SG11202108312PA - Method of safe administration of phosphorylated tau peptide vaccine - Google Patents

Method of safe administration of phosphorylated tau peptide vaccine

Info

Publication number
SG11202108312PA
SG11202108312PA SG11202108312PA SG11202108312PA SG11202108312PA SG 11202108312P A SG11202108312P A SG 11202108312PA SG 11202108312P A SG11202108312P A SG 11202108312PA SG 11202108312P A SG11202108312P A SG 11202108312PA SG 11202108312P A SG11202108312P A SG 11202108312PA
Authority
SG
Singapore
Prior art keywords
peptide vaccine
phosphorylated tau
tau peptide
safe administration
administration
Prior art date
Application number
SG11202108312PA
Other languages
English (en)
Inventor
Andrea Pfeifer
Andreas Muhs
Bosch Maria Pihlgren
Verhille Marija Vukicevic
Nicolas Piot
Saroj Raj Ghimire
Elizabeth Anne Ramsburg
Marco Donata De
Charlotte Sadaka
Original Assignee
Ac Immune Sa
Janssen Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ac Immune Sa, Janssen Pharmaceuticals Inc filed Critical Ac Immune Sa
Publication of SG11202108312PA publication Critical patent/SG11202108312PA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0007—Nervous system antigens; Prions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55516—Proteins; Peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6018—Lipids, e.g. in lipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
    • A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
SG11202108312PA 2019-02-08 2020-02-07 Method of safe administration of phosphorylated tau peptide vaccine SG11202108312PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962802870P 2019-02-08 2019-02-08
PCT/US2020/017235 WO2020163730A2 (en) 2019-02-08 2020-02-07 Method of safe administration of phosphorylated tau peptide vaccine

Publications (1)

Publication Number Publication Date
SG11202108312PA true SG11202108312PA (en) 2021-08-30

Family

ID=69780323

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202108312PA SG11202108312PA (en) 2019-02-08 2020-02-07 Method of safe administration of phosphorylated tau peptide vaccine

Country Status (17)

Country Link
US (3) US11684576B2 (enExample)
EP (1) EP3920966A2 (enExample)
JP (2) JP7541527B2 (enExample)
KR (1) KR20210125048A (enExample)
CN (1) CN113710269A (enExample)
AU (1) AU2020219804A1 (enExample)
BR (1) BR112021014794A2 (enExample)
CA (1) CA3129252A1 (enExample)
EA (1) EA202192203A1 (enExample)
IL (1) IL285163B2 (enExample)
JO (1) JOP20210211A1 (enExample)
MX (1) MX2021009508A (enExample)
MY (1) MY206596A (enExample)
PH (1) PH12021551876A1 (enExample)
SG (1) SG11202108312PA (enExample)
TW (1) TWI868106B (enExample)
WO (1) WO2020163730A2 (enExample)

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CA3228878A1 (en) * 2021-08-12 2023-02-16 Andrea Pfeifer Liposomes containing phosphorylated tau peptides for inducing sustained immune responses
US20250134991A1 (en) * 2021-08-20 2025-05-01 Thomas Jefferson University Monophosphoryl lipid adjuvant (mpla) compositions, vaccine compositions thereof, and methods of preparing and using the same

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Also Published As

Publication number Publication date
WO2020163730A2 (en) 2020-08-13
US12324855B2 (en) 2025-06-10
US20230381108A1 (en) 2023-11-30
MY206596A (en) 2024-12-25
CN113710269A (zh) 2021-11-26
US20200253873A1 (en) 2020-08-13
BR112021014794A2 (pt) 2021-10-05
TWI868106B (zh) 2025-01-01
JP2022520060A (ja) 2022-03-28
KR20210125048A (ko) 2021-10-15
PH12021551876A1 (en) 2022-05-23
US20250275920A1 (en) 2025-09-04
EA202192203A1 (ru) 2021-10-20
IL285163B2 (en) 2025-05-01
AU2020219804A1 (en) 2021-08-19
MX2021009508A (es) 2021-09-08
JOP20210211A1 (ar) 2023-01-30
TW202045204A (zh) 2020-12-16
IL285163B1 (en) 2025-01-01
EP3920966A2 (en) 2021-12-15
IL285163A (en) 2021-09-30
JP2024178161A (ja) 2024-12-24
WO2020163730A3 (en) 2020-09-24
US11684576B2 (en) 2023-06-27
CA3129252A1 (en) 2020-08-13
JP7541527B2 (ja) 2024-08-28

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