SG11202000549TA - Mavacamten for use in the treatment of hypertrophic cardiomyopathy - Google Patents

Mavacamten for use in the treatment of hypertrophic cardiomyopathy

Info

Publication number
SG11202000549TA
SG11202000549TA SG11202000549TA SG11202000549TA SG11202000549TA SG 11202000549T A SG11202000549T A SG 11202000549TA SG 11202000549T A SG11202000549T A SG 11202000549TA SG 11202000549T A SG11202000549T A SG 11202000549TA SG 11202000549T A SG11202000549T A SG 11202000549TA
Authority
SG
Singapore
Prior art keywords
mavacamten
treatment
hypertrophic cardiomyopathy
hypertrophic
cardiomyopathy
Prior art date
Application number
SG11202000549TA
Other languages
English (en)
Inventor
Marc J Semigran
June H Lee
Joseph Lambing
Eric Green
Marc Evanchik
Original Assignee
Myokardia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Myokardia Inc filed Critical Myokardia Inc
Publication of SG11202000549TA publication Critical patent/SG11202000549TA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
SG11202000549TA 2017-08-04 2018-08-03 Mavacamten for use in the treatment of hypertrophic cardiomyopathy SG11202000549TA (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762541591P 2017-08-04 2017-08-04
US201762584537P 2017-11-10 2017-11-10
US201862639922P 2018-03-07 2018-03-07
US201862671585P 2018-05-15 2018-05-15
PCT/US2018/045180 WO2019028360A1 (fr) 2017-08-04 2018-08-03 Mavacamten destiné à être utilisé dans le traitement de la cardiomyopathie hypertrophique

Publications (1)

Publication Number Publication Date
SG11202000549TA true SG11202000549TA (en) 2020-02-27

Family

ID=63350605

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10202112960QA SG10202112960QA (en) 2017-08-04 2018-08-03 Mavacamten for use in the treatment of hypertrophic cardiomyopathy
SG11202000549TA SG11202000549TA (en) 2017-08-04 2018-08-03 Mavacamten for use in the treatment of hypertrophic cardiomyopathy

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG10202112960QA SG10202112960QA (en) 2017-08-04 2018-08-03 Mavacamten for use in the treatment of hypertrophic cardiomyopathy

Country Status (15)

Country Link
US (3) US20200054636A1 (fr)
EP (1) EP3661514A1 (fr)
JP (2) JP2020529996A (fr)
KR (1) KR20200035973A (fr)
CN (2) CN118593507A (fr)
AU (2) AU2018311974B2 (fr)
CA (1) CA3071948A1 (fr)
IL (1) IL272300A (fr)
MA (1) MA49760A (fr)
MX (2) MX2020001406A (fr)
RU (1) RU2020109345A (fr)
SG (2) SG10202112960QA (fr)
TW (1) TW201916882A (fr)
UY (1) UY37834A (fr)
WO (1) WO2019028360A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3740481T3 (da) 2018-01-19 2024-07-08 Cytokinetics Inc Dihydrobenzofuran- og indenanaloger som hjertesarkomerinhibitorer
WO2020005887A1 (fr) 2018-06-26 2020-01-02 Cytokinetics, Inc. Inhibiteurs de sarcomères cardiaques
WO2020257609A1 (fr) * 2019-06-21 2020-12-24 MyoKardia, Inc. Diagnostics et traitements pour une maladie cardiaque
CN110698415B (zh) * 2019-10-21 2023-05-09 上海先行医药开发有限公司 一种肌球蛋白抑制剂及其制备方法和用途
CA3157629A1 (fr) * 2019-11-10 2021-05-14 MyoKardia, Inc. Methodes de traitement comprenant un modulateur de myosine
EP4097091B1 (fr) * 2020-01-28 2024-09-18 Assia Chemical Industries Ltd. Formes solides de mavacamten et leur procédé de préparation
JP2023540485A (ja) * 2020-08-28 2023-09-25 マイオカーディア,インク ミオシンモジュレーターによる治療方法
KR20230110538A (ko) 2020-11-20 2023-07-24 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 트라이아진 다이온 유도체, 이의 제조 방법 및 의약에서 이의 용도
US20240082248A1 (en) * 2021-02-01 2024-03-14 Dr. Reddy's Laboratories Limited Process for preparation of mavacamten and solid state forms thereof
WO2022187501A1 (fr) 2021-03-04 2022-09-09 Cytokinetics, Inc. Inhibiteurs de sarcomes cardiaques
CN112939876A (zh) * 2021-03-10 2021-06-11 杭州科巢生物科技有限公司 Mavacamten的晶型I及其制备方法
WO2022189599A1 (fr) 2021-03-12 2022-09-15 Sandoz Ag Formes cristallines de mavacamten pour le traitement de la cmh
AU2022312506A1 (en) * 2021-07-16 2024-02-01 Cytokinetics, Inc. Methods for treating hypertrophic cardiomyopathy
WO2024097284A1 (fr) * 2022-11-02 2024-05-10 MyoKardia, Inc. Mavacamten et ses dérivés destinés à être utilisés dans le traitement d'un dysfonctionnement atrial

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL302299A (en) * 2013-06-21 2023-06-01 Myokardia Inc Pyrimidinedione compounds against cardiac disorders

Also Published As

Publication number Publication date
JP2020529996A (ja) 2020-10-15
TW201916882A (zh) 2019-05-01
WO2019028360A1 (fr) 2019-02-07
RU2020109345A (ru) 2021-09-06
MX2024000348A (es) 2024-01-26
MA49760A (fr) 2020-06-10
CA3071948A1 (fr) 2019-02-07
IL272300A (en) 2020-03-31
JP2023065372A (ja) 2023-05-12
AU2018311974B2 (en) 2024-03-07
AU2024203872A1 (en) 2024-06-27
CN118593507A (zh) 2024-09-06
CN111182901A (zh) 2020-05-19
UY37834A (es) 2019-02-28
US20220226324A1 (en) 2022-07-21
SG10202112960QA (en) 2021-12-30
AU2018311974A1 (en) 2020-02-06
KR20200035973A (ko) 2020-04-06
EP3661514A1 (fr) 2020-06-10
US20200054636A1 (en) 2020-02-20
US20220313695A1 (en) 2022-10-06
MX2020001406A (es) 2020-03-09

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