011
- 2011-06-21 US US13/165,575 patent/US8729267B2/en active Active
-
2014
- 2014-03-28 US US14/229,663 patent/US9745336B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2371927B1 (en) | 2020-03-11 |
| EP1802727A1 (en) | 2007-07-04 |
| US20090093062A1 (en) | 2009-04-09 |
| EP1802727B1 (en) | 2018-04-04 |
| CN101258220A (zh) | 2008-09-03 |
| AU2005287078A1 (en) | 2006-03-30 |
| US7256292B2 (en) | 2007-08-14 |
| US20140303003A1 (en) | 2014-10-09 |
| JP2008513579A (ja) | 2008-05-01 |
| CA2581174A1 (en) | 2006-03-30 |
| US7985602B2 (en) | 2011-07-26 |
| WO2006034036A1 (en) | 2006-03-30 |
| US20110250699A1 (en) | 2011-10-13 |
| US9745336B2 (en) | 2017-08-29 |
| US8729267B2 (en) | 2014-05-20 |
| US20060167257A1 (en) | 2006-07-27 |
| JP2009041027A (ja) | 2009-02-26 |
| EP2371927A1 (en) | 2011-10-05 |
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