SG11202104432YA - Cxcl8 binding nucleic acids - Google Patents

Cxcl8 binding nucleic acids

Info

Publication number
SG11202104432YA
SG11202104432YA SG11202104432YA SG11202104432YA SG11202104432YA SG 11202104432Y A SG11202104432Y A SG 11202104432YA SG 11202104432Y A SG11202104432Y A SG 11202104432YA SG 11202104432Y A SG11202104432Y A SG 11202104432YA SG 11202104432Y A SG11202104432Y A SG 11202104432YA
Authority
SG
Singapore
Prior art keywords
nucleic acids
binding nucleic
cxcl8 binding
cxcl8
acids
Prior art date
Application number
SG11202104432YA
Other languages
English (en)
Inventor
Kai Höhlig
Axel Vater
Werner Purschke
Dirk Zboralski
Christian Maasch
Original Assignee
Aptarion Biotech Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aptarion Biotech Ag filed Critical Aptarion Biotech Ag
Publication of SG11202104432YA publication Critical patent/SG11202104432YA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/32—Chemical structure of the sugar
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/351—Conjugate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/35—Nature of the modification
    • C12N2310/351—Conjugate
    • C12N2310/3515—Lipophilic moiety, e.g. cholesterol
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/5421—IL-8

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Urology & Nephrology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • General Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SG11202104432YA 2018-11-12 2019-11-12 Cxcl8 binding nucleic acids SG11202104432YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18205750 2018-11-12
PCT/EP2019/000312 WO2020098968A1 (en) 2018-11-12 2019-11-12 Cxcl8 binding nucleic acids

Publications (1)

Publication Number Publication Date
SG11202104432YA true SG11202104432YA (en) 2021-05-28

Family

ID=64308548

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202104432YA SG11202104432YA (en) 2018-11-12 2019-11-12 Cxcl8 binding nucleic acids

Country Status (12)

Country Link
US (1) US20210403913A1 (ko)
EP (1) EP3880822A1 (ko)
JP (1) JP2022512969A (ko)
KR (1) KR20210113173A (ko)
CN (1) CN113383079A (ko)
AU (1) AU2019378732A1 (ko)
BR (1) BR112021007724A2 (ko)
CA (1) CA3119357A1 (ko)
IL (1) IL282494A (ko)
MX (1) MX2021005525A (ko)
SG (1) SG11202104432YA (ko)
WO (1) WO2020098968A1 (ko)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59708838D1 (de) * 1996-08-30 2003-01-09 Jens Peter Fuerste Spiegelselektion und spiegelevolution von nucleinsäuren
SG11201403771SA (en) * 2012-01-10 2014-07-30 Noxxon Pharma Ag New c5a binding nucleic acids
US9163243B2 (en) * 2012-01-10 2015-10-20 Noxxon Pharma Ag Nucleic acids specifically binding CGRP
KR101458947B1 (ko) * 2013-03-05 2014-11-12 국립암센터 인터루킨-８ 앱타머 및 이의 용도
WO2015169811A2 (en) * 2014-05-06 2015-11-12 Medimmune Limited Anti-cxc chemokine receptor-2 binding molecules and uses thereof
FI20165814A (fi) * 2016-10-27 2018-04-28 Tilt Biotherapeutics Oy Interleukiini 8 (il-8) prognostisena ja ennustavana biomarkkerina ja koostumukset ja vektorit käytettäväksi onkolyyttisessa immunoterapiassa
US11739335B2 (en) * 2017-03-24 2023-08-29 CureVac SE Nucleic acids encoding CRISPR-associated proteins and uses thereof

Also Published As

Publication number Publication date
JP2022512969A (ja) 2022-02-07
CA3119357A1 (en) 2020-05-22
BR112021007724A2 (pt) 2021-08-10
WO2020098968A8 (en) 2021-06-10
EP3880822A1 (en) 2021-09-22
MX2021005525A (es) 2021-06-18
WO2020098968A1 (en) 2020-05-22
KR20210113173A (ko) 2021-09-15
US20210403913A1 (en) 2021-12-30
CN113383079A (zh) 2021-09-10
IL282494A (en) 2021-06-30
AU2019378732A1 (en) 2021-05-27

Similar Documents

Publication Publication Date Title
IL271342A (en) Nucleases are guided by nucleic acids
GB201804860D0 (en) CD47 Binding agents
IL274926A (en) Pyrazolopyrimidines with activity against respiratory syncytial virus
ZA201804317B (en) Altered april binding antibodies
IL277472A (en) Nucleic acid molecules for pseudouridylation
GB201907242D0 (en) Dna methods etc ii
IL280528A (en) A method for the evaluation of integrated nucleic acids
GB201812474D0 (en) Nucleic acid construct
IL304317A (en) tgf–beta–rii binding proteins
ZA201906821B (en) Anti-jagged1 antigen binding proteins
IL269608A (en) P-ETHOXY nucleic acids for inhibition of STAT3
IL284317A (en) FAB pseudoproteins are multispecific binding proteins
EP4076343C0 (en) RETINOL BASED SERUM
IL267318A (en) link test
EP3766972A4 (en) NUCLEIC ACID COMPLEX
EP3633037A4 (en) NUCLEIC ACIDS SUPPRESSING APCS EXPRESSION
IL282494A (en) Nucleic acids bind CXCL8
GB201614627D0 (en) Antigen binding proteins
GB201609115D0 (en) Isolating nucleic acids
EP3894580C0 (en) FAMIN ASSAY METHODS
GB201706802D0 (en) Base-modified nucleic acids
GB201706801D0 (en) Base-modified nucleic acids
GB201808882D0 (en) Nucleic acids and uses thereof
GB201919286D0 (en) Binding proteins
GB201815836D0 (en) Nucleic acid conjugates