SG11202108922WA - Piezo type mechanosensitive ion channel component 1 (piezo1) variants and uses thereof - Google Patents
Piezo type mechanosensitive ion channel component 1 (piezo1) variants and uses thereofInfo
- Publication number
- SG11202108922WA SG11202108922WA SG11202108922WA SG11202108922WA SG11202108922WA SG 11202108922W A SG11202108922W A SG 11202108922WA SG 11202108922W A SG11202108922W A SG 11202108922WA SG 11202108922W A SG11202108922W A SG 11202108922WA SG 11202108922W A SG11202108922W A SG 11202108922WA
- Authority
- SG
- Singapore
- Prior art keywords
- piezo1
- variants
- ion channel
- channel component
- piezo type
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
- A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
- A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1096—Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962806932P | 2019-02-18 | 2019-02-18 | |
| US201962862847P | 2019-06-18 | 2019-06-18 | |
| PCT/US2020/017267 WO2020171982A1 (en) | 2019-02-18 | 2020-02-07 | Piezo type mechanosensitive ion channel component 1 (piezo1) variants and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202108922WA true SG11202108922WA (en) | 2021-09-29 |
Family
ID=69771182
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202108922WA SG11202108922WA (en) | 2019-02-18 | 2020-02-07 | Piezo type mechanosensitive ion channel component 1 (piezo1) variants and uses thereof |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11584966B2 (zh) |
| EP (2) | EP4317456A3 (zh) |
| JP (1) | JP2022520659A (zh) |
| KR (1) | KR20210136038A (zh) |
| CN (1) | CN113661252A (zh) |
| AU (1) | AU2020225197A1 (zh) |
| CA (1) | CA3130320A1 (zh) |
| FI (1) | FI3927844T3 (zh) |
| IL (1) | IL285644A (zh) |
| MX (1) | MX2021009983A (zh) |
| SG (1) | SG11202108922WA (zh) |
| WO (1) | WO2020171982A1 (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11584966B2 (en) | 2019-02-18 | 2023-02-21 | Regeneran Pharmaceuticals, Inc. | Piezo type mechanosensitive ion channel component 1 (PIEZO1) variants and uses thereof |
| CA3225855A1 (en) * | 2021-07-08 | 2023-01-12 | Regeneron Pharmaceuticals, Inc. | Treatment of varicose veins with piezo type mechanosensitive ion channel component 1 (piezo1) agonists |
| CN115120723B (zh) * | 2022-05-09 | 2023-05-26 | 浙江大学 | 巨噬细胞Piezo1敲除在促进缺血组织血管新生中的应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11584966B2 (en) * | 2019-02-18 | 2023-02-21 | Regeneran Pharmaceuticals, Inc. | Piezo type mechanosensitive ion channel component 1 (PIEZO1) variants and uses thereof |
-
2020
- 2020-02-07 US US16/785,152 patent/US11584966B2/en active Active
- 2020-02-07 AU AU2020225197A patent/AU2020225197A1/en active Pending
- 2020-02-07 SG SG11202108922WA patent/SG11202108922WA/en unknown
- 2020-02-07 EP EP23196219.2A patent/EP4317456A3/en active Pending
- 2020-02-07 KR KR1020217030162A patent/KR20210136038A/ko unknown
- 2020-02-07 EP EP20709947.4A patent/EP3927844B1/en active Active
- 2020-02-07 CA CA3130320A patent/CA3130320A1/en active Pending
- 2020-02-07 MX MX2021009983A patent/MX2021009983A/es unknown
- 2020-02-07 WO PCT/US2020/017267 patent/WO2020171982A1/en unknown
- 2020-02-07 CN CN202080026940.1A patent/CN113661252A/zh active Pending
- 2020-02-07 FI FIEP20709947.4T patent/FI3927844T3/fi active
- 2020-02-07 JP JP2021547854A patent/JP2022520659A/ja active Pending
-
2021
- 2021-08-16 IL IL285644A patent/IL285644A/en unknown
-
2023
- 2023-01-12 US US18/096,232 patent/US20230287502A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4317456A2 (en) | 2024-02-07 |
| US11584966B2 (en) | 2023-02-21 |
| CA3130320A1 (en) | 2020-08-27 |
| US20230287502A1 (en) | 2023-09-14 |
| CN113661252A (zh) | 2021-11-16 |
| IL285644A (en) | 2021-09-30 |
| EP4317456A3 (en) | 2024-04-24 |
| EP3927844A1 (en) | 2021-12-29 |
| EP3927844B1 (en) | 2024-03-27 |
| KR20210136038A (ko) | 2021-11-16 |
| WO2020171982A1 (en) | 2020-08-27 |
| AU2020225197A8 (en) | 2021-10-07 |
| FI3927844T3 (fi) | 2024-05-27 |
| US20200263252A1 (en) | 2020-08-20 |
| AU2020225197A1 (en) | 2021-09-16 |
| MX2021009983A (es) | 2021-12-10 |
| JP2022520659A (ja) | 2022-03-31 |
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