SG11202008271QA - Progastrin as a biomarker for immunotherapy - Google Patents
Progastrin as a biomarker for immunotherapyInfo
- Publication number
- SG11202008271QA SG11202008271QA SG11202008271QA SG11202008271QA SG11202008271QA SG 11202008271Q A SG11202008271Q A SG 11202008271QA SG 11202008271Q A SG11202008271Q A SG 11202008271QA SG 11202008271Q A SG11202008271Q A SG 11202008271QA SG 11202008271Q A SG11202008271Q A SG 11202008271QA
- Authority
- SG
- Singapore
- Prior art keywords
- progastrin
- biomarker
- immunotherapy
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/595—Gastrins; Cholecystokinins [CCK]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/595—Gastrins; Cholecystokinins [CCK]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Food Science & Technology (AREA)
- Endocrinology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862635620P | 2018-02-27 | 2018-02-27 | |
PCT/EP2019/054878 WO2019166499A1 (en) | 2018-02-27 | 2019-02-27 | Progastrin as a biomarker for immunotherapy |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202008271QA true SG11202008271QA (en) | 2020-09-29 |
Family
ID=65685323
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202008271QA SG11202008271QA (en) | 2018-02-27 | 2019-02-27 | Progastrin as a biomarker for immunotherapy |
Country Status (10)
Country | Link |
---|---|
US (1) | US20200400675A1 (ko) |
EP (1) | EP3759492A1 (ko) |
JP (1) | JP7485274B2 (ko) |
KR (1) | KR20200144541A (ko) |
CN (1) | CN112368579B (ko) |
AU (1) | AU2019228339A1 (ko) |
CA (1) | CA3092414A1 (ko) |
SG (1) | SG11202008271QA (ko) |
TW (1) | TW202000699A (ko) |
WO (1) | WO2019166499A1 (ko) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019110662A1 (en) * | 2017-12-05 | 2019-06-13 | Progastrine Et Cancers S.À R.L. | Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer |
KR20240025729A (ko) | 2022-08-19 | 2024-02-27 | 울산대학교 산학협력단 | 특발성 폐섬유증 환자의 진단 및 예후예측용 신규 바이오마커 VISTA (V-domain immunoglobulin suppressor of T-cell activation) |
Family Cites Families (47)
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US4444887A (en) | 1979-12-10 | 1984-04-24 | Sloan-Kettering Institute | Process for making human antibody producing B-lymphocytes |
US4716111A (en) | 1982-08-11 | 1987-12-29 | Trustees Of Boston University | Process for producing human antibodies |
US4737456A (en) | 1985-05-09 | 1988-04-12 | Syntex (U.S.A.) Inc. | Reducing interference in ligand-receptor binding assays |
US6548640B1 (en) | 1986-03-27 | 2003-04-15 | Btg International Limited | Altered antibodies |
GB8720833D0 (en) | 1987-09-04 | 1987-10-14 | Celltech Ltd | Recombinant dna product |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
GB8924581D0 (en) | 1989-11-01 | 1989-12-20 | Pa Consulting Services | Bleaching of hair |
DK0710719T3 (da) | 1990-01-12 | 2007-07-09 | Amgen Fremont Inc | Frembringelse af xenogene antistoffer |
GB9014932D0 (en) | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
EP0519596B1 (en) | 1991-05-17 | 2005-02-23 | Merck & Co. Inc. | A method for reducing the immunogenicity of antibody variable domains |
WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
US5565332A (en) | 1991-09-23 | 1996-10-15 | Medical Research Council | Production of chimeric antibodies - a combinatorial approach |
JPH05244982A (ja) | 1991-12-06 | 1993-09-24 | Sumitomo Chem Co Ltd | 擬人化b−b10 |
US5474896A (en) | 1992-05-05 | 1995-12-12 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
US5792632A (en) | 1992-05-05 | 1998-08-11 | Institut Pasteur | Nucleotide sequence encoding the enzyme I-SceI and the uses thereof |
US5639641A (en) | 1992-09-09 | 1997-06-17 | Immunogen Inc. | Resurfacing of rodent antibodies |
ATE390933T1 (de) | 1995-04-27 | 2008-04-15 | Amgen Fremont Inc | Aus immunisierten xenomäusen stammende menschliche antikörper gegen il-8 |
EP0823941A4 (en) | 1995-04-28 | 2001-09-19 | Abgenix Inc | HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES |
US5830729A (en) | 1996-04-18 | 1998-11-03 | Institut Pasteur | I Sce I-induced gene replacement and gene conversion in embryonic stem cells |
US5916771A (en) | 1996-10-11 | 1999-06-29 | Abgenix, Inc. | Production of a multimeric protein by cell fusion method |
EP0942968B1 (en) | 1996-12-03 | 2008-02-27 | Amgen Fremont Inc. | Fully human antibodies that bind EGFR |
GB9625640D0 (en) | 1996-12-10 | 1997-01-29 | Celltech Therapeutics Ltd | Biological products |
PL193780B1 (pl) | 1997-04-14 | 2007-03-30 | Micromet Ag | Sposób wytwarzania receptora przeciw ludzkim antygenom, ludzkie przeciwciało i środek farmaceutyczny |
US6235883B1 (en) | 1997-05-05 | 2001-05-22 | Abgenix, Inc. | Human monoclonal antibodies to epidermal growth factor receptor |
WO1999029888A1 (en) | 1997-12-05 | 1999-06-17 | The Scripps Research Institute | Humanization of murine antibody |
JP4436130B2 (ja) | 2001-09-14 | 2010-03-24 | セレクティス | インビトロ直鎖化によるポリヌクレオチドのランダム組込 |
EP2559759A1 (en) | 2003-01-28 | 2013-02-20 | Cellectis | Custom-made meganuclease and use thereof |
JP2008513536A (ja) * | 2004-09-22 | 2008-05-01 | レセプター バイオロジックス インコーポレイテッド | プロガストリンに対するモノクローナル抗体 |
CN101460196A (zh) * | 2006-05-22 | 2009-06-17 | 国立医学与健康研究所 | 在结肠癌治疗中的前胃泌素抑制剂 |
WO2009054985A1 (en) | 2007-10-25 | 2009-04-30 | Sangamo Biosciences, Inc. | Methods and compositions for targeted integration |
SG10201704933PA (en) * | 2009-10-16 | 2017-07-28 | Inst Nat De La Sante Et De La Rech Medicale (Inserm) | Monoclonal antibodies to progastrin and their uses |
US8900817B2 (en) * | 2010-01-08 | 2014-12-02 | Les Laboratories Servier | Progastrin and liver pathologies |
US9487582B2 (en) | 2010-01-08 | 2016-11-08 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Methods for treating pancreatic cancer |
US9217032B2 (en) | 2010-01-08 | 2015-12-22 | Les Laboratoires Servier | Methods for treating colorectal cancer |
KR101570404B1 (ko) | 2010-03-24 | 2015-11-20 | 르 라보레또레 쎄르비에르 | 결장직장암 및 위창자암의 예방 |
KR101576174B1 (ko) | 2010-07-26 | 2015-12-09 | 르 라보레또레 쎄르비에르 | 간암 요법을 위한 방법 및 조성물 |
EA037015B1 (ru) | 2015-12-31 | 2021-01-27 | Прогастрин Э Кансер С.А Р.Л. | Применение и способ для профилактики или лечения рака яичников с использованием композиции, содержащей прогастринсвязывающее антитело |
JP7018885B2 (ja) | 2015-12-31 | 2022-02-14 | プロガストリン、エ、カンセル、エス、アー エル、エル | 食道癌の検出および治療のための組成物および方法 |
US20190011449A1 (en) | 2015-12-31 | 2019-01-10 | Progastrine Et Cancers S.À R.L. | Compositions and methods for detecting and treating gastric cancer |
CN114705858A (zh) * | 2015-12-31 | 2022-07-05 | Syncerus有限责任公司 | 用于评估癌症发生的风险的组合物和方法 |
US20190170752A1 (en) * | 2016-08-08 | 2019-06-06 | Beigene, Ltd. | Method for predicting efficacy of immune checkpoint inhibitors in cancer patients |
KR102616819B1 (ko) | 2017-03-30 | 2023-12-21 | 프로가스트린 에 캔서스 에스.에이 알.엘. | 폐암을 치료하기 위한 조성물 및 방법 |
KR102351556B1 (ko) | 2017-03-30 | 2022-01-14 | 프로가스트린 에 캔서스 에스.에이 알.엘. | 프로가스트린 결합 분자를 사용하는 전립선암의 검출 및 치료를 위한 조성물 및 방법 |
WO2019110662A1 (en) * | 2017-12-05 | 2019-06-13 | Progastrine Et Cancers S.À R.L. | Combination therapy between anti-progastrin antibody and immunotherapy to treat cancer |
-
2019
- 2019-02-27 EP EP19708997.2A patent/EP3759492A1/en active Pending
- 2019-02-27 SG SG11202008271QA patent/SG11202008271QA/en unknown
- 2019-02-27 US US16/975,271 patent/US20200400675A1/en active Pending
- 2019-02-27 AU AU2019228339A patent/AU2019228339A1/en active Pending
- 2019-02-27 TW TW108106874A patent/TW202000699A/zh unknown
- 2019-02-27 KR KR1020207027315A patent/KR20200144541A/ko not_active Application Discontinuation
- 2019-02-27 CN CN201980026882.XA patent/CN112368579B/zh active Active
- 2019-02-27 CA CA3092414A patent/CA3092414A1/en active Pending
- 2019-02-27 JP JP2020544818A patent/JP7485274B2/ja active Active
- 2019-02-27 WO PCT/EP2019/054878 patent/WO2019166499A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2021515210A (ja) | 2021-06-17 |
CA3092414A1 (en) | 2019-09-06 |
US20200400675A1 (en) | 2020-12-24 |
JP7485274B2 (ja) | 2024-05-16 |
WO2019166499A1 (en) | 2019-09-06 |
AU2019228339A1 (en) | 2020-09-10 |
CN112368579A (zh) | 2021-02-12 |
KR20200144541A (ko) | 2020-12-29 |
TW202000699A (zh) | 2020-01-01 |
EP3759492A1 (en) | 2021-01-06 |
CN112368579B (zh) | 2024-05-03 |
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