SG11202104497VA - Optimized process for dimeric peptide-phospholipid conjugate - Google Patents

Optimized process for dimeric peptide-phospholipid conjugate

Info

Publication number
SG11202104497VA
SG11202104497VA SG11202104497VA SG11202104497VA SG11202104497VA SG 11202104497V A SG11202104497V A SG 11202104497VA SG 11202104497V A SG11202104497V A SG 11202104497VA SG 11202104497V A SG11202104497V A SG 11202104497VA SG 11202104497V A SG11202104497V A SG 11202104497VA
Authority
SG
Singapore
Prior art keywords
optimized process
dimeric peptide
phospholipid conjugate
phospholipid
conjugate
Prior art date
Application number
SG11202104497VA
Other languages
English (en)
Inventor
Anthony Clouet
Bernard Lamy
Original Assignee
Bracco Suisse Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Suisse Sa filed Critical Bracco Suisse Sa
Publication of SG11202104497VA publication Critical patent/SG11202104497VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/543Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
    • A61K47/544Phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/20Partition-, reverse-phase or hydrophobic interaction chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acoustics & Sound (AREA)
  • Peptides Or Proteins (AREA)
  • Gastroenterology & Hepatology (AREA)
SG11202104497VA 2018-12-18 2019-12-16 Optimized process for dimeric peptide-phospholipid conjugate SG11202104497VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18213539 2018-12-18
PCT/EP2019/085459 WO2020127124A1 (fr) 2018-12-18 2019-12-16 Procédé optimisé pour conjugué peptide-phospholipide dimère

Publications (1)

Publication Number Publication Date
SG11202104497VA true SG11202104497VA (en) 2021-05-28

Family

ID=65009520

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104497VA SG11202104497VA (en) 2018-12-18 2019-12-16 Optimized process for dimeric peptide-phospholipid conjugate

Country Status (11)

Country Link
US (1) US11484596B2 (fr)
EP (1) EP3897736B1 (fr)
JP (1) JP7421554B2 (fr)
KR (1) KR20210106418A (fr)
CN (1) CN113164613B (fr)
BR (1) BR112021008753A2 (fr)
CA (1) CA3118523A1 (fr)
ES (1) ES2930177T3 (fr)
IL (1) IL284167A (fr)
SG (1) SG11202104497VA (fr)
WO (1) WO2020127124A1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7985402B2 (en) * 2002-03-01 2011-07-26 Bracco Suisse Sa Targeting vector-phospholipid conjugates
US7666979B2 (en) 2002-03-01 2010-02-23 Bracco International B.V. Methods for preparing multivalent constructs for therapeutic and diagnostic applications and methods of preparing the same
FI20050695A0 (fi) 2005-06-30 2005-06-30 Ctt Cancer Targeting Tech Oy Menetelmä fosfolipidi-PEG-biomolekyyli-konjugaattien valmistamiseksi
KR101323849B1 (ko) 2005-12-09 2013-11-07 브라코 스위스 에스.에이. 표적화 벡터-포스포리피드 컨쥬게이트
JP5364589B2 (ja) * 2006-12-11 2013-12-11 ブラッコ・イメージング・ソシエタ・ペル・アチオニ 診断および治療適用用フィブリン結合ペプチドコンジュゲート

Also Published As

Publication number Publication date
KR20210106418A (ko) 2021-08-30
WO2020127124A1 (fr) 2020-06-25
JP7421554B2 (ja) 2024-01-24
BR112021008753A2 (pt) 2021-08-10
US11484596B2 (en) 2022-11-01
US20220202944A1 (en) 2022-06-30
EP3897736A1 (fr) 2021-10-27
EP3897736B1 (fr) 2022-10-12
CN113164613A (zh) 2021-07-23
IL284167A (en) 2021-08-31
CA3118523A1 (fr) 2020-06-25
JP2022512406A (ja) 2022-02-03
CN113164613B (zh) 2024-06-07
ES2930177T3 (es) 2022-12-07

Similar Documents

Publication Publication Date Title
HUS2100025I1 (hu) Anti-HER2 antitest-hatóanyag konjugátum
SG11202000997YA (en) Improved method for producing antibody-drug conjugate
IL272964A (en) Production method for antibody-drug conjugates
IL273471B1 (en) Conjugation of an antibody with a pyrrolobenzodiazepine derivative
HK1247211A1 (zh) 用於選擇性製造抗體-藥物綴合物的方法
IL272384B (en) A process for the preparation of pyrrolidine compounds
EP3603663A4 (fr) Procédé de préparation de conjugué anticorps-médicament
GB201719867D0 (en) Apparatus for heating aerosolisable
IL274439A (en) Process for making Tapinaroff
SG11202005466VA (en) Timing considerations for aul-dfi
SG11202104993SA (en) Anti-cdh6 antibody-pyrrolobenzodiazepine derivative conjugate
IL260465B (en) A process for preparing an antibody-rifamycin conjugate
IL283331A (en) Method for the preparation of n-phenylpyrazole-1-carboxamides
GB2598463B (en) Improved methods for angiography
KR102342082B9 (ko) 양액미립자층을 구비하는 식물 재배 수단
HUE056722T2 (hu) Javított eljárás imetelstat elõállítására
IL282108A (en) A method for preparing epiconazole
IL284167A (en) Optimal process for peptide - phospholipid conjugation
GB202112727D0 (en) Application for letters patent
PT3643208T (pt) Estante de armazenamento para garrafas
SG10202112966SA (en) Process for preparing αlpha-carboxamide pyrrolidine derivatives
IL269414A (en) Rapar for safetyin taneis
IL286006A (en) Process for preparing 4-amino-5-methylpyridone
GB201917804D0 (en) Conjugate
GB201802269D0 (en) Handbarrow for carrying patients