SG11202003512YA - Stable liquid composition of ketoprofen, salts and enantiomers thereof - Google Patents

Stable liquid composition of ketoprofen, salts and enantiomers thereof

Info

Publication number
SG11202003512YA
SG11202003512YA SG11202003512YA SG11202003512YA SG11202003512YA SG 11202003512Y A SG11202003512Y A SG 11202003512YA SG 11202003512Y A SG11202003512Y A SG 11202003512YA SG 11202003512Y A SG11202003512Y A SG 11202003512YA SG 11202003512Y A SG11202003512Y A SG 11202003512YA
Authority
SG
Singapore
Prior art keywords
ketoprofen
enantiomers
salts
liquid composition
stable liquid
Prior art date
Application number
SG11202003512YA
Inventor
Danilo D'amico
Leonardo Marchitto
Lorella Ragni
Luca Donati
Vincenzo Russo
Original Assignee
Acraf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Acraf filed Critical Acraf
Publication of SG11202003512YA publication Critical patent/SG11202003512YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
SG11202003512YA 2017-11-30 2018-11-28 Stable liquid composition of ketoprofen, salts and enantiomers thereof SG11202003512YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17204585 2017-11-30
PCT/EP2018/082754 WO2019105957A1 (en) 2017-11-30 2018-11-28 Stable liquid composition of ketoprofen, salts and enantiomers thereof

Publications (1)

Publication Number Publication Date
SG11202003512YA true SG11202003512YA (en) 2020-05-28

Family

ID=60661746

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202003512YA SG11202003512YA (en) 2017-11-30 2018-11-28 Stable liquid composition of ketoprofen, salts and enantiomers thereof

Country Status (13)

Country Link
US (1) US20210260003A9 (en)
EP (1) EP3716944A1 (en)
JP (1) JP2021504306A (en)
KR (1) KR20200094161A (en)
CN (1) CN111526868A (en)
AU (1) AU2018376176A1 (en)
BR (1) BR112020009719A2 (en)
CA (1) CA3079530A1 (en)
EA (1) EA202091229A1 (en)
IL (1) IL274672A (en)
MX (1) MX2020005133A (en)
SG (1) SG11202003512YA (en)
WO (1) WO2019105957A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024071979A1 (en) * 2022-09-29 2024-04-04 주식회사태준제약 Ophthalmic composition comprising brimonidine

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243342B (en) * 1990-07-13 1994-06-10 Farcon Ag ORAL PHARMACEUTICAL COMPOSITIONS FOR LIQUID ANTI-INFLAMMATORY ACTIVITIES
US5183829A (en) 1991-09-27 1993-02-02 Applied Analytical Industries, Inc. Oral liquid compositions of non-steroidal anti-inflammatory drugs
WO1997018245A1 (en) 1995-11-14 1997-05-22 Farmarc Nederland B.V. Complex of naproxen and beta-cyclodextrin
IT1277741B1 (en) 1995-12-28 1997-11-12 Dompe Spa PARENTERAL PHARMACEUTICAL COMPOSITIONS CONTAINING ALKYLAMMONIUM SALTS OF 2-ARYLPROPIONIC ACIDS
CN1263464A (en) 1998-04-11 2000-08-16 伊利卡帕·尤罗特拉皮西有限公司 Pharmaceutical preparations containing hydrosoluble ketoprofen salts and their application
AU2003246256A1 (en) 2002-07-05 2004-01-23 Able Corporation Cell culture apparatus using hydroxyapatite and cell module
ITMI20032523A1 (en) 2003-12-19 2005-06-20 Acraf DOSAGE FORM FOR ORAL USE INCLUDING A DRUG
KR20090010953A (en) 2006-03-28 2009-01-30 자블린 파머슈티칼스 인코포레이티드 Formulations of low dose non-steroidal anti-inflammatory drugs and beta-cyclodextrin
EP1974751A1 (en) * 2007-03-26 2008-10-01 The Jordanian Pharmaceutical Manufacturing Co. Formulations for non-steroidal anti-inflammatory drugs
FR2950533B1 (en) 2009-09-28 2012-01-13 Maco Pharma Sa LIQUID FORMULATION, STABLE, READY TO USE KETOPROFEN
TR201103183A1 (en) * 2011-04-01 2012-10-22 Sanovel İlaç Sanayi̇ Ve Ti̇caret Anoni̇m Şi̇rketi̇ Topical pharmaceutical compositions of ketoprofen and methylsulfonylmethane.
JP2014513710A (en) * 2011-05-20 2014-06-05 アバンテイス・フアルマ・エス・アー Pharmaceutical composition comprising ketoprofen
US8822537B2 (en) * 2012-09-27 2014-09-02 Achelios Therapeutics, Inc. Topical ketoprofen composition

Also Published As

Publication number Publication date
MX2020005133A (en) 2020-11-06
JP2021504306A (en) 2021-02-15
WO2019105957A1 (en) 2019-06-06
EA202091229A1 (en) 2020-08-19
BR112020009719A2 (en) 2020-10-27
AU2018376176A1 (en) 2020-07-02
IL274672A (en) 2020-06-30
US20210260003A9 (en) 2021-08-26
EP3716944A1 (en) 2020-10-07
CN111526868A (en) 2020-08-11
KR20200094161A (en) 2020-08-06
CA3079530A1 (en) 2019-06-06
US20200281879A1 (en) 2020-09-10

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