SG11201909562PA - Treatment of a bacterial vaginal infection - Google Patents

Treatment of a bacterial vaginal infection

Info

Publication number
SG11201909562PA
SG11201909562PA SG11201909562PA SG11201909562PA SG 11201909562P A SG11201909562P A SG 11201909562PA SG 11201909562P A SG11201909562P A SG 11201909562PA SG 11201909562P A SG11201909562P A SG 11201909562PA
Authority
SG
Singapore
Prior art keywords
international
vaginal infection
pct
treatment
rule
Prior art date
Application number
Inventor
Sylwia Berdzik-Kalarus
Daniel Sulikowski
Original Assignee
Adamed Pharma S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adamed Pharma S A filed Critical Adamed Pharma S A
Publication of SG11201909562PA publication Critical patent/SG11201909562PA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/04—Drugs for disorders of the urinary system for urolithiasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 18 October 2018 (18.10.2018) W I PO I PCT omit VIII °nolo OH imiononoiliflo oimIE (10) International Publication Number WO 2018/188992 Al (51) International Patent Classification: A61K 31/4178 (2006.01) A61K 9/00 (2006.01) A61K 31/4164 (2006.01) A61K 9/20 (2006.01) A61K 31/7048 (2006.01) A61K 47/06 (2006.01) A61K 45/06 (2006.01) A61P 31/04 (2006.01) (21) International Application Number: Published: — with international search report (Art. 21(3)) PCT/EP2018/058508 (22) International Filing Date: 03 April 2018 (03.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 17461524.5 14 April 2017 (14.04.2017) EP (71) Applicant: ADAMED PHARMA S.A. [PL/PL]; Pienkow, ul. Mariana Adamkiewicza 6A, 05-152 Czosnow (PL). (72) Inventors: BERDZIK-KALARUS, Sylwia; ul. Czajek 14, 40-534 Katowice (PL). SULIKOWSKI, Daniel; ul. Oby- watelska 34, 02-409 Warszawa (PL). (74) Agent: SULIKOWSKI, Daniel; ADMARKA SP. Z 0.0., Pienkow 149, 05-152 Czosnow (PL). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Declarations under Rule 4.17: as to the identity of the inventor (Rule 4.17(i)) as to applicant's entitlement to apply for and be granted a patent (Rule 4.170) 0\ 00 00 1-1 (54) Title: TREATMENT OF A BACTERIAL VAGINAL INFECTION O (57) : The present invention relates to furazidin for vaginal use in the treatment of a bacterial vaginal infection. Preferably, the bacterial vaginal infection is caused by Gardnerella vaginalis and/or Atopobium vaginae bacteria. O
SG11201909562P 2017-04-14 2018-04-03 Treatment of a bacterial vaginal infection SG11201909562PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17461524.5A EP3388063A1 (en) 2017-04-14 2017-04-14 Treatment of a bacterial vaginal infection
PCT/EP2018/058508 WO2018188992A1 (en) 2017-04-14 2018-04-03 Treatment of a bacterial vaginal infection

Publications (1)

Publication Number Publication Date
SG11201909562PA true SG11201909562PA (en) 2019-11-28

Family

ID=58578922

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201909562P SG11201909562PA (en) 2017-04-14 2018-04-03 Treatment of a bacterial vaginal infection

Country Status (18)

Country Link
US (2) US11684608B2 (en)
EP (2) EP3388063A1 (en)
BR (1) BR112019021404A2 (en)
CO (1) CO2019011305A2 (en)
CR (1) CR20190466A (en)
DK (1) DK3609493T3 (en)
EA (1) EA201992448A1 (en)
ES (1) ES2984250T3 (en)
FI (1) FI3609493T3 (en)
LT (1) LT3609493T (en)
MX (1) MX2019012232A (en)
MY (1) MY196293A (en)
PH (1) PH12019502332A1 (en)
PL (1) PL3609493T3 (en)
PT (1) PT3609493T (en)
RS (1) RS65819B1 (en)
SG (1) SG11201909562PA (en)
WO (1) WO2018188992A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3388063A1 (en) * 2017-04-14 2018-10-17 Adamed sp. z o.o. Treatment of a bacterial vaginal infection
US11529346B2 (en) * 2020-06-18 2022-12-20 National Medical Supply, LLC Vaginal gel

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4500516A (en) * 1982-10-22 1985-02-19 Institut Organicheskogo Sinteza Akademii Nauk Latviiskoi Ssr Antibacterial pharmaceutical composition
US4542020A (en) * 1984-08-17 1985-09-17 E. R. Squibb & Sons, Inc. Long-lasting adhesive antifungal suppositories
CA2008775C (en) 1989-02-24 1998-12-22 Alberto Ferro Nail lacquer
WO2002014493A2 (en) * 2000-08-11 2002-02-21 Whitehead Institute For Biomedical Research Control of biofilm development
JP2004067599A (en) * 2002-08-07 2004-03-04 Kunihiko Tominaga In-vagina detergent
WO2012106264A2 (en) * 2011-01-31 2012-08-09 The Trustees Of Columbia University In The City Of New York Treatment and prevention of bacterial vaginosis and gardnerella vaginalis infections
EP3388063A1 (en) 2017-04-14 2018-10-17 Adamed sp. z o.o. Treatment of a bacterial vaginal infection

Also Published As

Publication number Publication date
ES2984250T3 (en) 2024-10-29
EP3609493B1 (en) 2024-05-15
EP3388063A1 (en) 2018-10-17
BR112019021404A2 (en) 2020-04-28
PL3609493T3 (en) 2024-09-02
EA201992448A1 (en) 2020-02-17
WO2018188992A1 (en) 2018-10-18
US20200078337A1 (en) 2020-03-12
EP3609493A1 (en) 2020-02-19
RS65819B1 (en) 2024-09-30
CO2019011305A2 (en) 2019-10-31
LT3609493T (en) 2024-08-26
US11684608B2 (en) 2023-06-27
PH12019502332A1 (en) 2020-10-12
PT3609493T (en) 2024-08-14
US20230270725A1 (en) 2023-08-31
MX2019012232A (en) 2019-11-28
MY196293A (en) 2023-03-24
DK3609493T3 (en) 2024-08-05
FI3609493T3 (en) 2024-08-13
CR20190466A (en) 2019-11-15

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