SG11202010395XA - Electroporation systems, methods, and apparatus - Google Patents

Electroporation systems, methods, and apparatus

Info

Publication number
SG11202010395XA
SG11202010395XA SG11202010395XA SG11202010395XA SG11202010395XA SG 11202010395X A SG11202010395X A SG 11202010395XA SG 11202010395X A SG11202010395X A SG 11202010395XA SG 11202010395X A SG11202010395X A SG 11202010395XA SG 11202010395X A SG11202010395X A SG 11202010395XA
Authority
SG
Singapore
Prior art keywords
methods
electroporation systems
electroporation
systems
Prior art date
Application number
SG11202010395XA
Other languages
English (en)
Inventor
John F Rodriguez
Brandon Dang Phung
Christopher G Twitty
Jason Jin
Original Assignee
Oncosec Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncosec Medical Inc filed Critical Oncosec Medical Inc
Publication of SG11202010395XA publication Critical patent/SG11202010395XA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3476—Powered trocars, e.g. electrosurgical cutting, lasers, powered knives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3478—Endoscopic needles, e.g. for infusion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206—Generators therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/30—Surgical robots
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/208—IL-12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0472—Structure-related aspects
    • A61N1/0476—Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0507—Electrodes for the digestive system
    • A61N1/0509—Stomach and intestinal electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00166—Multiple lumina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00541—Lung or bronchi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00613—Irreversible electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00642—Sensing and controlling the application of energy with feedback, i.e. closed loop control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00696—Controlled or regulated parameters
    • A61B2018/00702—Power or energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00875—Resistance or impedance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A61B2018/143—Needle multiple needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/05—General characteristics of the apparatus combined with other kinds of therapy
    • A61M2205/054—General characteristics of the apparatus combined with other kinds of therapy with electrotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Robotics (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Surgical Instruments (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11202010395XA 2018-05-02 2019-05-02 Electroporation systems, methods, and apparatus SG11202010395XA (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201862665553P 2018-05-02 2018-05-02
US201862742684P 2018-10-08 2018-10-08
US201862745699P 2018-10-15 2018-10-15
US201862755001P 2018-11-02 2018-11-02
US201962824011P 2019-03-26 2019-03-26
PCT/US2019/030437 WO2019213421A1 (en) 2018-05-02 2019-05-02 Electroporation systems, methods, and apparatus

Publications (1)

Publication Number Publication Date
SG11202010395XA true SG11202010395XA (en) 2020-11-27

Family

ID=68384469

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202010395XA SG11202010395XA (en) 2018-05-02 2019-05-02 Electroporation systems, methods, and apparatus

Country Status (12)

Country Link
US (2) US20190336757A1 (https=)
EP (1) EP3787665A4 (https=)
JP (1) JP2021523763A (https=)
KR (1) KR102793500B1 (https=)
CN (1) CN112236192B (https=)
AU (1) AU2019263465A1 (https=)
BR (1) BR112020021981A2 (https=)
CA (1) CA3098615A1 (https=)
IL (1) IL278210A (https=)
MX (1) MX2020011618A (https=)
SG (1) SG11202010395XA (https=)
WO (1) WO2019213421A1 (https=)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8903488B2 (en) 2009-05-28 2014-12-02 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9078665B2 (en) 2011-09-28 2015-07-14 Angiodynamics, Inc. Multiple treatment zone ablation probe
ES2807439T3 (es) 2015-03-31 2021-02-23 Oncosec Medical Inc Sistemas para electroporación mejorada basada en la detección de tejidos
TWI850282B (zh) 2018-11-27 2024-08-01 香港商弘年發展有限公司 用於治療癌症之質體建構體和使用方法
US11071860B2 (en) * 2019-02-06 2021-07-27 Oncosec Medical Incorporated Systems and methods for detecting fault conditions in electroporation therapy
US11250780B2 (en) 2019-08-15 2022-02-15 Samsung Display Co., Ltd. Estimation of pixel compensation coefficients by adaptation
US11087656B2 (en) * 2019-08-15 2021-08-10 Samsung Display Co., Ltd. Fully differential front end for sensing
US11069282B2 (en) 2019-08-15 2021-07-20 Samsung Display Co., Ltd. Correlated double sampling pixel sensing front end
US11081064B1 (en) 2020-01-13 2021-08-03 Samsung Display Co., Ltd. Reference signal generation by reusing the driver circuit
WO2021158685A1 (en) * 2020-02-04 2021-08-12 Oncosec Medical Incorporated Hemostatic combination therapy with low voltage electroporation
US11257416B2 (en) 2020-02-14 2022-02-22 Samsung Display Co., Ltd. Voltage mode pre-emphasis with floating phase
US20210290941A1 (en) * 2020-03-20 2021-09-23 Inovio Pharmaceuticals Inc Vacuum-Assisted Electroporation Devices, And Related Systems And Methods
US20220249151A1 (en) * 2020-04-13 2022-08-11 Angiodynamics, Inc. Treatment planning and monitoring for ire and h-fire protocols
EP4167889A4 (en) * 2020-06-19 2024-12-04 Grand Decade Developments Limited METHODS FOR DETERMINING RESPONSIVENESS TO CANCER IMMUNOTHERAPY
WO2021262989A1 (en) * 2020-06-24 2021-12-30 Oncosec Medical Incorporated Transformable needle for electroporation
KR102490645B1 (ko) * 2020-07-16 2023-01-25 고려대학교 산학협력단 흡수에너지 기반 전기장 암치료 계획 시스템 및 방법
IL300106A (en) * 2020-07-29 2023-03-01 Oncosec Medical Inc Combination therapy for cancer treatment
WO2022038535A1 (en) * 2020-08-20 2022-02-24 Cochlear Limited Electroporation shield for implantable electrodes
WO2022072385A2 (en) * 2020-09-30 2022-04-07 Boston Scientific Scimed Inc Pretreatment waveform for irreversible electroporation
US11719738B2 (en) 2020-10-15 2023-08-08 Samsung Display Co., Ltd. Two-domain two-stage sensing front-end circuits and systems
KR102277440B1 (ko) 2020-12-07 2021-07-14 (주)더스탠다드 감자 모델에서 ttc를 이용하는 전기 천공 영역 검출 방법
WO2022137171A2 (en) * 2020-12-24 2022-06-30 Novocure Gmbh Methods and compositions for using alternating electric fields in gene therapy
US12446944B2 (en) 2021-04-26 2025-10-21 Pulse Biosciences, Inc. Mapping and ablation applicators
US12564440B2 (en) 2021-04-26 2026-03-03 Pulse Biosciences, Inc. Multi-strut ablation and sensing catheter devices and methods
AU2022263951B2 (en) 2021-04-26 2024-12-05 Pulse Biosciences, Inc. Circumferential ablation devices and methods
US20220370128A1 (en) 2021-05-18 2022-11-24 Biosense Webster (Israel) Ltd. Efficiency of ire ablation procedure by applying stress signal to target tissue
KR102326448B1 (ko) * 2021-06-29 2021-11-15 (주)더스탠다드 안정적으로 출력 고전압을 모니터링하는 비가역적 전기천공 시스템
WO2023277488A1 (ko) * 2021-06-29 2023-01-05 (주)더스탠다드 비가역적 전기천공 시스템 및 그것의 펄스 인가 방법
US20240366290A1 (en) * 2021-09-15 2024-11-07 Focal Medical Technology Ltd Tissue ablation guided by electrical impedance spectroscopy
WO2023064934A1 (en) * 2021-10-15 2023-04-20 Intergalactic Therapeutics, Inc. Respiratory delivery of therapeutic agents
KR102410404B1 (ko) 2021-12-17 2022-06-22 (주)딥인사이트 언더 디스플레이 카메라를 이용하는 스마트 거울
CN115050254B (zh) * 2022-07-11 2023-10-13 暨南大学附属第一医院（广州华侨医院） 一种微创清除拉克氏囊肿用手术练习模型
CN114983551B (zh) * 2022-07-12 2022-10-25 深圳迈微医疗科技有限公司 组织消融装置以及电化学阻抗测量装置
IT202200019635A1 (it) 2022-09-23 2024-03-23 Igea S P A Dispositivo per l'elettroporazione migliorato
CN117883273A (zh) * 2022-10-08 2024-04-16 深圳市威尔达塑胶五金制品有限公司 一种洗鼻器
WO2024160853A1 (en) * 2023-01-31 2024-08-08 Eth Zurich Pulsed electric fields in 3d histology
WO2025054502A1 (en) * 2023-09-06 2025-03-13 Shifamed Holdings, Llc Methods for creating and maintaining blebs via electroporation and associated systems and devices
WO2025166244A2 (en) * 2024-01-31 2025-08-07 The Johns Hopkins University Albumin-fused flt3l nucleic acid compositions and methods
KR102680155B1 (ko) * 2024-05-02 2024-07-03 (주)더스탠다드 간격 조절 장치
GB202411573D0 (en) * 2024-08-06 2024-09-18 Creo Medical Ltd Electrosurgical instrument
CN119112346B (zh) * 2024-11-12 2025-03-07 北京理工大学 一种电穿孔器件及其应用
CN120643299A (zh) * 2025-06-30 2025-09-16 杭州康生医疗器械有限公司 一种手术电极及其使用方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5704908A (en) * 1996-10-10 1998-01-06 Genetronics, Inc. Electroporation and iontophoresis catheter with porous balloon
US5873877A (en) * 1997-04-11 1999-02-23 Vidamed, Inc. Medical probe device with transparent distal extremity
US6241701B1 (en) 1997-08-01 2001-06-05 Genetronics, Inc. Apparatus for electroporation mediated delivery of drugs and genes
US6055453A (en) 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
US7456012B2 (en) * 1997-11-06 2008-11-25 Cellectricon Ab Method and apparatus for spatially confined electroporation
US20040204669A1 (en) * 2001-07-05 2004-10-14 Hofmann Gunter A. Apparatus for electroporation mediated delivery for drugs and genes
US6912417B1 (en) * 2002-04-05 2005-06-28 Ichor Medical Systmes, Inc. Method and apparatus for delivery of therapeutic agents
JP2004041434A (ja) * 2002-07-11 2004-02-12 Kiyohito Ishida エレクトロポレーション装置
US20060264752A1 (en) * 2005-04-27 2006-11-23 The Regents Of The University Of California Electroporation controlled with real time imaging
US20100298761A1 (en) * 2009-05-20 2010-11-25 Sonion A/S Electroporation device with improved tip and electrode support
ES2956272T3 (es) * 2009-08-31 2023-12-18 Applied Med Resources Sistema de acceso quirúrgico multifuncional
BR112012029263B8 (pt) * 2010-05-21 2022-08-16 Nimbus Concepts Llc Agulha de neurotomia por radiofrequência
WO2014207077A1 (en) * 2013-06-26 2014-12-31 Atropos Limited An inflatable pneumoperitoneum device
WO2014066655A2 (en) 2012-10-25 2014-05-01 Oncosec Medical Incorporation Electroporation device
EP2941299B1 (en) * 2012-12-21 2018-10-17 University College Cork-National University of Ireland, Cork A thoracoscopic electroporation device with a suction head and with needle electrodes
US9536205B2 (en) * 2013-01-24 2017-01-03 Nec Corporation Adaptive control of hybrid ultracapacitor-battery storage system for photovoltaic output smoothing
US10368850B2 (en) * 2014-06-18 2019-08-06 Siemens Medical Solutions Usa, Inc. System and method for real-time ultrasound guided prostate needle biopsies using a compliant robotic arm
ES2881213T3 (es) * 2014-11-13 2021-11-29 Applied Med Resources Sistemas para la extracción de tejido
PL3242947T3 (pl) * 2015-01-09 2021-01-11 Oncosec Medical Incorporated Terapia genowa i elektroporacja do leczenia zmian złośliwych
CA2975931A1 (en) * 2015-02-04 2016-08-11 Rfemb Holdings, Llc Radio-frequency electrical membrane breakdown for the treatment of adipose tissue and removal of unwanted body fat
US20180044429A1 (en) * 2015-03-09 2018-02-15 Celldex Therapeutics, Inc. Cd27 agonists
ES2807439T3 (es) * 2015-03-31 2021-02-23 Oncosec Medical Inc Sistemas para electroporación mejorada basada en la detección de tejidos
AU2017331275A1 (en) * 2016-09-23 2019-05-16 Oncosec Medical Incorporated Modulating responses to checkpoint inhibitor therapy

Also Published As

Publication number Publication date
AU2019263465A1 (en) 2020-12-24
JP2021523763A (ja) 2021-09-09
US20200316376A1 (en) 2020-10-08
CA3098615A1 (en) 2019-11-07
KR20210018228A (ko) 2021-02-17
BR112020021981A2 (pt) 2021-01-26
WO2019213421A1 (en) 2019-11-07
EP3787665A4 (en) 2022-02-16
CN112236192B (zh) 2024-09-03
US20190336757A1 (en) 2019-11-07
IL278210A (en) 2020-11-30
KR102793500B1 (ko) 2025-04-14
MX2020011618A (es) 2021-02-16
CN112236192A (zh) 2021-01-15
EP3787665A1 (en) 2021-03-10

Similar Documents

Publication Publication Date Title
IL278210A (en) Electroporation systems, methods and devices
GB2596950B (en) Methods, apparatus and systems for biometric processes
SG11202009776QA (en) Communication method, apparatus, and system
GB201801530D0 (en) Methods, apparatus and systems for authentication
GB201801526D0 (en) Methods, apparatus and systems for authentication
GB201803113D0 (en) Device, system and method
GB2594423B (en) System, apparatus and method
PT3640936T (pt) Dispositivo de controlo de aparelho, método, e aparelho tendo o mesmo
PL3573392T3 (pl) Sposób, urządzenie i system komunikacji
SG11202104125TA (en) Apparatus, systems, and methods for stemmed blockchain operation
SG10202107782UA (en) Device configuration method, apparatus and system
GB201608270D0 (en) Method, system and apparatus
GB201703379D0 (en) Drinking apparatus, system and associated methods
GB201817602D0 (en) Injection apparatus, method and system
GB2578589B (en) Head-mountable apparatus, systems and methods
GB201701753D0 (en) System, apparatus and method
GB201807821D0 (en) System, device, apparatus and method
GB201717345D0 (en) Peptides, methods and apparatus
GB201622227D0 (en) Communication apparatus, methods and system
SG11202006391WA (en) Verification-processing device, logic-generating device, and verification-processing method
GB201712570D0 (en) Communication apparatus, method and system
ZA201904163B (en) Communication method, apparatus and system
HK40048025A (en) Electroporation systems, methods, and apparatus
GB201819712D0 (en) Biometric systems, apparatus and methods
GB201807036D0 (en) Communication systems, apparatus and methods