SG11202101590UA - Solution phase routes for wnt hexapeptides - Google Patents
Solution phase routes for wnt hexapeptidesInfo
- Publication number
- SG11202101590UA SG11202101590UA SG11202101590UA SG11202101590UA SG11202101590UA SG 11202101590U A SG11202101590U A SG 11202101590UA SG 11202101590U A SG11202101590U A SG 11202101590UA SG 11202101590U A SG11202101590U A SG 11202101590UA SG 11202101590U A SG11202101590U A SG 11202101590UA
- Authority
- SG
- Singapore
- Prior art keywords
- hexapeptides
- wnt
- solution phase
- phase routes
- routes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
- C07K5/081—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing O or S as heteroatoms, e.g. Cys, Ser
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18189699.4A EP3613757A1 (en) | 2018-08-20 | 2018-08-20 | Solution phase routes for wnt hexapeptides |
| PCT/EP2019/072122 WO2020038878A1 (en) | 2018-08-20 | 2019-08-19 | Solution phase routes for wnt hexapeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202101590UA true SG11202101590UA (en) | 2021-03-30 |
Family
ID=63490194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202101590UA SG11202101590UA (en) | 2018-08-20 | 2019-08-19 | Solution phase routes for wnt hexapeptides |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11912791B2 (en) |
| EP (2) | EP3613757A1 (en) |
| JP (1) | JP2021534199A (en) |
| KR (1) | KR20210046730A (en) |
| CN (1) | CN112638934B (en) |
| AU (1) | AU2019323613B2 (en) |
| BR (1) | BR112021003015A2 (en) |
| CA (1) | CA3110128A1 (en) |
| ES (1) | ES2958219T3 (en) |
| HU (1) | HUE063279T2 (en) |
| PL (1) | PL3841107T3 (en) |
| SG (1) | SG11202101590UA (en) |
| WO (1) | WO2020038878A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3666789A1 (en) * | 2018-12-14 | 2020-06-17 | Wntresearch AB | Linear solution phase routes for wnt hexapeptides |
| ES2969155T3 (en) | 2021-12-10 | 2024-05-16 | Wntresearch Ab | Stable Foxy-5 hexapeptide compositions with high solubility comprising a nitrogenous base |
| CN117567566B (en) * | 2023-11-28 | 2024-05-03 | 山东济肽生物科技有限公司 | Liquid phase synthesis process of cyclohexapeptide-9 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5086042A (en) * | 1985-12-19 | 1992-02-04 | Fisons Corporation | Peptides with sulfate ester groups |
| EP1701969B1 (en) * | 2003-12-31 | 2007-10-24 | F.Hoffmann-La Roche Ag | Process for peptide synthesis using a reduced amount of deprotection agent |
| EP1888628B1 (en) | 2005-05-30 | 2014-11-12 | Wntresearch AB | A peptide ligand to impair cancer cell migration |
| EP3229831B1 (en) * | 2014-12-10 | 2020-03-11 | Hyperstem SA | Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brain tumors |
| EP3274360B1 (en) * | 2015-03-26 | 2020-05-06 | Amgen Inc. | Solution phase method for preparing etelcalcetide |
-
2018
- 2018-08-20 EP EP18189699.4A patent/EP3613757A1/en not_active Withdrawn
-
2019
- 2019-08-19 CA CA3110128A patent/CA3110128A1/en active Pending
- 2019-08-19 EP EP19753112.2A patent/EP3841107B1/en active Active
- 2019-08-19 KR KR1020217008318A patent/KR20210046730A/en active Search and Examination
- 2019-08-19 BR BR112021003015-8A patent/BR112021003015A2/en unknown
- 2019-08-19 JP JP2021509841A patent/JP2021534199A/en active Pending
- 2019-08-19 PL PL19753112.2T patent/PL3841107T3/en unknown
- 2019-08-19 US US17/267,764 patent/US11912791B2/en active Active
- 2019-08-19 SG SG11202101590UA patent/SG11202101590UA/en unknown
- 2019-08-19 CN CN201980054547.0A patent/CN112638934B/en active Active
- 2019-08-19 ES ES19753112T patent/ES2958219T3/en active Active
- 2019-08-19 AU AU2019323613A patent/AU2019323613B2/en active Active
- 2019-08-19 HU HUE19753112A patent/HUE063279T2/en unknown
- 2019-08-19 WO PCT/EP2019/072122 patent/WO2020038878A1/en active Search and Examination
-
2023
- 2023-03-15 US US18/184,605 patent/US11970551B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020038878A1 (en) | 2020-02-27 |
| AU2019323613A1 (en) | 2021-03-04 |
| AU2019323613B2 (en) | 2024-04-18 |
| ES2958219T3 (en) | 2024-02-05 |
| EP3841107A1 (en) | 2021-06-30 |
| PL3841107T3 (en) | 2024-02-05 |
| US20210171575A1 (en) | 2021-06-10 |
| CN112638934A (en) | 2021-04-09 |
| HUE063279T2 (en) | 2024-01-28 |
| KR20210046730A (en) | 2021-04-28 |
| EP3841107B1 (en) | 2023-06-28 |
| US20230295232A1 (en) | 2023-09-21 |
| BR112021003015A2 (en) | 2021-05-11 |
| JP2021534199A (en) | 2021-12-09 |
| EP3613757A1 (en) | 2020-02-26 |
| EP3841107C0 (en) | 2023-06-28 |
| CN112638934B (en) | 2024-06-11 |
| US11912791B2 (en) | 2024-02-27 |
| CA3110128A1 (en) | 2020-02-27 |
| US11970551B2 (en) | 2024-04-30 |
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