SG11202104619WA - Compositions, methods and systems for protein corona analysis and uses thereof - Google Patents

Compositions, methods and systems for protein corona analysis and uses thereof

Info

Publication number
SG11202104619WA
SG11202104619WA SG11202104619WA SG11202104619WA SG11202104619WA SG 11202104619W A SG11202104619W A SG 11202104619WA SG 11202104619W A SG11202104619W A SG 11202104619WA SG 11202104619W A SG11202104619W A SG 11202104619WA SG 11202104619W A SG11202104619W A SG 11202104619WA
Authority
SG
Singapore
Prior art keywords
compositions
systems
methods
protein corona
corona analysis
Prior art date
Application number
SG11202104619WA
Other languages
English (en)
Inventor
Hongwei Xia
Lyndal Hesterberg
Michael Figa
Xiaoyan Zhao
Gregory Troiano
William Manning
John Blume
Omid Farokhzad
Matthew Mclean
Marwin Ko
Craig Stolarczyk
Theodore Platt
Original Assignee
Seer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seer Inc filed Critical Seer Inc
Publication of SG11202104619WA publication Critical patent/SG11202104619WA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00Magnetic particle immunoreagent carriers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Nanotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG11202104619WA 2018-11-07 2019-11-07 Compositions, methods and systems for protein corona analysis and uses thereof SG11202104619WA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862756960P 2018-11-07 2018-11-07
US201962824278P 2019-03-26 2019-03-26
US201962874862P 2019-07-16 2019-07-16
PCT/US2019/000061 WO2020096631A2 (en) 2018-11-07 2019-11-07 Compositions, methods and systems for protein corona analysis and uses thereof

Publications (1)

Publication Number Publication Date
SG11202104619WA true SG11202104619WA (en) 2021-06-29

Family

ID=70612108

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104619WA SG11202104619WA (en) 2018-11-07 2019-11-07 Compositions, methods and systems for protein corona analysis and uses thereof

Country Status (13)

Country Link
US (3) US20210215685A1 (ko)
EP (1) EP3877400A4 (ko)
JP (2) JP7236539B2 (ko)
KR (2) KR20230155589A (ko)
CN (1) CN113412274A (ko)
AU (1) AU2019374692A1 (ko)
BR (1) BR112021008999A2 (ko)
CA (1) CA3118666A1 (ko)
GB (1) GB2595583A (ko)
IL (1) IL282981A (ko)
MX (1) MX2021005353A (ko)
SG (1) SG11202104619WA (ko)
WO (1) WO2020096631A2 (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112021008999A2 (pt) 2018-11-07 2021-08-10 Seer, Inc. composições, métodos e sistemas para a análise de proteína corona e seus usos.
AU2020247907A1 (en) * 2019-03-26 2021-10-28 Seer, Inc. Compositions, methods and systems for protein corona analysis from biofluids and uses thereof
CN117233413A (zh) 2019-08-05 2023-12-15 禧尔公司 用于样品制备、数据生成和蛋白质冠分析的系统和方法
EP4096694A4 (en) 2020-01-30 2024-01-24 Prognomiq Inc LUNG BIOMARKERS AND METHODS OF USE THEREOF
EP4182474A1 (en) * 2020-07-20 2023-05-24 Seer, Inc. Particles and methods of assaying
GB202012434D0 (en) * 2020-08-10 2020-09-23 Univ Manchester Multiomic analysis of nanoparticle-coronas
CA3190719A1 (en) * 2020-08-25 2022-03-03 Daniel Hornburg Compositions and methods for assaying proteins and nucleic acids
CN117580584A (zh) * 2021-04-29 2024-02-20 禧尔公司 用于富集特定蛋白质子集的肽修饰纳米颗粒
WO2023141580A2 (en) * 2022-01-20 2023-07-27 Seer, Inc. Particles and methods of assaying
CN114113287A (zh) * 2022-01-25 2022-03-01 北京青莲百奥生物科技有限公司 一种血清蛋白制备方法及血清蛋白质组质谱检测方法
CN114791466A (zh) * 2022-03-10 2022-07-26 中国中医科学院中药研究所 一种基于蛋白冠的血清高丰度蛋白去除方法
WO2023245075A2 (en) * 2022-06-15 2023-12-21 Seer, Inc. Systems and methods for biomolecule assays
GB2620799A (en) * 2022-07-22 2024-01-24 Life Tech As Particles

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5498545A (en) 1994-07-21 1996-03-12 Vestal; Marvin L. Mass spectrometer system and method for matrix-assisted laser desorption measurements
US6361944B1 (en) 1996-07-29 2002-03-26 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses therefor
US5928952A (en) 1997-11-05 1999-07-27 Zymark Corporation Scheduled system and method for processing chemical products
US6406921B1 (en) 1998-07-14 2002-06-18 Zyomyx, Incorporated Protein arrays for high-throughput screening
US6413780B1 (en) 1998-10-14 2002-07-02 Abbott Laboratories Structure and method for performing a determination of an item of interest in a sample
DE69941493D1 (de) 1998-11-16 2009-11-12 California Inst Of Techn Gleichzeitige bestimmung von gleichgewichts- und kinetischen eigenschaften
US20050148101A1 (en) 1999-01-23 2005-07-07 Bamdad Cynthia C. Interaction of colloid-immobilized species with species on non-colloidal structures
US20020009394A1 (en) 1999-04-02 2002-01-24 Hubert Koster Automated process line
US6969615B2 (en) 1999-07-26 2005-11-29 20/20 Genesystems, Inc. Methods, devices, arrays and kits for detecting and analyzing biomolecules
EP1311839B1 (en) 2000-06-21 2006-03-01 Bioarray Solutions Ltd Multianalyte molecular analysis using application-specific random particle arrays
US20050053999A1 (en) 2000-11-14 2005-03-10 Gough David A. Method for predicting G-protein coupled receptor-ligand interactions
US6649419B1 (en) * 2000-11-28 2003-11-18 Large Scale Proteomics Corp. Method and apparatus for protein manipulation
US6780602B2 (en) 2001-11-01 2004-08-24 Microbiosystems, Limited Partnership Taxonomic identification of pathogenic microorganisms and their toxic proteins
WO2003090897A1 (en) 2002-04-26 2003-11-06 Abbott Laboratories Structure and method for handling magnetic particles in biological assays
EP1552302B1 (en) 2002-07-24 2009-03-25 Bio-Rad Laboratories, Inc. Protein interaction difference mapping
US7960184B2 (en) 2002-09-20 2011-06-14 George Mason Intellectual Properties, Inc. Methods and devices for active bioassay
EP2413136B1 (en) * 2003-07-18 2013-07-03 Bio-Rad Laboratories, Inc. System and method for multi-analyte detection
EP1580559B1 (en) * 2004-03-23 2013-12-25 Bio-Rad Laboratories, Inc. Methods for reducing the variance between analyte concentrations taken from complex sample mixtures
WO2006032044A2 (en) 2004-09-15 2006-03-23 Microchip Biotechnologies, Inc. Microfluidic devices
DE102004051785B4 (de) 2004-10-25 2008-04-24 Bruker Daltonik Gmbh Proteinprofile mit Luft-MALDI
US9002652B1 (en) 2005-01-27 2015-04-07 Institute For Systems Biology Methods for identifying and using organ-specific proteins in blood
EP1869230B1 (en) 2005-03-23 2017-08-30 Bio-Rad Laboratories, Inc. Method for purifying proteins
CA2602951A1 (en) 2005-03-23 2006-09-28 Bio-Rad Laboratories, Inc. Diverse chemical libraries bound to small particles with paramagnetic properties
US9588124B2 (en) 2005-05-11 2017-03-07 Georgia Tech Research Corporation Shape tunable plasmonic nanoparticles
KR20080028886A (ko) 2005-05-26 2008-04-02 앙상블 디스커버리 코포레이션 핵산-템플레이팅된 화학 반응에 의한 생검출
GB0514910D0 (en) 2005-07-20 2005-08-24 Solexa Ltd Method for sequencing a polynucleotide template
WO2007070682A2 (en) 2005-12-15 2007-06-21 Massachusetts Institute Of Technology System for screening particles
US9347945B2 (en) 2005-12-22 2016-05-24 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
US20070178504A1 (en) 2005-12-22 2007-08-02 Tracey Colpitts Methods and marker combinations for screening for predisposition to lung cancer
CN100374857C (zh) * 2006-01-26 2008-03-12 复旦大学 快速富集痕量多肽或蛋白质并实现鉴定的方法
EP1979079A4 (en) 2006-02-03 2012-11-28 Integenx Inc MICROFLUIDIC DEVICES
EP1987159B2 (en) 2006-02-08 2020-08-12 Illumina Cambridge Limited Method for sequencing a polynucleotide template
EP1882948A2 (de) 2006-07-28 2008-01-30 Qiagen GmbH Vorrichtung zur Probenverarbeitung
WO2008073168A2 (en) 2006-08-25 2008-06-19 The Trustees Of Columbia University In The City Of New York Systems and methods for high-throughput radiation biodosimetry
US20100285490A1 (en) 2006-12-29 2010-11-11 Invitrogen Corporation Detection apparatus
US7815803B2 (en) 2007-06-14 2010-10-19 Roche Diagnostics Operations, Inc. Preparation of samples for LC-MS/MS using magnetic particles
KR20100098500A (ko) 2007-10-05 2010-09-07 국립대학법인 홋가이도 다이가쿠 당쇄 자동 전처리 장치
PT2209893E (pt) 2007-10-12 2014-02-26 Pronota Nv Uso de aptâmeros em proteómica
US8021891B2 (en) 2007-11-28 2011-09-20 University Of Massachusetts Methods and compositions for protein detection using nanoparticle-fluorescent polymer complexes
US20100291224A1 (en) 2008-01-03 2010-11-18 Yen Wah Tong Nanostructures, methods of preparing and uses thereof
US20090253181A1 (en) 2008-01-22 2009-10-08 Microchip Biotechnologies, Inc. Universal sample preparation system and use in an integrated analysis system
KR101039629B1 (ko) 2008-05-22 2011-06-08 성균관대학교산학협력단 생체물질의 검출방법, 생체물질 검출용 칩의 제조방법 및생물질 검출용 칩
WO2010042555A2 (en) 2008-10-06 2010-04-15 The Brigham And Women's Hospital, Inc. Particles with multiple functionalized surface domains
WO2010078601A1 (en) 2009-01-05 2010-07-08 The Regents Of The University Of California High throughput biomolecule separation and analysis
EP2394175B1 (en) * 2009-02-09 2016-02-03 caprotec bioanalytics GmbH Devices, systems and methods for separating magnetic particles
WO2010096323A1 (en) 2009-02-18 2010-08-26 Streck, Inc. Preservation of cell-free nucleic acids
WO2010097785A1 (en) * 2009-02-26 2010-09-02 University College Dublin, National University Of Ireland, Dublin A method for the selective concentration of a specific low abundance biomolecule
JP6059014B2 (ja) 2009-06-19 2017-01-11 アリゾナ ボード オブ リージェンツ ア ボディー コーポレート アクティング オン ビハーフ オブ アリゾナ ステイト ユニバーシティARIZONA BOARD OF REGENTS,a body corporate acting on behalf of ARIZONA STATE UNIVERSITY 試料の構成成分の検出において使用されるデバイスを製造する方法およびペプチドアレイ
US9217747B2 (en) 2009-10-29 2015-12-22 Health Diagnostic Laboratory, Inc. Protein and lipid biomarkers providing consistent improvement to the prediction of type 2 diabetes
WO2011088128A2 (en) 2010-01-14 2011-07-21 University Of Central Florida Research Foundation, Inc. Methods for biomolecule and biomolecule complex (bmc) detection and analysis and the use of such for research and medical diagnosis
KR101824746B1 (ko) 2010-02-10 2018-02-01 더 리젠츠 오브 더 유니버시티 오브 캘리포니아 폐암 검출용 타액 바이오마커
JP5755732B2 (ja) 2010-06-10 2015-07-29 ミダテック リミテッド ペプチド担持ナノ粒子
US9549901B2 (en) 2010-09-03 2017-01-24 The Brigham And Women's Hospital, Inc. Lipid-polymer hybrid particles
US9329176B2 (en) 2010-11-18 2016-05-03 Academia Sinica Glycopeptide-functionalized nanoparticles arrays for capturing and detecting biomolecules
US10144950B2 (en) 2011-01-31 2018-12-04 Roche Sequencing Solutions, Inc. Methods of identifying multiple epitopes in cells
GB201103726D0 (en) 2011-03-04 2011-04-20 Immunovia Ab Method, array and use thereof
US20130058923A1 (en) 2011-08-03 2013-03-07 Qun Huo Biomolecular interactions and interaction products as biomarkers for detection, diagnosis, prognosis and predicting therapeutic responses of human diseases
CA2844671A1 (en) 2011-08-08 2013-02-14 Caris Life Sciences Luxembourg Holdings, S.A.R.L. Biomarker compositions and methods
US10444245B2 (en) 2012-05-24 2019-10-15 Vib Vzw Trapping mammalian protein-protein complexes in virus-like particles utilizing HIV-1 GAG-bait fusion proteins
CN102798658A (zh) * 2012-07-20 2012-11-28 浙江大学 血清中低丰度低分子量蛋白的分析方法
EP2880475B1 (en) 2012-07-30 2023-10-18 3M Innovative Properties Company UV STABLE ASSEMBLIES COMPRISING MULTI-LAYER OPTICAL FILMs
US20140194315A1 (en) 2013-01-08 2014-07-10 Albert Einstein College Of Medicine Of Yeshiva University Methods and compositions for rapid functional analysis of gene variants
CA2938907A1 (en) 2014-02-07 2015-08-13 European Molecular Biology Laboratory Proteomic sample preparation using paramagnetic beads
ES2676553T3 (es) 2014-03-26 2018-07-20 F. Hoffmann-La Roche Ag IGFBP7 para el diagnóstico de la disfunción diastólica
EP2957912A1 (en) 2014-06-17 2015-12-23 University College Dublin A method of labelling a target molecule forming part of a corona of molecules on a surface of a nanosized object
US10272050B2 (en) 2014-10-14 2019-04-30 The Brigham And Women's Hospital, Inc. Nanoparticles and methods of use
CN105771942B (zh) * 2014-12-26 2018-06-29 中国科学院大连化学物理研究所 一种磁性纳米材料及其制备与应用
TWI547693B (zh) 2015-05-07 2016-09-01 希華晶體科技股份有限公司 感測方法及感測晶片
US10900975B2 (en) 2015-05-12 2021-01-26 Arizona Board Of Regents On Behalf Of Arizona State University Systems and methods of epitope binning and antibody profiling
CN105126736A (zh) * 2015-07-23 2015-12-09 江苏大学 环氧基磁性纳米硅球的制备方法及其应用
WO2017091631A1 (en) 2015-11-23 2017-06-01 Massachusetts Institute Of Technology Protein corona phase molecular recognition
EP3386551A4 (en) 2015-12-11 2018-10-24 The General Hospital Corporation Dextran nanoparticles for macrophage specific imaging and therapy
CN106268707B (zh) * 2016-08-11 2018-08-28 北京蛋白质组研究中心 一种基于磁性多孔材料的磷酸肽富集新方法
GB201615128D0 (en) 2016-09-06 2016-10-19 Univ Manchester Methods
CN106432644B (zh) * 2016-09-23 2018-09-07 河南中医药大学 一种亲水型聚合物功能化磁性纳米微球及其制备方法和应用
JP2020514746A (ja) 2016-12-01 2020-05-21 ノーティラス バイオテクノロジー インコーポレイテッド タンパク質をアッセイする方法
US20210072255A1 (en) 2016-12-16 2021-03-11 The Brigham And Women's Hospital, Inc. System and method for protein corona sensor array for early detection of diseases
DE202017007366U1 (de) 2016-12-16 2021-02-17 The Brigham And Women's Hospital, Inc. Sensor-Array zum Erfassen einer relativen Proteinkonzentration
EP3701066A4 (en) 2017-10-23 2021-08-11 Nautilus Biotechnology, Inc. PROTEINIDENTIFICATION PROCEDURES AND SYSTEMS
CN107991277B (zh) * 2017-11-27 2020-10-16 陕西中药研究所(陕西医药信息中心) 五羟色胺-磁性微粒复合物及富集唾液酸化糖蛋白的方法
JP7458678B2 (ja) 2017-12-29 2024-04-01 ノーティラス・サブシディアリー・インコーポレイテッド タンパク質同定のためのデコーディングアプローチ方法
BR112021008999A2 (pt) 2018-11-07 2021-08-10 Seer, Inc. composições, métodos e sistemas para a análise de proteína corona e seus usos.
AU2020247907A1 (en) 2019-03-26 2021-10-28 Seer, Inc. Compositions, methods and systems for protein corona analysis from biofluids and uses thereof
CN117233413A (zh) * 2019-08-05 2023-12-15 禧尔公司 用于样品制备、数据生成和蛋白质冠分析的系统和方法
WO2021087407A1 (en) * 2019-11-02 2021-05-06 Seer, Inc. Systems for protein corona analysis
EP4182474A1 (en) 2020-07-20 2023-05-24 Seer, Inc. Particles and methods of assaying

Also Published As

Publication number Publication date
EP3877400A4 (en) 2022-09-07
US20230417744A1 (en) 2023-12-28
KR102594366B1 (ko) 2023-10-27
WO2020096631A3 (en) 2020-06-25
JP2023065530A (ja) 2023-05-12
GB2595583A (en) 2021-12-01
KR20210113977A (ko) 2021-09-17
IL282981A (en) 2021-06-30
US20210285957A1 (en) 2021-09-16
MX2021005353A (es) 2021-09-23
CN113412274A (zh) 2021-09-17
CA3118666A1 (en) 2020-05-14
JP2022512961A (ja) 2022-02-07
AU2019374692A1 (en) 2021-06-03
US11428688B2 (en) 2022-08-30
EP3877400A2 (en) 2021-09-15
US20210215685A1 (en) 2021-07-15
JP7236539B2 (ja) 2023-03-09
KR20230155589A (ko) 2023-11-10
BR112021008999A2 (pt) 2021-08-10
WO2020096631A2 (en) 2020-05-14

Similar Documents

Publication Publication Date Title
IL282981A (en) Preparations, methods and systems for corona protein analysis and their uses
SG11202100588SA (en) Systems and methods for metabolome analysis
EP3610034A4 (en) SAMPLE PREPARATION SYSTEMS, METHODS AND COMPOSITIONS
HK1252955A1 (zh) 針對程序性死亡配體(pd-l1)的單域抗體及其衍生蛋白
EP3837527A4 (en) PARTICLE ANALYSIS SYSTEMS AND METHODS
MA41414A (fr) Protéines de liaison agonistes d' icos
EP3785269A4 (en) Methods and systems for analyzing microbiota
SG11201811762RA (en) Systems and methods for path determination
EP3701066A4 (en) PROTEINIDENTIFICATION PROCEDURES AND SYSTEMS
GB2592113B (en) Methods and systems for cytometry
EP3347695A4 (en) ANALYZE INSTRUMENT, APPROPRIATE SYSTEMS AND METHOD
EP3612641A4 (en) COMPOSITIONS AND PROCEDURES FOR LIBRARY CREATION AND SEQUENCE ANALYSIS
EP3946054A4 (en) COMPOSITIONS, METHODS AND SYSTEMS FOR PROTEIN CORONA ANALYSIS FROM BIOLIQUIDS AND THEIR USES
IL290257A (en) Systems and methods for sample preparation, data generation and corona protein analysis
IL290612A (en) Systems and methods for protein prediction
EP3464610A4 (en) PROTEIN COMPOSITION AND METHODS FOR MICROBIOTE ANALYSIS
EP3488018A4 (en) METHODS AND COMPOSITIONS FOR THE IDENTIFICATION OF PROTEINS
EP3612953A4 (en) CONTENT EVALUATION SYSTEMS AND METHODS
EP3847273A4 (en) SYSTEMS AND METHODS FOR MICROBIOMAN ANALYSIS
EP3298135A4 (en) SYSTEMS AND METHODS FOR PREDICTING GLYCOSYLATION ON PROTEINS
IL291284A (en) Systems and methods for expression of proteins
IL287458A (en) Methods and systems for microsatellite analysis
EP3631414A4 (en) ASSAY SYSTEMS AND METHODS FOR PROCESSING SAMPLE ENTITIES
EP3976825A4 (en) SYSTEMS AND METHODS FOR SEQUENCE DETERMINATION
EP3347477A4 (en) COMPOSITIONS AND METHODS FOR PROTEIN DETECTION