SG11202105965PA - Linear solution phase routes for wnt hexapeptides - Google Patents

Linear solution phase routes for wnt hexapeptides

Info

Publication number
SG11202105965PA
SG11202105965PA SG11202105965PA SG11202105965PA SG11202105965PA SG 11202105965P A SG11202105965P A SG 11202105965PA SG 11202105965P A SG11202105965P A SG 11202105965PA SG 11202105965P A SG11202105965P A SG 11202105965PA SG 11202105965P A SG11202105965P A SG 11202105965PA
Authority
SG
Singapore
Prior art keywords
hexapeptides
wnt
solution phase
linear solution
phase routes
Prior art date
Application number
SG11202105965PA
Other languages
English (en)
Inventor
Pratap Tadikonda Veerabhadra
Rao Kamaraju Raghavendra
Dennis Henriksen
Original Assignee
Wntresearch Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wntresearch Ab filed Critical Wntresearch Ab
Publication of SG11202105965PA publication Critical patent/SG11202105965PA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202105965PA 2018-12-14 2019-12-02 Linear solution phase routes for wnt hexapeptides SG11202105965PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18212658.1A EP3666789A1 (en) 2018-12-14 2018-12-14 Linear solution phase routes for wnt hexapeptides
PCT/EP2019/083309 WO2020120198A1 (en) 2018-12-14 2019-12-02 Linear solution phase routes for wnt hexapeptides

Publications (1)

Publication Number Publication Date
SG11202105965PA true SG11202105965PA (en) 2021-07-29

Family

ID=65010407

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202105965PA SG11202105965PA (en) 2018-12-14 2019-12-02 Linear solution phase routes for wnt hexapeptides

Country Status (17)

Country Link
US (1) US20220017568A1 (zh)
EP (2) EP3666789A1 (zh)
JP (1) JP7362148B2 (zh)
KR (1) KR20210112331A (zh)
CN (1) CN113646324B (zh)
AU (1) AU2019395708A1 (zh)
BR (1) BR112021011318A2 (zh)
CA (1) CA3123331C (zh)
CL (1) CL2021001532A1 (zh)
DK (1) DK3894426T3 (zh)
ES (1) ES2934161T3 (zh)
FI (1) FI3894426T3 (zh)
HU (1) HUE061310T2 (zh)
MX (1) MX2021006809A (zh)
PL (1) PL3894426T3 (zh)
SG (1) SG11202105965PA (zh)
WO (1) WO2020120198A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2969155T3 (es) 2021-12-10 2024-05-16 Wntresearch Ab Composiciones estables del hexapéptido Foxy-5 con alta solubilidad que comprenden una base nitrogenada

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1888628B1 (en) 2005-05-30 2014-11-12 Wntresearch AB A peptide ligand to impair cancer cell migration
CN102056939A (zh) * 2008-04-30 2011-05-11 温特研究公司 雌激素受体-α的活性的恢复
AU2009282525A1 (en) * 2008-08-13 2010-02-18 Wntresearch Ab The use of Wnt5-a peptide derivates for the treatment of melanoma and gastric cancer
EP3229831B1 (en) * 2014-12-10 2020-03-11 Hyperstem SA Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brain tumors
CN105111303B (zh) * 2015-06-23 2019-07-26 济南康和医药科技有限公司 一种固液结合制备利拉鲁肽的方法
EP3613757A1 (en) * 2018-08-20 2020-02-26 Wntresearch AB Solution phase routes for wnt hexapeptides

Also Published As

Publication number Publication date
CA3123331C (en) 2023-12-05
HUE061310T2 (hu) 2023-06-28
JP2022513474A (ja) 2022-02-08
KR20210112331A (ko) 2021-09-14
ES2934161T3 (es) 2023-02-17
DK3894426T3 (da) 2022-12-19
FI3894426T3 (fi) 2023-01-13
MX2021006809A (es) 2021-08-24
PL3894426T3 (pl) 2023-03-13
CA3123331A1 (en) 2020-06-18
EP3894426B1 (en) 2022-09-21
WO2020120198A1 (en) 2020-06-18
AU2019395708A1 (en) 2021-06-24
US20220017568A1 (en) 2022-01-20
JP7362148B2 (ja) 2023-10-17
EP3894426A1 (en) 2021-10-20
BR112021011318A2 (pt) 2021-11-30
CN113646324A (zh) 2021-11-12
CN113646324B (zh) 2024-03-29
CL2021001532A1 (es) 2021-12-31
WO2020120198A8 (en) 2021-10-28
EP3666789A1 (en) 2020-06-17

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