SG11202111378SA - Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives - Google Patents

Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives

Info

Publication number
SG11202111378SA
SG11202111378SA SG11202111378SA SG11202111378SA SG11202111378SA SG 11202111378S A SG11202111378S A SG 11202111378SA SG 11202111378S A SG11202111378S A SG 11202111378SA SG 11202111378S A SG11202111378S A SG 11202111378SA SG 11202111378S A SG11202111378S A SG 11202111378SA
Authority
SG
Singapore
Prior art keywords
ethylamino
phenyl
substituted
production
alkaneamide derivatives
Prior art date
Application number
SG11202111378SA
Other languages
English (en)
Inventor
Wolfgang Skranc
Michael Wolberg
Matthias Riepl
Christoph Imboden
Erwin Waldvogel
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Publication of SG11202111378SA publication Critical patent/SG11202111378SA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/60—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C253/00—Preparation of carboxylic acid nitriles
    • C07C253/08—Preparation of carboxylic acid nitriles by addition of hydrogen cyanide or salts thereof to unsaturated compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/36—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by hydroxy groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SG11202111378SA 2019-04-17 2020-04-08 Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives SG11202111378SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19169714.3A EP3725768A1 (de) 2019-04-17 2019-04-17 Verfahren zur herstellung von substituierten 2-[2-(phenyl)ethylamino]alkanamid-derivaten
PCT/EP2020/060037 WO2020212227A1 (en) 2019-04-17 2020-04-08 Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives

Publications (1)

Publication Number Publication Date
SG11202111378SA true SG11202111378SA (en) 2021-11-29

Family

ID=66217869

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202111378SA SG11202111378SA (en) 2019-04-17 2020-04-08 Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives

Country Status (14)

Country Link
US (1) US20220177417A1 (de)
EP (2) EP3725768A1 (de)
JP (1) JP2022529916A (de)
KR (1) KR20210154206A (de)
CN (1) CN113784944A (de)
AR (1) AR118674A1 (de)
AU (1) AU2020259726A1 (de)
BR (1) BR112021020599A2 (de)
CA (1) CA3136845A1 (de)
IL (1) IL287228A (de)
MA (1) MA55710A (de)
MX (1) MX2021012713A (de)
SG (1) SG11202111378SA (de)
WO (1) WO2020212227A1 (de)

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0127559D0 (en) * 2001-11-16 2002-01-09 Syngenta Participations Ag Organic compounds
PT1572214E (pt) * 2002-12-10 2010-05-06 Pfizer Morfolina derivados para utilização como agonistas da dopamina no tratamento da disfunção sexual i.a.
JP4795965B2 (ja) * 2003-11-12 2011-10-19 エルジー・ライフ・サイエンシーズ・リミテッド メラノコルチン受容体のアゴニスト
KR101380137B1 (ko) * 2005-12-22 2014-04-11 뉴론 파마슈티칼즈 에스. 피. 에이. 칼슘 및/또는 나트륨 채널 조절제로서 2-페닐에틸아미노유도체
US8183413B2 (en) * 2006-01-20 2012-05-22 Kaneka Corporation Process for production of β-amino-α-hydroxy carboxamide derivative
NO2155663T3 (de) 2007-06-15 2018-04-28
KR101709498B1 (ko) * 2007-12-11 2017-02-23 뉴론 파마슈티칼즈 에스. 피. 에이. 고순도의 ２­［４­（３­ 또는 ２­플루오로벤질옥시）벤질아미노］프로판아미드의 제조방법
PT2723710T (pt) 2011-06-27 2016-11-14 Newron Pharm Spa Derivados fluorados de arilalquilaminocarboxamida
CN105518001A (zh) * 2013-07-09 2016-04-20 拜耳制药股份公司 Bet蛋白抑制性的改性的二氢喹喔啉酮类化合物和二氢吡啶并吡嗪酮类化合物
CN105801437A (zh) * 2016-03-31 2016-07-27 常州大学 一种(甲基氨基)(苯基)甲醇的合成方法
CN114249668A (zh) * 2020-09-25 2022-03-29 鲁南制药集团股份有限公司 一种唑吡坦中间体n,n-二甲基-2-氧乙酰胺的制备方法

Also Published As

Publication number Publication date
AU2020259726A1 (en) 2021-12-09
CN113784944A (zh) 2021-12-10
IL287228A (en) 2021-12-01
US20220177417A1 (en) 2022-06-09
BR112021020599A2 (pt) 2021-12-07
MA55710A (fr) 2022-02-23
EP3956295A1 (de) 2022-02-23
MX2021012713A (es) 2021-11-12
TW202104164A (zh) 2021-02-01
WO2020212227A1 (en) 2020-10-22
KR20210154206A (ko) 2021-12-20
EP3725768A1 (de) 2020-10-21
CA3136845A1 (en) 2020-10-22
AR118674A1 (es) 2021-10-20
JP2022529916A (ja) 2022-06-27

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