SG11202111376PA - Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives - Google Patents

Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives

Info

Publication number
SG11202111376PA
SG11202111376PA SG11202111376PA SG11202111376PA SG11202111376PA SG 11202111376P A SG11202111376P A SG 11202111376PA SG 11202111376P A SG11202111376P A SG 11202111376PA SG 11202111376P A SG11202111376P A SG 11202111376PA SG 11202111376P A SG11202111376P A SG 11202111376PA
Authority
SG
Singapore
Prior art keywords
ethylamino
phenyl
substituted
production
alkaneamide derivatives
Prior art date
Application number
SG11202111376PA
Other languages
English (en)
Inventor
William Leong
Dongxiao Lan
Weifang Zhang
Xiang Fang
Sizhong Wu
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Publication of SG11202111376PA publication Critical patent/SG11202111376PA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/14Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001Acyclic or carbocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • C07C41/14Preparation of ethers by exchange of organic parts on the ether-oxygen for other organic parts, e.g. by trans-etherification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01Preparation of ethers
    • C07C41/18Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/215Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/20Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11202111376PA 2019-04-17 2020-04-14 Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives SG11202111376PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19169715.0A EP3725769A1 (en) 2019-04-17 2019-04-17 Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives
PCT/EP2020/060470 WO2020212352A1 (en) 2019-04-17 2020-04-14 Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives

Publications (1)

Publication Number Publication Date
SG11202111376PA true SG11202111376PA (en) 2021-11-29

Family

ID=66217870

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202111376PA SG11202111376PA (en) 2019-04-17 2020-04-14 Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives

Country Status (15)

Country Link
US (1) US20220185766A1 (zh)
EP (2) EP3725769A1 (zh)
JP (1) JP2022529000A (zh)
KR (1) KR20210154213A (zh)
CN (1) CN113710645A (zh)
AR (1) AR118675A1 (zh)
AU (1) AU2020259813A1 (zh)
BR (1) BR112021020595A2 (zh)
CA (1) CA3136846A1 (zh)
IL (1) IL287230A (zh)
MA (1) MA55714A (zh)
MX (1) MX2021012711A (zh)
SG (1) SG11202111376PA (zh)
TW (1) TW202104170A (zh)
WO (1) WO2020212352A1 (zh)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020055631A1 (en) * 2000-09-20 2002-05-09 Augeri David J. N-acylsulfonamide apoptosis promoters
WO2008151702A1 (en) 2007-06-15 2008-12-18 Newron Pharmaceuticals S.P.A. Substituted 2- [2- (phenyl) ethylamino] alkaneamide derivatives and their use as sodium and/or calcium channel modulators
MX2011004324A (es) * 2008-11-07 2011-09-21 Ucb Pharma Gmbh Proceso novedoso para la preparacion de derivados de aminoacidos.
WO2010144891A1 (en) * 2009-06-13 2010-12-16 President And Fellows Of Harvard College Compositions and methods for imaging tissues, organs and tumors
PT2723710T (pt) 2011-06-27 2016-11-14 Newron Pharm Spa Derivados fluorados de arilalquilaminocarboxamida
CN103930400B (zh) * 2011-11-11 2016-04-20 霍夫曼-拉罗奇有限公司 制备1-酰基-4-苯基磺酰基脯氨酰胺衍生物的方法及中间体

Also Published As

Publication number Publication date
BR112021020595A2 (pt) 2021-12-07
WO2020212352A1 (en) 2020-10-22
AU2020259813A1 (en) 2021-12-02
AR118675A1 (es) 2021-10-20
CN113710645A (zh) 2021-11-26
MX2021012711A (es) 2021-11-12
KR20210154213A (ko) 2021-12-20
IL287230A (en) 2021-12-01
EP3725769A1 (en) 2020-10-21
TW202104170A (zh) 2021-02-01
CA3136846A1 (en) 2020-10-22
JP2022529000A (ja) 2022-06-16
US20220185766A1 (en) 2022-06-16
MA55714A (fr) 2022-02-23
EP3956296A1 (en) 2022-02-23

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