SG11202107925YA - Pyrrolopyrimidine derivative and use thereof - Google Patents

Pyrrolopyrimidine derivative and use thereof

Info

Publication number
SG11202107925YA
SG11202107925YA SG11202107925YA SG11202107925YA SG11202107925YA SG 11202107925Y A SG11202107925Y A SG 11202107925YA SG 11202107925Y A SG11202107925Y A SG 11202107925YA SG 11202107925Y A SG11202107925Y A SG 11202107925YA SG 11202107925Y A SG11202107925Y A SG 11202107925YA
Authority
SG
Singapore
Prior art keywords
pyrrolopyrimidine derivative
pyrrolopyrimidine
derivative
Prior art date
Application number
SG11202107925YA
Other languages
English (en)
Inventor
Xuejun Zhang
Dabing Ye
Lie Li
Jie Shen
Xiaohua Ding
Hongna Sun
Zhe Liu
Yang Zang
Yonggang Wei
Original Assignee
Wuhan Humanwell Innovative Drug Res And Development Center Limited Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuhan Humanwell Innovative Drug Res And Development Center Limited Company filed Critical Wuhan Humanwell Innovative Drug Res And Development Center Limited Company
Publication of SG11202107925YA publication Critical patent/SG11202107925YA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Transplantation (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11202107925YA 2019-02-01 2020-01-22 Pyrrolopyrimidine derivative and use thereof SG11202107925YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201910106140 2019-02-01
CN201910572538 2019-06-26
PCT/CN2020/073859 WO2020156459A1 (zh) 2019-02-01 2020-01-22 吡咯并嘧啶衍生物及其用途

Publications (1)

Publication Number Publication Date
SG11202107925YA true SG11202107925YA (en) 2021-08-30

Family

ID=71841643

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202107925YA SG11202107925YA (en) 2019-02-01 2020-01-22 Pyrrolopyrimidine derivative and use thereof

Country Status (12)

Country Link
US (1) US20220064172A1 (de)
EP (1) EP3919498B3 (de)
JP (1) JP7228702B2 (de)
KR (1) KR102629358B1 (de)
CN (1) CN111518101B (de)
AU (1) AU2020213569B2 (de)
BR (1) BR112021014777A2 (de)
CA (1) CA3126176C (de)
DK (1) DK3919498T6 (de)
IL (1) IL284994B2 (de)
SG (1) SG11202107925YA (de)
WO (1) WO2020156459A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112022004099A2 (pt) * 2019-09-06 2022-05-31 Wuhan Humanwell Innovative Drug Res And Development Center Limited Company Composto, composição farmacêutica, uso do composto, e, método para o tratamento de uma doença relacionada ao atx
JP2023535846A (ja) * 2020-07-28 2023-08-21 武漢人福創新薬物研発中心有限公司 含窒素複素環化合物の塩及びその塩の固体形態、医薬組成物並びに用途
CN113999235A (zh) * 2020-07-28 2022-02-01 武汉人福创新药物研发中心有限公司 含氮杂环化合物的固体形式及其药物组合物和用途
US11977085B1 (en) 2023-09-05 2024-05-07 Elan Ehrlich Date rape drug detection device and method of using same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140008987A (ko) 2012-07-13 2014-01-22 삼성전자주식회사 필기 이미지 인식을 이용한 어플리케이션 제어 방법 및 장치
TWI499591B (zh) * 2013-01-11 2015-09-11 Lilly Co Eli 雙環嘧啶化合物
TW201520219A (zh) * 2013-03-12 2015-06-01 Lilly Co Eli 咪唑並吡啶化合物
JP6435323B2 (ja) 2013-06-19 2018-12-05 ガラパゴス・ナムローゼ・フェンノートシャップGalapagos N.V. 炎症性障害の治療のための新規化合物及びその医薬組成物

Also Published As

Publication number Publication date
KR20210108985A (ko) 2021-09-03
JP2022518224A (ja) 2022-03-14
CN111518101A (zh) 2020-08-11
EP3919498B3 (de) 2024-09-04
JP7228702B2 (ja) 2023-02-24
AU2020213569B2 (en) 2022-10-13
EP3919498A1 (de) 2021-12-08
US20220064172A1 (en) 2022-03-03
BR112021014777A2 (pt) 2021-09-28
EP3919498B1 (de) 2024-07-03
IL284994A (en) 2021-09-30
IL284994B2 (en) 2024-10-01
CA3126176C (en) 2023-08-29
CA3126176A1 (en) 2020-08-06
AU2020213569A1 (en) 2021-08-05
DK3919498T6 (da) 2024-10-07
KR102629358B1 (ko) 2024-01-24
NZ778087A (en) 2024-02-23
IL284994B1 (en) 2024-06-01
CN111518101B (zh) 2022-07-29
WO2020156459A1 (zh) 2020-08-06
EP3919498A4 (de) 2022-09-28

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