SG11202109213RA - Process for preparing 6- (1-acryloylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamide - Google Patents
Process for preparing 6- (1-acryloylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamideInfo
- Publication number
- SG11202109213RA SG11202109213RA SG11202109213RA SG11202109213RA SG11202109213RA SG 11202109213R A SG11202109213R A SG 11202109213RA SG 11202109213R A SG11202109213R A SG 11202109213RA SG 11202109213R A SG11202109213R A SG 11202109213RA SG 11202109213R A SG11202109213R A SG 11202109213RA
- Authority
- SG
- Singapore
- Prior art keywords
- acryloylpiperidin
- phenoxyphenyl
- nicotinamide
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Health & Medical Sciences (AREA)
- Hydrogenated Pyridines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Medicinal Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962810305P | 2019-02-25 | 2019-02-25 | |
| PCT/CN2020/076387 WO2020173407A1 (en) | 2019-02-25 | 2020-02-24 | Process for preparing 6- (1-acryloylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202109213RA true SG11202109213RA (en) | 2021-09-29 |
Family
ID=72238782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202109213RA SG11202109213RA (en) | 2019-02-25 | 2020-02-24 | Process for preparing 6- (1-acryloylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamide |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20210380555A1 (es) |
| EP (1) | EP3931182A4 (es) |
| JP (1) | JP2022521763A (es) |
| KR (1) | KR20210131374A (es) |
| CN (1) | CN113454066B (es) |
| AU (1) | AU2020229919A1 (es) |
| BR (1) | BR112021016787A2 (es) |
| CA (1) | CA3131302A1 (es) |
| MX (1) | MX2021010199A (es) |
| SG (1) | SG11202109213RA (es) |
| TW (1) | TWI830876B (es) |
| WO (1) | WO2020173407A1 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115894440A (zh) * | 2022-10-27 | 2023-04-04 | 都创(重庆)医药科技有限公司 | 奥布替尼化合物的晶型及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2648923A1 (en) * | 2006-04-11 | 2007-10-18 | Vertex Pharmaceuticals Incorporated | Thiazoles, imidazoles, and pyrazoles useful as inhibitors of protein kinases |
| JP6615752B2 (ja) * | 2013-09-30 | 2019-12-04 | グアンジョウ・イノケア・ファーマ・テク・カンパニー・リミテッド | Ｂｔｋの置換ニコチンイミド阻害剤およびそれらの調製、ならびにがん、炎症および自己免疫疾患の治療における使用 |
| CN107226805A (zh) * | 2016-03-24 | 2017-10-03 | 北京天诚医药科技有限公司 | 芳香族酰胺类衍生物、其制备方法及其在医药上的应用 |
| WO2020093896A1 (en) * | 2018-11-06 | 2020-05-14 | Beijing Innocare Pharma Tech Co., Ltd. | Amorphous solid dispersion comprising 6- (1-acryloylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamide |
-
2020
- 2020-02-24 AU AU2020229919A patent/AU2020229919A1/en active Pending
- 2020-02-24 JP JP2021549695A patent/JP2022521763A/ja active Pending
- 2020-02-24 EP EP20762224.2A patent/EP3931182A4/en active Pending
- 2020-02-24 SG SG11202109213RA patent/SG11202109213RA/en unknown
- 2020-02-24 CA CA3131302A patent/CA3131302A1/en active Pending
- 2020-02-24 WO PCT/CN2020/076387 patent/WO2020173407A1/en unknown
- 2020-02-24 KR KR1020217029894A patent/KR20210131374A/ko active Search and Examination
- 2020-02-24 BR BR112021016787A patent/BR112021016787A2/pt unknown
- 2020-02-24 CN CN202080015876.7A patent/CN113454066B/zh active Active
- 2020-02-24 MX MX2021010199A patent/MX2021010199A/es unknown
- 2020-02-25 TW TW109106065A patent/TWI830876B/zh active
-
2021
- 2021-08-20 US US17/407,340 patent/US20210380555A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020173407A1 (en) | 2020-09-03 |
| CN113454066B (zh) | 2024-02-09 |
| TW202031642A (zh) | 2020-09-01 |
| CN113454066A (zh) | 2021-09-28 |
| MX2021010199A (es) | 2021-09-21 |
| JP2022521763A (ja) | 2022-04-12 |
| EP3931182A1 (en) | 2022-01-05 |
| KR20210131374A (ko) | 2021-11-02 |
| CA3131302A1 (en) | 2020-09-03 |
| EP3931182A4 (en) | 2023-01-25 |
| US20210380555A1 (en) | 2021-12-09 |
| AU2020229919A1 (en) | 2021-10-14 |
| BR112021016787A2 (pt) | 2021-11-16 |
| TWI830876B (zh) | 2024-02-01 |
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