SG11202113242QA - Isolation of fetal cells using facs - Google Patents

Isolation of fetal cells using facs

Info

Publication number
SG11202113242QA
SG11202113242QA SG11202113242QA SG11202113242QA SG11202113242QA SG 11202113242Q A SG11202113242Q A SG 11202113242QA SG 11202113242Q A SG11202113242Q A SG 11202113242QA SG 11202113242Q A SG11202113242Q A SG 11202113242QA SG 11202113242Q A SG11202113242Q A SG 11202113242QA
Authority
SG
Singapore
Prior art keywords
facs
isolation
fetal cells
fetal
cells
Prior art date
Application number
SG11202113242QA
Other languages
English (en)
Inventor
Bolette Nicolaisen
David Kølvraa
Inga Christensen
Katarina Ravn
Line Jeppesen
Lotte Hatt
Palle Jensen
Ripudaman Singh
Original Assignee
Arcedi Biotech Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arcedi Biotech Aps filed Critical Arcedi Biotech Aps
Publication of SG11202113242QA publication Critical patent/SG11202113242QA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/689Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/36Gynecology or obstetrics
    • G01N2800/368Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SG11202113242QA 2019-06-07 2020-06-08 Isolation of fetal cells using facs SG11202113242QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19179087 2019-06-07
PCT/EP2020/065832 WO2020245459A1 (en) 2019-06-07 2020-06-08 Isolation of fetal cells using facs

Publications (1)

Publication Number Publication Date
SG11202113242QA true SG11202113242QA (en) 2021-12-30

Family

ID=66793879

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202113242QA SG11202113242QA (en) 2019-06-07 2020-06-08 Isolation of fetal cells using facs

Country Status (17)

Country Link
US (2) US11573229B2 (es)
EP (2) EP4242652A3 (es)
JP (1) JP2022536121A (es)
KR (1) KR20220047929A (es)
CN (1) CN114041053A (es)
AU (1) AU2020289708B2 (es)
BR (1) BR112021024474A2 (es)
CA (1) CA3142663A1 (es)
EA (1) EA202193200A1 (es)
ES (1) ES2955791T3 (es)
IL (2) IL288621B2 (es)
MX (1) MX2021015044A (es)
PL (1) PL3980773T3 (es)
SG (1) SG11202113242QA (es)
UA (1) UA128273C2 (es)
WO (1) WO2020245459A1 (es)
ZA (1) ZA202110215B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4242652A3 (en) 2019-06-07 2023-12-06 Arcedi Biotech ApS Isolation of fetal cells using facs
CN113087793B (zh) * 2021-05-12 2022-04-12 福州迈新生物技术开发有限公司 抗ck14蛋白单克隆抗体及其细胞株、制备方法和应用
CN112980779B (zh) * 2021-05-20 2021-08-24 广州凯普医药科技有限公司 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法
EP4445135A1 (en) * 2021-12-06 2024-10-16 Arcedi Biotech ApS Isolation and diagnostics of fetal cells

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5641628A (en) 1989-11-13 1997-06-24 Children's Medical Center Corporation Non-invasive method for isolation and detection of fetal DNA
US5629147A (en) 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
JPH08511205A (ja) 1993-04-02 1996-11-26 ジェオ リサーチ エス.アー.エール.エル. 低温流体の噴射による切断設備と方法
WO1995003431A1 (en) 1993-07-19 1995-02-02 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
US5714325A (en) 1993-09-24 1998-02-03 New England Medical Center Hospitals Prenatal diagnosis by isolation of fetal granulocytes from maternal blood
US5648222A (en) 1994-07-27 1997-07-15 The Trustees Of Columbia University In The City Of New York Method for preserving cells, and uses of said method
GB9603249D0 (en) 1996-02-16 1996-04-17 Univ Nottingham Foetal cell analysis
GB0009179D0 (en) 2000-04-13 2000-05-31 Imp College Innovations Ltd Non-invasive prenatal diagnosis
EP1302533A4 (en) 2000-05-16 2004-11-17 Kyowa Hakko Kogyo Kk NEW METHOD FOR INDUCING DIFFERENTIATION OF EMBRYONIC STEM CELLS IN EECTODERMAL CELLS AND THEIR USE
AU2002306768A1 (en) 2001-03-20 2002-10-03 Ortho-Clinical Diagnostics, Inc. Expression profiles and methods of use
US20030036100A1 (en) 2001-04-10 2003-02-20 Imperial College Innovations Ltd. Simultaneous determination of phenotype and genotype
FR2824144B1 (fr) 2001-04-30 2004-09-17 Metagenex S A R L Methode de diagnostic prenatal sur cellule foetale isolee du sang maternel
EP1572087B1 (en) 2002-03-08 2008-05-14 PDL BioPharma, Inc. Antibodies against cancer antigen tmeff2 and uses thereof
US20050181429A1 (en) 2003-04-03 2005-08-18 Monaliza Medical Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
US20040197832A1 (en) 2003-04-03 2004-10-07 Mor Research Applications Ltd. Non-invasive prenatal genetic diagnosis using transcervical cells
TWI367260B (en) 2005-03-18 2012-07-01 Univ Hong Kong Chinese Method for detecting the presence of a fetus with trisomy 21 in a pregnant woman and kit thereof
WO2006119569A1 (en) 2005-05-11 2006-11-16 Genetic Technologies Limtied Methods of enriching fetal cells
DE602006017878D1 (de) 2005-12-08 2010-12-09 Fcmb Aps Nachweis fötaler zellen aus mütterlichem blut
GB0616045D0 (en) 2006-08-11 2006-09-20 Univ Bristol Blood cell separation
ES2564312T3 (es) 2007-05-01 2016-03-21 Tel Hashomer Medical Research Infrastructure And Services Ltd. Métodos y kits para detectar células fetales en la sangre materna
EP2250497B1 (en) 2008-02-18 2014-09-10 Genetic Technologies Limited Cell processing and/or enrichment methods
PT2385992E (pt) 2009-01-07 2015-04-16 Arcedi Biotech Aps Enriquecimento e identificação de células fetais em sangue materno e ligandos para esse uso
RU2011147219A (ru) 2009-04-22 2013-05-27 Клиникал Джиномикс Пти. Лтд. Способ и устройство для изолирования искомой биочастицы из биологического образца
HUE034937T2 (en) 2010-11-09 2018-03-28 Arcedi Biotech Aps Enrichment and detection of fetal cells from maternal blood and ligands for this purpose
EP4008270A1 (en) 2012-06-22 2022-06-08 Preprogen LLC Method for obtaining fetal cells and fetal cellular components
EP3489691A1 (en) 2014-05-15 2019-05-29 Kellbenx Inc. Preparation of fetal nucleated red blood cells (nrbcs) for diagnostic testing
EP4242652A3 (en) 2019-06-07 2023-12-06 Arcedi Biotech ApS Isolation of fetal cells using facs

Also Published As

Publication number Publication date
MX2021015044A (es) 2022-04-06
IL288621B2 (en) 2024-05-01
CN114041053A (zh) 2022-02-11
IL288621B1 (en) 2024-01-01
KR20220047929A (ko) 2022-04-19
CA3142663A1 (en) 2020-12-10
UA128273C2 (uk) 2024-05-22
EA202193200A1 (ru) 2022-03-17
ES2955791T3 (es) 2023-12-07
WO2020245459A1 (en) 2020-12-10
EP3980773B1 (en) 2023-07-12
AU2020289708A1 (en) 2022-01-20
US20210199664A1 (en) 2021-07-01
AU2020289708B2 (en) 2024-07-25
PL3980773T3 (pl) 2023-11-27
EP3980773A1 (en) 2022-04-13
JP2022536121A (ja) 2022-08-12
BR112021024474A2 (pt) 2022-01-18
EP4242652A3 (en) 2023-12-06
IL288621A (en) 2022-02-01
US11573229B2 (en) 2023-02-07
US20230130312A1 (en) 2023-04-27
ZA202110215B (en) 2023-06-28
IL308999A (en) 2024-01-01
EP4242652A2 (en) 2023-09-13
EP3980773C0 (en) 2023-07-12

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