SG11202111376PA - Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives - Google Patents

Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives

Info

Publication number
SG11202111376PA
SG11202111376PA SG11202111376PA SG11202111376PA SG11202111376PA SG 11202111376P A SG11202111376P A SG 11202111376PA SG 11202111376P A SG11202111376P A SG 11202111376PA SG 11202111376P A SG11202111376P A SG 11202111376PA SG 11202111376P A SG11202111376P A SG 11202111376PA
Authority
SG
Singapore
Prior art keywords
ethylamino
phenyl
substituted
production
alkaneamide derivatives
Prior art date
Application number
SG11202111376PA
Inventor
William Leong
Dongxiao Lan
Weifang Zhang
Xiang Fang
Sizhong Wu
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Publication of SG11202111376PA publication Critical patent/SG11202111376PA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001—Acyclic or carbocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/14—Preparation of ethers by exchange of organic parts on the ether-oxygen for other organic parts, e.g. by trans-etherification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/215—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring having unsaturation outside the six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/64—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05—Isotopically modified compounds, e.g. labelled

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG11202111376PA 2019-04-17 2020-04-14 Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives SG11202111376PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19169715.0A EP3725769A1 (en) 2019-04-17 2019-04-17 Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives
PCT/EP2020/060470 WO2020212352A1 (en) 2019-04-17 2020-04-14 Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives

Publications (1)

Publication Number Publication Date
SG11202111376PA true SG11202111376PA (en) 2021-11-29

Family

ID=66217870

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202111376PA SG11202111376PA (en) 2019-04-17 2020-04-14 Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives

Country Status (15)

Country Link
US (1) US20220185766A1 (en)
EP (2) EP3725769A1 (en)
JP (1) JP2022529000A (en)
KR (1) KR20210154213A (en)
CN (1) CN113710645A (en)
AR (1) AR118675A1 (en)
AU (1) AU2020259813A1 (en)
BR (1) BR112021020595A2 (en)
CA (1) CA3136846A1 (en)
IL (1) IL287230A (en)
MA (1) MA55714A (en)
MX (1) MX2021012711A (en)
SG (1) SG11202111376PA (en)
TW (1) TW202104170A (en)
WO (1) WO2020212352A1 (en)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020055631A1 (en) * 2000-09-20 2002-05-09 Augeri David J. N-acylsulfonamide apoptosis promoters
PL2155663T3 (en) 2007-06-15 2018-06-29 Newron Pharmaceuticals S.P.A. Substituted 2-[2-(phenyl)ethylamino]alkaneamide derivatives and their use as sodium and/or calcium channel modulators
KR101755548B1 (en) * 2008-11-07 2017-07-07 유씨비 파르마 게엠베하 Novel process for the preparation of amino acid derivatives
WO2010144891A1 (en) * 2009-06-13 2010-12-16 President And Fellows Of Harvard College Compositions and methods for imaging tissues, organs and tumors
JP6116555B2 (en) 2011-06-27 2017-04-19 ニユーロン・フアーマシユーテイカルズ・エツセ・ピー・アー Fluorinated arylalkylaminocarboxamide derivatives
AU2012334123B2 (en) * 2011-11-11 2016-12-15 F. Hoffmann-La Roche Ag Process for the preparation of 1-acyl-4-phenylsulfonylprolinamide derivatives and new intermediates

Also Published As

Publication number Publication date
WO2020212352A1 (en) 2020-10-22
MA55714A (en) 2022-02-23
US20220185766A1 (en) 2022-06-16
BR112021020595A2 (en) 2021-12-07
AR118675A1 (en) 2021-10-20
TW202104170A (en) 2021-02-01
AU2020259813A1 (en) 2021-12-02
CN113710645A (en) 2021-11-26
EP3725769A1 (en) 2020-10-21
JP2022529000A (en) 2022-06-16
EP3956296A1 (en) 2022-02-23
MX2021012711A (en) 2021-11-12
CA3136846A1 (en) 2020-10-22
IL287230A (en) 2021-12-01
KR20210154213A (en) 2021-12-20

Similar Documents

Publication Publication Date Title
SG11202005382YA (en) Process for the preparation of microcapsules
SG11202108238VA (en) Process for the preparation of methionine
MA50169A (en) PROCESS FOR THE PRODUCTION OF AN ELECTROCATALYZER
IL290181A (en) Process for the preparation of fluensulfone
PL3696156T3 (en) New process for the manufacture of fluoroaryl compounds and derivatives
IL282703A (en) Novel compounds useful for treating cardiovascular diseases
IL287230A (en) Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives
IL287228A (en) Process for the production of substituted 2-[2-(phenyl) ethylamino]alkaneamide derivatives
IL289904A (en) Process for the preparation of biphenylamines
IL276483B1 (en) Continuous process for the preparation of trazodone
HUE044642T2 (en) Process for the production of 2-[4-(cyclopropanecarbonyl)phenyl]-2-methyl-propanenitrile
IL281720A (en) Hmgb1 protein derivatives for the removal of biofilms
DK3864016T3 (en) PROCESS FOR THE PRODUCTION OF SUBSTITUTED IMIDAZOLE DERIVATIVES
GB2594228B (en) Mould for the manufacture of ceramic packing members
DK3864015T3 (en) PROCEDURE FOR THE PRODUCTION OF IMIDAZOLE DERIVATIVES
PT3759082T (en) Process for the synthesis of 6-chloromethyluracil
DK3790637T3 (en) Process for the production of dry powders
PH12017500124A1 (en) Azole benzene derivative and crystalline form thereof
IL278817A (en) Process for producing substituted 4-aminoindane derivatives from 2-(hydroxyalkyl)-anilines
PT3980434T (en) Process for the preparation of the polymorph f of sodium neridronate
SG10201906863XA (en) Process for the purification of acrolein
IL290214A (en) Continuous process for preparing the crystalline form ii of sotagliflozin
EP4081509A4 (en) Novel compounds suitable for the treatment of dyslipidemia
IL259176A (en) Process for the production of titanium salts
HUP1900118A1 (en) Novel process for the production of propylene