SG148192A1 - Azabenzimidazole derivatives, their manufacture and use as anti-cancer agents - Google Patents

Azabenzimidazole derivatives, their manufacture and use as anti-cancer agents

Info

Publication number
SG148192A1
SG148192A1 SG200808633-2A SG2008086332A SG148192A1 SG 148192 A1 SG148192 A1 SG 148192A1 SG 2008086332 A SG2008086332 A SG 2008086332A SG 148192 A1 SG148192 A1 SG 148192A1
Authority
SG
Singapore
Prior art keywords
manufacture
cancer agents
azabenzimidazole derivatives
azabenzimidazole
derivatives
Prior art date
Application number
SG200808633-2A
Other languages
English (en)
Inventor
Richard Engh
Hubert Hertenberger
Konrad Honold
Birgit Masjost
Petra Rueger
Wolfgang Schaefer
Stefan Scheiblich
Manfred Schwaiger
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SG148192A1 publication Critical patent/SG148192A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG200808633-2A 2005-07-29 2006-07-28 Azabenzimidazole derivatives, their manufacture and use as anti-cancer agents SG148192A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05016607 2005-07-29

Publications (1)

Publication Number Publication Date
SG148192A1 true SG148192A1 (en) 2008-12-31

Family

ID=34979704

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200808633-2A SG148192A1 (en) 2005-07-29 2006-07-28 Azabenzimidazole derivatives, their manufacture and use as anti-cancer agents

Country Status (9)

Country Link
US (1) US20090227578A1 (zh)
EP (1) EP1919910B1 (zh)
JP (1) JP2009502843A (zh)
CN (1) CN101208338B (zh)
AT (1) ATE499372T1 (zh)
CA (1) CA2614156A1 (zh)
DE (1) DE602006020295D1 (zh)
SG (1) SG148192A1 (zh)
WO (1) WO2007017143A1 (zh)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010502660A (ja) * 2006-09-06 2010-01-28 エフ．ホフマン−ラ ロシュ アーゲー プロテインキナーゼインヒビターとしてのヘテロアリール誘導体
WO2008144253A1 (en) * 2007-05-14 2008-11-27 Irm Llc Protein kinase inhibitors and methods for using thereof
ES2569660T3 (es) 2007-06-08 2016-05-12 Mannkind Corporation Inhibidores de la IRE-1alfa
US20110003809A1 (en) * 2008-02-29 2011-01-06 Array Biopharma Inc. Imidazo [4,5-b] pyridine derivatives used as raf inhibitors
AU2009222144A1 (en) 2008-02-29 2009-09-11 Array Biopharma Inc. Pyrazole [3, 4-b] pyridine Raf inhibitors
PE20091561A1 (es) 2008-02-29 2009-10-30 Array Biopharma Inc Compuestos inhibidores de raf y metodos para su uso
UY34305A (es) * 2011-09-01 2013-04-30 Novartis Ag Derivados de heterociclos bicíclicos para el tratamiento de la hipertensión arterial pulmonar
FR3000492B1 (fr) 2012-12-28 2015-09-11 Oribase Pharma Nouveaux derives azaindole en tant qu'inhibiteurs multikinases
FR3000494B1 (fr) 2012-12-28 2015-08-21 Oribase Pharma Nouveaux derives d'azaindoles en tant qu'inhibiteurs de proteines kinases
FR3000493A1 (fr) 2012-12-28 2014-07-04 Oribase Pharma Nouveaux inhibiteurs de proteines kinases
WO2014151630A2 (en) 2013-03-15 2014-09-25 Irm Llc Compounds and compositions for the treatment of parasitic diseases
US9186361B2 (en) 2013-03-15 2015-11-17 Novartis Ag Compounds and compositions for the treatment of parasitic diseases
US9296754B2 (en) 2013-03-15 2016-03-29 Novartis Ag Compounds and compositions for the treatment of parasitic diseases
HUE040254T2 (hu) 2013-12-19 2019-02-28 Novartis Ag Protozoa proteaszóma inhibitor [1,2,4]triazolo[1,5-a]pirimidinszármazékok paraziták által okozott betegségek, például leishmaniasis kezelésére
JP7301862B2 (ja) * 2018-02-23 2023-07-03 フラウンホーファー－ゲゼルシャフト ツル フェルデルング デル アンゲヴァンテン フォルシュング エー ファウ 歯周病及び関連疾患の治療に用いる細菌性グルタミニルシクラーゼの新規阻害剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002334217B2 (en) * 2001-10-26 2008-07-03 Aventis Pharmaceuticals Inc. Benzimidazoles and analogues and their use as protein kinases inhibitors

Also Published As

Publication number Publication date
CA2614156A1 (en) 2007-02-15
WO2007017143A1 (en) 2007-02-15
EP1919910A1 (en) 2008-05-14
EP1919910B1 (en) 2011-02-23
DE602006020295D1 (de) 2011-04-07
CN101208338B (zh) 2010-12-29
US20090227578A1 (en) 2009-09-10
ATE499372T1 (de) 2011-03-15
JP2009502843A (ja) 2009-01-29
CN101208338A (zh) 2008-06-25

Similar Documents

Publication Publication Date Title
SG148192A1 (en) Azabenzimidazole derivatives, their manufacture and use as anti-cancer agents
EP2223921B8 (en) 2-Thiophen-2-yl-oxazole, 2-Thiophen-2-yl-thiazole and 2-Thiophen-2-yl-1H-imidazole derivatives as antiviral agents
IL192009A0 (en) Quinazoline derivatives, process for their preparation and their use as anti-cancer agents
IL185381A0 (en) Cis-2,4,5-triaryl-imidazolines and their use as anti-cancer medicaments
IL192948A0 (en) Novel pyridine derivatives
IL185484A0 (en) Aminopyrazole derivatives, their manufacture and use as pharmaceutical agents
MX2010004576A (es) Derivados de pirimidina novedosos.
IL184901A0 (en) 2,4-diamino-pyridopyrimidine derivatives and their use as mtor inhibitors
MY153921A (en) Aminopyrazole derivatives
MX2009004883A (es) Piridil sulfoximinas multi-substituidas y su uso como insecticidas.
SG149831A1 (en) Benzimidazole derivatives
EP1961753A4 (en) DERIVATIVES OF PIRAZOLOPYRIMIDINONE, THEIR PREPARATION AND USE
IL184314A0 (en) Substituted 4-phenyltetrahydroisoquinolines, methods for producing them, their use as drug, and drug containing them
MX2010009927A (es) Derivados de espiroindolinona.
IL193155A0 (en) Tetrahydronaphthaline derivatives, methods for the production and use thereof as anti-inflammatory agents
ZA200706672B (en) 2,4-Diamino-pyridopyrimidine derivatives and their use as mTOR inhibitors
ZA201000581B (en) 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-6-carboxamide and 2,3,4,5-tetrahydropyrrolo[1,2-a][1,4]-diazepine-7-carboxamide derivatives,preparation and therapeutic use thereof
IL190334A0 (en) Pyridylsulfonamide derivatives, their manufacture and use as antineoplastic agents
IL186851A0 (en) Styrylsulfonamides, their manufacture and use as pharmaceutical agents
IL188185A0 (en) Phenylpyridine derivatives, their manufacture and use as pharmaceutical agents
IL187419A0 (en) Heteroarylethenyl derivatives, their manufacture and use as pharmaceutical agents
CA118758S (en) Table support structure
AU302485S (en) Side table
AU300903S (en) Dining set
AU305696S (en) Bookcase