SG11202104192TA - Combination of small molecule cd-47 inhibitors with other anti-cancer agents - Google Patents
Combination of small molecule cd-47 inhibitors with other anti-cancer agentsInfo
- Publication number
- SG11202104192TA SG11202104192TA SG11202104192TA SG11202104192TA SG11202104192TA SG 11202104192T A SG11202104192T A SG 11202104192TA SG 11202104192T A SG11202104192T A SG 11202104192TA SG 11202104192T A SG11202104192T A SG 11202104192TA SG 11202104192T A SG11202104192T A SG 11202104192TA
- Authority
- SG
- Singapore
- Prior art keywords
- inhibitors
- combination
- small molecule
- cancer agents
- cancer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201841042108 | 2018-11-08 | ||
| PCT/IB2019/059602 WO2020095256A1 (en) | 2018-11-08 | 2019-11-08 | Combination of small molecule cd-47 inhibitors with other anti-cancer agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202104192TA true SG11202104192TA (en) | 2021-05-28 |
Family
ID=69159806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202104192TA SG11202104192TA (en) | 2018-11-08 | 2019-11-08 | Combination of small molecule cd-47 inhibitors with other anti-cancer agents |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US11311517B2 (es) |
| EP (1) | EP3876931A1 (es) |
| JP (1) | JP2022507025A (es) |
| KR (1) | KR20210088584A (es) |
| CN (1) | CN112930181A (es) |
| AU (1) | AU2019375193A1 (es) |
| BR (1) | BR112021008781A2 (es) |
| CA (1) | CA3118843A1 (es) |
| EA (1) | EA202190776A1 (es) |
| IL (1) | IL282972A (es) |
| MX (1) | MX2021005240A (es) |
| PH (1) | PH12021550832A1 (es) |
| SG (1) | SG11202104192TA (es) |
| WO (1) | WO2020095256A1 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2019138367A1 (en) * | 2018-01-12 | 2019-07-18 | Aurigene Discovery Technologies Limited | 1,2,4-oxadiazole compounds as inhibitors of cd47 signalling pathways |
| JP2024508395A (ja) * | 2021-02-10 | 2024-02-27 | グレート ノベル セラピューティクス バイオテック アンド メディカルズ コーポレイション | がんに対する免疫応答を刺激する又は免疫抑制を克服するための医薬組み合わせ及び方法 |
| CN113018415B (zh) * | 2021-03-17 | 2022-07-01 | 遵义医科大学 | 一种药物组合及其应用 |
| CN113750215B (zh) * | 2021-09-24 | 2023-06-23 | 暨南大学 | 用于治疗肿瘤的联合药物 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6521977B2 (ja) | 2013-09-06 | 2019-05-29 | オーリジーン ディスカバリー テクノロジーズ リミテッドＡｕｒｉｇｅｎｅ Ｄｉｓｃｏｖｅｒｙ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｉｍｉｔｅｄ | 免疫調節剤としての１，２，４−オキサジアゾール誘導体 |
| EP3267984B1 (en) * | 2015-03-10 | 2021-11-24 | Aurigene Discovery Technologies Limited | 1,2,4-oxadiazole and thiadiazole compounds as immunomodulators |
| EP3267985A4 (en) | 2015-03-10 | 2018-07-25 | Aurigene Discovery Technologies Limited | 3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators |
| US20160304809A1 (en) | 2015-04-14 | 2016-10-20 | The Procter & Gamble Company | Consumer Product Composition |
| CN104804093A (zh) | 2015-05-27 | 2015-07-29 | 江苏春申堂药业有限公司 | 一种针对cd47的单域抗体 |
| GB2558131B (en) | 2015-09-21 | 2021-05-19 | Surface Oncology Inc | Anti-CD47 antibodies and methods of use |
| EP3243522A1 (en) | 2016-05-10 | 2017-11-15 | Université Pierre et Marie Curie (Paris 6) | Agonist agents of cd47 inducing programmed cell death and their use in the treatments of diseases associated with defects in programmed cell death |
| ES2908729T3 (es) | 2016-05-10 | 2022-05-03 | Inst Nat Sante Rech Med | Nuevos compuestos y uso farmacéutico de los mismos en el tratamiento del cáncer |
| WO2018047139A1 (en) * | 2016-09-12 | 2018-03-15 | Aurigene Discovery Technologies Limited | Compounds as modulators of tigit signalling pathway |
| EP3529235A4 (en) * | 2016-10-20 | 2020-07-08 | Aurigene Discovery Technologies Limited | DOUBLE VISTA AND PD -1 CHANNEL INHIBITORS |
| WO2019138367A1 (en) * | 2018-01-12 | 2019-07-18 | Aurigene Discovery Technologies Limited | 1,2,4-oxadiazole compounds as inhibitors of cd47 signalling pathways |
| CN118236374A (zh) * | 2018-03-14 | 2024-06-25 | 奥瑞基尼肿瘤有限公司 | 使用1,2,4-噁二唑化合物调节tigit和pd-1信号传导途径的方法 |
-
2019
- 2019-11-08 MX MX2021005240A patent/MX2021005240A/es unknown
- 2019-11-08 CA CA3118843A patent/CA3118843A1/en active Pending
- 2019-11-08 US US16/678,594 patent/US11311517B2/en active Active
- 2019-11-08 WO PCT/IB2019/059602 patent/WO2020095256A1/en unknown
- 2019-11-08 AU AU2019375193A patent/AU2019375193A1/en active Pending
- 2019-11-08 KR KR1020217014395A patent/KR20210088584A/ko active Search and Examination
- 2019-11-08 EA EA202190776A patent/EA202190776A1/ru unknown
- 2019-11-08 BR BR112021008781-8A patent/BR112021008781A2/pt unknown
- 2019-11-08 EP EP19835717.0A patent/EP3876931A1/en active Pending
- 2019-11-08 JP JP2021524166A patent/JP2022507025A/ja active Pending
- 2019-11-08 SG SG11202104192TA patent/SG11202104192TA/en unknown
- 2019-11-08 CN CN201980071532.5A patent/CN112930181A/zh active Pending
-
2021
- 2021-04-13 PH PH12021550832A patent/PH12021550832A1/en unknown
- 2021-05-05 IL IL282972A patent/IL282972A/en unknown
-
2022
- 2022-04-25 US US17/728,325 patent/US20220241248A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20220241248A1 (en) | 2022-08-04 |
| WO2020095256A1 (en) | 2020-05-14 |
| US11311517B2 (en) | 2022-04-26 |
| US20200147054A1 (en) | 2020-05-14 |
| JP2022507025A (ja) | 2022-01-18 |
| BR112021008781A2 (pt) | 2021-08-03 |
| CN112930181A (zh) | 2021-06-08 |
| PH12021550832A1 (en) | 2021-10-04 |
| IL282972A (en) | 2021-06-30 |
| EA202190776A1 (ru) | 2021-09-20 |
| CA3118843A1 (en) | 2020-05-14 |
| MX2021005240A (es) | 2021-06-18 |
| EP3876931A1 (en) | 2021-09-15 |
| AU2019375193A1 (en) | 2021-05-13 |
| KR20210088584A (ko) | 2021-07-14 |
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