SG11202007498YA - Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants - Google Patents
Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplantsInfo
- Publication number
- SG11202007498YA SG11202007498YA SG11202007498YA SG11202007498YA SG11202007498YA SG 11202007498Y A SG11202007498Y A SG 11202007498YA SG 11202007498Y A SG11202007498Y A SG 11202007498YA SG 11202007498Y A SG11202007498Y A SG 11202007498YA SG 11202007498Y A SG11202007498Y A SG 11202007498YA
- Authority
- SG
- Singapore
- Prior art keywords
- solid organ
- organ transplants
- tissue transplantation
- specific tolerance
- thymus tissue
- Prior art date
Links
Classifications
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/26—Lymph; Lymph nodes; Thymus; Spleen; Splenocytes; Thymocytes
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
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- G01N2800/245—Transplantation related diseases, e.g. graft versus host disease
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
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- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
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- Zoology (AREA)
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- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Developmental Biology & Embryology (AREA)
- Transplantation (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- General Physics & Mathematics (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862634377P | 2018-02-23 | 2018-02-23 | |
PCT/US2019/019137 WO2019165197A1 (en) | 2018-02-23 | 2019-02-22 | Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11202007498YA true SG11202007498YA (en) | 2020-09-29 |
Family
ID=67687403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11202007498YA SG11202007498YA (en) | 2018-02-23 | 2019-02-22 | Cultured thymus tissue transplantation promotes donor-specific tolerance to allogeneic solid organ transplants |
Country Status (13)
Country | Link |
---|---|
US (1) | US20220079989A1 (ja) |
EP (1) | EP3755346A4 (ja) |
JP (2) | JP7499178B2 (ja) |
KR (1) | KR20210005543A (ja) |
CN (1) | CN112074277A (ja) |
AU (1) | AU2019225151A1 (ja) |
BR (1) | BR112020016614A2 (ja) |
CA (1) | CA3089593A1 (ja) |
IL (1) | IL276706A (ja) |
MX (1) | MX2020008590A (ja) |
RU (1) | RU2020124312A (ja) |
SG (1) | SG11202007498YA (ja) |
WO (1) | WO2019165197A1 (ja) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2021034650A1 (en) | 2019-08-19 | 2021-02-25 | Duke University & Medical Center | Methods of determining the suitability of cultured thymus tissue for implantation into humans and associated methods of use |
CN115287262B (zh) * | 2022-01-28 | 2024-04-02 | 浙江中医药大学 | 一种胸腺类器官微球及其制备方法与应用 |
WO2024042488A1 (en) | 2022-08-24 | 2024-02-29 | Enzyvant Therapeutics Gmbh | Thymic exosome assays, and methods of producing t cell depleted thymus tissue and uses thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6911220B1 (en) | 1992-02-19 | 2005-06-28 | The General Hospital Corporation | Allogeneic and xenogeneic transplantation |
US5766944A (en) * | 1996-12-31 | 1998-06-16 | Ruiz; Margaret Eileen | T cell differentiation of CD34+ stem cells in cultured thymic epithelial fragments |
AUPP977899A0 (en) | 1999-04-15 | 1999-05-13 | Monash University | Improvement of t cell mediated immunity |
US20040086508A1 (en) * | 2001-06-05 | 2004-05-06 | Advanced Biotherapy, Inc. | Treatment of organ transplant rejection |
KR20070100228A (ko) * | 2004-10-05 | 2007-10-10 | 제넨테크, 인크. | 혈관염의 치료 방법 |
ATE528390T1 (de) * | 2005-04-06 | 2011-10-15 | Univ Duke | Parathyroid- und thymustransplantation bei personen mit di-george-syndrom |
EP1993573A2 (en) * | 2006-01-13 | 2008-11-26 | Renovar, Inc. | Systems and methods for monitoring immune responses and predicting outcomes in transplant recipients |
WO2012092578A1 (en) * | 2010-12-31 | 2012-07-05 | The Trustees Of Columbia University In The City Of New York | Generation of autologous t-cells in mice |
JP6129155B2 (ja) * | 2011-04-12 | 2017-05-17 | ライジェル ファーマシューティカルズ, インコーポレイテッド | 同種移植片拒絶反応を抑制する方法 |
CA2927319C (en) * | 2013-10-15 | 2023-03-28 | Regeneron Pharmaceuticals, Inc. | High resolution allele identification |
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2019
- 2019-02-22 AU AU2019225151A patent/AU2019225151A1/en active Pending
- 2019-02-22 CA CA3089593A patent/CA3089593A1/en active Pending
- 2019-02-22 WO PCT/US2019/019137 patent/WO2019165197A1/en unknown
- 2019-02-22 MX MX2020008590A patent/MX2020008590A/es unknown
- 2019-02-22 CN CN201980013250.XA patent/CN112074277A/zh active Pending
- 2019-02-22 KR KR1020207023608A patent/KR20210005543A/ko not_active Application Discontinuation
- 2019-02-22 JP JP2020543913A patent/JP7499178B2/ja active Active
- 2019-02-22 BR BR112020016614-6A patent/BR112020016614A2/pt unknown
- 2019-02-22 SG SG11202007498YA patent/SG11202007498YA/en unknown
- 2019-02-22 RU RU2020124312A patent/RU2020124312A/ru unknown
- 2019-02-22 EP EP19757113.6A patent/EP3755346A4/en active Pending
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2020
- 2020-08-13 IL IL276706A patent/IL276706A/en unknown
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2021
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2024
- 2024-01-17 JP JP2024005418A patent/JP2024041955A/ja active Pending
Also Published As
Publication number | Publication date |
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AU2019225151A1 (en) | 2020-08-20 |
KR20210005543A (ko) | 2021-01-14 |
MX2020008590A (es) | 2020-09-21 |
JP7499178B2 (ja) | 2024-06-13 |
US20220079989A1 (en) | 2022-03-17 |
EP3755346A1 (en) | 2020-12-30 |
CA3089593A1 (en) | 2019-08-29 |
JP2024041955A (ja) | 2024-03-27 |
RU2020124312A (ru) | 2022-03-23 |
JP2021516224A (ja) | 2021-07-01 |
WO2019165197A1 (en) | 2019-08-29 |
BR112020016614A2 (pt) | 2020-12-22 |
IL276706A (en) | 2020-09-30 |
CN112074277A (zh) | 2020-12-11 |
EP3755346A4 (en) | 2022-03-09 |
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