SG11201912255RA - Detector with reduced fluorescence range noise - Google Patents

Detector with reduced fluorescence range noise

Info

Publication number
SG11201912255RA
SG11201912255RA SG11201912255RA SG11201912255RA SG11201912255RA SG 11201912255R A SG11201912255R A SG 11201912255RA SG 11201912255R A SG11201912255R A SG 11201912255RA SG 11201912255R A SG11201912255R A SG 11201912255RA SG 11201912255R A SG11201912255R A SG 11201912255RA
Authority
SG
Singapore
Prior art keywords
detector
reduced fluorescence
range noise
fluorescence range
noise
Prior art date
Application number
SG11201912255RA
Other languages
English (en)
Inventor
Tracy H Fung
Poorya Sabounchi
Bernard Hirschbein
Joseph Pinto
Tarun Khurana
Randall Smith
Wenyi Feng
Original Assignee
Illumina Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Illumina Inc filed Critical Illumina Inc
Publication of SG11201912255RA publication Critical patent/SG11201912255RA/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6486Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G01N21/6454Individual samples arranged in a regular 2D-array, e.g. multiwell plates using an integrated detector array
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6402Atomic fluorescence; Laser induced fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B19/00Condensers, e.g. light collectors or similar non-imaging optics
    • G02B19/0004Condensers, e.g. light collectors or similar non-imaging optics characterised by the optical means employed
    • G02B19/0019Condensers, e.g. light collectors or similar non-imaging optics characterised by the optical means employed having reflective surfaces only (e.g. louvre systems, systems with multiple planar reflectors)
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B19/00Condensers, e.g. light collectors or similar non-imaging optics
    • G02B19/0033Condensers, e.g. light collectors or similar non-imaging optics characterised by the use
    • G02B19/0076Condensers, e.g. light collectors or similar non-imaging optics characterised by the use for use with a detector
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B5/00Optical elements other than lenses
    • G02B5/20Filters
    • G02B5/22Absorbing filters
    • G02B5/223Absorbing filters containing organic substances, e.g. dyes, inks or pigments
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01LSEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L27/00Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate
    • H01L27/14Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including semiconductor components sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation and specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation
    • H01L27/144Devices controlled by radiation
    • H01L27/146Imager structures
    • H01L27/14601Structural or functional details thereof
    • H01L27/1462Coatings
    • H01L27/14621Colour filter arrangements
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01LSEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L27/00Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate
    • H01L27/14Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including semiconductor components sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation and specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation
    • H01L27/144Devices controlled by radiation
    • H01L27/146Imager structures
    • H01L27/14601Structural or functional details thereof
    • H01L27/14625Optical elements or arrangements associated with the device
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01LSEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L27/00Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate
    • H01L27/14Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including semiconductor components sensitive to infrared radiation, light, electromagnetic radiation of shorter wavelength or corpuscular radiation and specially adapted either for the conversion of the energy of such radiation into electrical energy or for the control of electrical energy by such radiation
    • H01L27/144Devices controlled by radiation
    • H01L27/146Imager structures
    • H01L27/14643Photodiode arrays; MOS imagers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6471Special filters, filter wheel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00Features of devices classified in G01N21/00
    • G01N2201/08Optical fibres; light guides

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Power Engineering (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Electromagnetism (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Computer Hardware Design (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Optical Measuring Cells (AREA)
  • Optical Filters (AREA)
SG11201912255RA 2017-12-28 2018-11-30 Detector with reduced fluorescence range noise SG11201912255RA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762611464P 2017-12-28 2017-12-28
US201862644804P 2018-03-19 2018-03-19
PCT/US2018/063395 WO2019133182A1 (en) 2017-12-28 2018-11-30 Detector with reduced fluorescence range noise

Publications (1)

Publication Number Publication Date
SG11201912255RA true SG11201912255RA (en) 2020-01-30

Family

ID=67058128

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201912255RA SG11201912255RA (en) 2017-12-28 2018-11-30 Detector with reduced fluorescence range noise

Country Status (23)

Country Link
US (5) US10551317B2 (ru)
EP (2) EP3978908A1 (ru)
JP (1) JP6827570B2 (ru)
KR (2) KR102583715B1 (ru)
CN (3) CN209624391U (ru)
AU (2) AU2018397465A1 (ru)
BR (1) BR112019028286B1 (ru)
CA (2) CA3191105A1 (ru)
CL (1) CL2019003784A1 (ru)
CO (1) CO2019014476A2 (ru)
CR (1) CR20190584A (ru)
DK (1) DK3732468T3 (ru)
ES (1) ES2906809T3 (ru)
IL (1) IL271293B (ru)
MX (1) MX2019015855A (ru)
MY (1) MY194752A (ru)
PH (1) PH12019502900A1 (ru)
RU (1) RU2738311C1 (ru)
SA (1) SA519410862B1 (ru)
SG (1) SG11201912255RA (ru)
TW (1) TWI698638B (ru)
WO (1) WO2019133182A1 (ru)
ZA (1) ZA201908274B (ru)

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US11557625B2 (en) * 2020-04-20 2023-01-17 Omnivision Technologies, Inc. Image sensors with embedded wells for accommodating light emitters
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Also Published As

Publication number Publication date
US11852586B2 (en) 2023-12-26
CR20190584A (es) 2020-03-06
TWI698638B (zh) 2020-07-11
SA519410862B1 (ar) 2022-09-05
EP3732468A4 (en) 2020-12-02
US20240094125A1 (en) 2024-03-21
WO2019133182A1 (en) 2019-07-04
TW201930878A (zh) 2019-08-01
AU2018397465A1 (en) 2020-01-16
CL2019003784A1 (es) 2020-07-10
KR102583715B1 (ko) 2023-10-04
US20200166461A1 (en) 2020-05-28
AU2021203297A1 (en) 2021-06-17
US11333604B2 (en) 2022-05-17
US20190204226A1 (en) 2019-07-04
CA3067249C (en) 2023-04-25
BR112019028286A2 (pt) 2020-07-14
CA3191105A1 (en) 2019-07-04
US20220260492A1 (en) 2022-08-18
KR20200017431A (ko) 2020-02-18
CN115078317A (zh) 2022-09-20
CA3067249A1 (en) 2019-07-04
MX2019015855A (es) 2021-04-07
CN109975255B (zh) 2022-04-19
IL271293A (en) 2020-01-30
US10883937B2 (en) 2021-01-05
CO2019014476A2 (es) 2020-04-13
US20210003505A1 (en) 2021-01-07
BR112019028286B1 (pt) 2021-10-26
IL271293B (en) 2021-03-25
EP3732468A1 (en) 2020-11-04
ES2906809T3 (es) 2022-04-20
ZA201908274B (en) 2021-04-28
KR102261632B1 (ko) 2021-06-07
AU2021203297B2 (en) 2023-05-18
EP3732468B1 (en) 2021-12-15
NZ759983A (en) 2021-08-27
EP3978908A1 (en) 2022-04-06
DK3732468T3 (da) 2022-02-14
CN109975255A (zh) 2019-07-05
US10551317B2 (en) 2020-02-04
JP6827570B2 (ja) 2021-02-10
PH12019502900A1 (en) 2020-09-14
MY194752A (en) 2022-12-15
JP2020531797A (ja) 2020-11-05
RU2738311C1 (ru) 2020-12-11
CN209624391U (zh) 2019-11-12
KR20210066028A (ko) 2021-06-04

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