SG11202003512YA - Stable liquid composition of ketoprofen, salts and enantiomers thereof - Google Patents

Stable liquid composition of ketoprofen, salts and enantiomers thereof

Info

Publication number
SG11202003512YA
SG11202003512YA SG11202003512YA SG11202003512YA SG11202003512YA SG 11202003512Y A SG11202003512Y A SG 11202003512YA SG 11202003512Y A SG11202003512Y A SG 11202003512YA SG 11202003512Y A SG11202003512Y A SG 11202003512YA SG 11202003512Y A SG11202003512Y A SG 11202003512YA
Authority
SG
Singapore
Prior art keywords
ketoprofen
enantiomers
salts
liquid composition
stable liquid
Prior art date
Application number
SG11202003512YA
Other languages
English (en)
Inventor
Danilo D'amico
Leonardo Marchitto
Lorella Ragni
Luca Donati
Vincenzo Russo
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Publication of SG11202003512YA publication Critical patent/SG11202003512YA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
SG11202003512YA 2017-11-30 2018-11-28 Stable liquid composition of ketoprofen, salts and enantiomers thereof SG11202003512YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17204585 2017-11-30
PCT/EP2018/082754 WO2019105957A1 (en) 2017-11-30 2018-11-28 Stable liquid composition of ketoprofen, salts and enantiomers thereof

Publications (1)

Publication Number Publication Date
SG11202003512YA true SG11202003512YA (en) 2020-05-28

Family

ID=60661746

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003512YA SG11202003512YA (en) 2017-11-30 2018-11-28 Stable liquid composition of ketoprofen, salts and enantiomers thereof

Country Status (13)

Country Link
US (1) US20210260003A9 (zh)
EP (1) EP3716944A1 (zh)
JP (1) JP2021504306A (zh)
KR (1) KR20200094161A (zh)
CN (1) CN111526868A (zh)
AU (1) AU2018376176A1 (zh)
BR (1) BR112020009719A2 (zh)
CA (1) CA3079530A1 (zh)
EA (1) EA202091229A1 (zh)
IL (1) IL274672A (zh)
MX (1) MX2020005133A (zh)
SG (1) SG11202003512YA (zh)
WO (1) WO2019105957A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024071979A1 (ko) * 2022-09-29 2024-04-04 주식회사태준제약 브리모니딘을 포함하는 안과용 조성물

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243342B (it) * 1990-07-13 1994-06-10 Farcon Ag Composizioni farmaceutiche orali liquide ad attivita' antiinfiammatoria
US5183829A (en) 1991-09-27 1993-02-02 Applied Analytical Industries, Inc. Oral liquid compositions of non-steroidal anti-inflammatory drugs
WO1997018245A1 (en) 1995-11-14 1997-05-22 Farmarc Nederland B.V. Complex of naproxen and beta-cyclodextrin
IT1277741B1 (it) 1995-12-28 1997-11-12 Dompe Spa Composizioni farmaceutiche parenterali contenenti sali di alchilammonio di acidi 2-arilpropionici
EP1024808A1 (en) 1998-04-11 2000-08-09 Errekappa Euroterapici S.p.a. Pharmaceutical preparations containing hydrosoluble ketoprofen salts and their application
WO2004005454A1 (ja) 2002-07-05 2004-01-15 Able Corporation ヒドロキシアパタイトを用いた細胞培養装置及び細胞モジュール
ITMI20032523A1 (it) 2003-12-19 2005-06-20 Acraf Forma di dosaggio per uso orale comprendente un farmaco
AU2007230718B2 (en) 2006-03-28 2012-05-10 Javelin Pharmaceuticals, Inc. Formulations of low dose non-steroidal anti-inflammatory drugs and beta-cyclodextrin
EP1974751A1 (en) * 2007-03-26 2008-10-01 The Jordanian Pharmaceutical Manufacturing Co. Formulations for non-steroidal anti-inflammatory drugs
FR2950533B1 (fr) 2009-09-28 2012-01-13 Maco Pharma Sa Formulation liquide, stable, prete a l'emploi de ketoprofene
TR201103183A1 (tr) * 2011-04-01 2012-10-22 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Ketoprofen ve metilsülfonilmetanın topikal farmasötik bileşimleri.
BR112013029790A2 (pt) * 2011-05-20 2017-01-17 Aventis Pharma Sa composição farmacêutica compreendendo cetoprofeno
US8822537B2 (en) * 2012-09-27 2014-09-02 Achelios Therapeutics, Inc. Topical ketoprofen composition

Also Published As

Publication number Publication date
CN111526868A (zh) 2020-08-11
AU2018376176A1 (en) 2020-07-02
IL274672A (en) 2020-06-30
WO2019105957A1 (en) 2019-06-06
JP2021504306A (ja) 2021-02-15
BR112020009719A2 (pt) 2020-10-27
KR20200094161A (ko) 2020-08-06
EP3716944A1 (en) 2020-10-07
US20200281879A1 (en) 2020-09-10
CA3079530A1 (en) 2019-06-06
US20210260003A9 (en) 2021-08-26
MX2020005133A (es) 2020-11-06
EA202091229A1 (ru) 2020-08-19

Similar Documents

Publication Publication Date Title
EP3200586A4 (en) Antimicrobial coating for long-term disinfection of surfaces
ZA202003664B (en) Ppar agonists, compounds, pharmaceutical compositions, and methods of use thereof
HK1258704A1 (zh) 藥物組合物和塗料
ZA201907313B (en) Stable liquid pharmaceutical composition
EP3294205A4 (en) DISPENSER FOR DENTAL SOLUTION AND METHOD OF USE
DK3241551T3 (da) Farmaceutisk sammensætning til behandling af kræft, indeholdende lactatmetalsalt
EP3395325A4 (en) LIQUID COSMETIC COMPOSITION
EP3297636A4 (en) Pharmaceutical composition of carboplatin based co-crystals and use thereof
GB201718468D0 (en) Stable liquid pharmaceutical compositions of bortezomb
IL274672A (en) A stable liquid preparation of ketoprofen, its salts and enantiomers
SI3349594T1 (sl) Sestavek nadomestka soli in uporaba le-tega
EP3344242A4 (en) MULTIPARTICULAR STABLE PHARMACEUTICAL COMPOSITION OF ROSUVASTATIN
EP3156040A4 (en) Cosmetic composition containing 3-o-alkyl-l-ascorbic acid or salt thereof
ZA201907515B (en) Process for the preparation of pirlindole enantiomers and its salts
EP3231422A4 (en) Application of atractylenolide compound or derivative thereof and anti-platelet aggregation drug
HK1254738A1 (zh) 用於進行最小量潤滑的組合物及其用途
SG11201708527RA (en) Manufacture of organopolysulfides and salts thereof
ZA201908264B (en) Formulations of homotaurines and salts thereof
HK1257509A1 (zh) 包含萘醌腙或其一種鹽的脈衝釋放藥物組合物
LT3612535T (lt) Pirlindolo enantiomerų ir jo druskų gavimo būdas
PL3612535T3 (pl) Sposób otrzymywania enancjomerów pirlindolu i jego soli
GB201621771D0 (en) New salts of compounds and uses thereof
PL3185855T3 (pl) Tabletka powlekana filmem do leczenia ostrego bólu