SG11202008543RA - Pyrrolidineamide derivatives and uses thereof - Google Patents
Pyrrolidineamide derivatives and uses thereofInfo
- Publication number
- SG11202008543RA SG11202008543RA SG11202008543RA SG11202008543RA SG11202008543RA SG 11202008543R A SG11202008543R A SG 11202008543RA SG 11202008543R A SG11202008543R A SG 11202008543RA SG 11202008543R A SG11202008543R A SG 11202008543RA SG 11202008543R A SG11202008543R A SG 11202008543RA
- Authority
- SG
- Singapore
- Prior art keywords
- pyrrolidineamide
- derivatives
- pyrrolidineamide derivatives
- Prior art date
Links
- LCDCPQHFCOBUEF-UHFFFAOYSA-N pyrrolidine-1-carboxamide Chemical class NC(=O)N1CCCC1 LCDCPQHFCOBUEF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Vascular Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810192198 | 2018-03-08 | ||
| PCT/CN2019/077249 WO2019170115A1 (en) | 2018-03-08 | 2019-03-07 | Pyrrolidineamide derivatives and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11202008543RA true SG11202008543RA (en) | 2020-10-29 |
Family
ID=67845842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11202008543RA SG11202008543RA (en) | 2018-03-08 | 2019-03-07 | Pyrrolidineamide derivatives and uses thereof |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11225460B2 (https=) |
| EP (1) | EP3762364B1 (https=) |
| JP (1) | JP7405756B2 (https=) |
| CN (1) | CN110240557B (https=) |
| AU (1) | AU2019230883B2 (https=) |
| CA (1) | CA3092747A1 (https=) |
| SG (1) | SG11202008543RA (https=) |
| WO (1) | WO2019170115A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240317681A1 (en) * | 2020-07-07 | 2024-09-26 | Sunshine Lake Pharma Co., Ltd. | Pyrrolidine amide derivative salt and use thereof |
| CN113896671B (zh) * | 2020-07-07 | 2023-06-09 | 广东东阳光药业有限公司 | 吡咯烷酰胺衍生物的盐及其用途 |
| CN113896670B (zh) * | 2020-07-07 | 2023-06-09 | 广东东阳光药业有限公司 | 吡咯烷酰胺衍生物的盐及其用途 |
| CN114573491B (zh) * | 2020-12-01 | 2023-12-08 | 广东东阳光药业股份有限公司 | 吡咯烷酰胺衍生物的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL94466A (en) | 1989-05-25 | 1995-01-24 | Erba Carlo Spa | Pharmaceutical preparations containing the history of A-amino carboxamide N-phenylalkyl are converted into such new compounds and their preparation |
| WO2000033788A2 (en) | 1998-12-11 | 2000-06-15 | American Biogenetic Sciences Inc. | Substituted nitrogen heterocyclic compounds and therapeutic uses thereof |
| FR2799461B1 (fr) | 1999-10-11 | 2002-01-04 | Sod Conseils Rech Applic | Derives d'heterocycles a 5 chainons, leur preparation et leur application a titre de medicaments |
| MY134480A (en) * | 2002-09-20 | 2007-12-31 | Hoffmann La Roche | 4-pyrrolidino-phenyl-benzyl ether derivatives |
| EP1524265A1 (en) * | 2003-10-15 | 2005-04-20 | Newron Pharmaceuticals S.p.A. | Prolinamide derivatives as sodium and/or calcium channel blockers or selective MAO-B inhibitors |
| WO2006013049A2 (en) * | 2004-08-02 | 2006-02-09 | F.Hoffmann-La Roche Ag | Benzyloxy derivatives as maob inhibitors |
| US7501528B2 (en) | 2005-03-15 | 2009-03-10 | Hoffmann-La Roche Inc. | Method for preparing enantiomerically pure 4-pyrrolidino phenylbenzyl ether derivatives |
| US20070078172A1 (en) | 2005-06-16 | 2007-04-05 | Jenrin Discovery | Mao-b inhibitors useful for treating obesity |
| BRPI0821026A2 (pt) | 2007-12-19 | 2015-06-16 | Newron Pharmaceutical S P A | Derivados de alfa-minoamidas úteis no tratamento de transtornos psiquiátricos |
| CA2886904A1 (en) * | 2012-10-02 | 2014-04-10 | Cyril Montagne | Pyrrolidines |
| EP3601255A1 (en) | 2017-03-21 | 2020-02-05 | AbbVie Deutschland GmbH & Co. KG | Proline amide compounds and their azetidine analogues carrying a specifically substituted benzyl radical |
-
2019
- 2019-03-07 EP EP19764310.9A patent/EP3762364B1/en active Active
- 2019-03-07 JP JP2020546886A patent/JP7405756B2/ja active Active
- 2019-03-07 US US16/977,487 patent/US11225460B2/en active Active
- 2019-03-07 AU AU2019230883A patent/AU2019230883B2/en active Active
- 2019-03-07 SG SG11202008543RA patent/SG11202008543RA/en unknown
- 2019-03-07 CA CA3092747A patent/CA3092747A1/en active Pending
- 2019-03-07 WO PCT/CN2019/077249 patent/WO2019170115A1/en not_active Ceased
- 2019-03-07 CN CN201910170019.3A patent/CN110240557B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN110240557A (zh) | 2019-09-17 |
| WO2019170115A1 (en) | 2019-09-12 |
| CN110240557B (zh) | 2023-05-09 |
| AU2019230883A1 (en) | 2020-09-24 |
| EP3762364A1 (en) | 2021-01-13 |
| JP7405756B2 (ja) | 2023-12-26 |
| US20210053918A1 (en) | 2021-02-25 |
| AU2019230883B2 (en) | 2024-02-01 |
| JP2021515019A (ja) | 2021-06-17 |
| EP3762364B1 (en) | 2023-08-23 |
| US11225460B2 (en) | 2022-01-18 |
| CA3092747A1 (en) | 2019-09-12 |
| EP3762364A4 (en) | 2021-08-04 |
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