SG11201909394PA - Compositions and methods for improving sample identification in indexed nucleic acid libraries - Google Patents
Compositions and methods for improving sample identification in indexed nucleic acid librariesInfo
- Publication number
- SG11201909394PA SG11201909394PA SG11201909394PA SG11201909394PA SG 11201909394P A SG11201909394P A SG 11201909394PA SG 11201909394P A SG11201909394P A SG 11201909394PA SG 11201909394P A SG11201909394P A SG 11201909394PA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- illumina
- nucleic acid
- compositions
- methods
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B20/00—Methods specially adapted for identifying library members
- C40B20/04—Identifying library members by means of a tag, label, or other readable or detectable entity associated with the library members, e.g. decoding processes
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
- C40B50/16—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support involving encoding steps
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
- C40B50/18—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support using a particular method of attachment to the solid support
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B80/00—Linkers or spacers specially adapted for combinatorial chemistry or libraries, e.g. traceless linkers or safety-catch linkers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762488833P | 2017-04-23 | 2017-04-23 | |
PCT/US2018/028881 WO2018200386A1 (fr) | 2017-04-23 | 2018-04-23 | Compositions et procédés pour améliorer l'identification d'échantillons dans des bibliothèques d'acides nucléiques indexés |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201909394PA true SG11201909394PA (en) | 2019-11-28 |
Family
ID=62117118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201909394P SG11201909394PA (en) | 2017-04-23 | 2018-04-23 | Compositions and methods for improving sample identification in indexed nucleic acid libraries |
Country Status (10)
Country | Link |
---|---|
US (2) | US10934584B2 (fr) |
EP (2) | EP3615691B1 (fr) |
CN (1) | CN110770353A (fr) |
AU (3) | AU2018260633B2 (fr) |
CA (1) | CA3059952C (fr) |
DK (1) | DK3615691T3 (fr) |
ES (2) | ES2882608T3 (fr) |
FI (1) | FI3842545T3 (fr) |
SG (1) | SG11201909394PA (fr) |
WO (1) | WO2018200386A1 (fr) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2893528T3 (es) | 2017-04-23 | 2022-02-09 | Illumina Cambridge Ltd | Composiciones y métodos para mejorar la identificación de muestras en colecciones de ácidos nucleicos indexadas |
EP3913053A1 (fr) | 2017-04-23 | 2021-11-24 | Illumina Cambridge Limited | Compositions et procédés permettant d'améliorer l'identification d'échantillons dans des bibliothèques d'acides nucléiques indexés |
WO2018200386A1 (fr) | 2017-04-23 | 2018-11-01 | Illumina, Inc. | Compositions et procédés pour améliorer l'identification d'échantillons dans des bibliothèques d'acides nucléiques indexés |
WO2018197950A1 (fr) | 2017-04-23 | 2018-11-01 | Illumina Cambridge Limited | Compositions et procédés pour améliorer l'identification d'échantillons dans des bibliothèques d'acides nucléiques indexées |
US10081829B1 (en) | 2017-06-13 | 2018-09-25 | Genetics Research, Llc | Detection of targeted sequence regions |
EP3638813A4 (fr) * | 2017-06-13 | 2021-06-02 | Genetics Research, LLC, D/B/A ZS Genetics, Inc. | Isolement d'acides nucléiques cibles |
JP2022511207A (ja) | 2018-12-05 | 2022-01-31 | イルミナ ケンブリッジ リミテッド | ブリッジ増幅によるクラスタ生成のための方法および組成物 |
JP2022513546A (ja) | 2018-12-18 | 2022-02-09 | イルミナ ケンブリッジ リミテッド | 単一表面プライマーを使用したペアエンドシーケンシングのための方法および組成物 |
CA3131514A1 (fr) * | 2019-02-25 | 2020-09-03 | Twist Bioscience Corporation | Compositions et procedes de sequencage de nouvelle generation |
CN111961711A (zh) * | 2020-08-31 | 2020-11-20 | 伯科生物科技有限公司 | 用于靶向测序的通用杂交增强剂及方法 |
WO2022125939A1 (fr) * | 2020-12-10 | 2022-06-16 | The United States Government | Méthodes de détection de cibles homogènes dans une population avec séquençage de nouvelle génération |
CN113293205A (zh) * | 2021-05-24 | 2021-08-24 | 深圳市真迈生物科技有限公司 | 测序方法 |
CN113981056A (zh) * | 2021-11-26 | 2022-01-28 | 广州达安基因股份有限公司 | 基于已知标签的内参进行高通量测序的方法 |
WO2023126457A1 (fr) | 2021-12-29 | 2023-07-06 | Illumina Cambridge Ltd. | Procédés de séquençage d'acide nucléique à l'aide d'amorces liées à une surface |
Family Cites Families (83)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
AU622426B2 (en) | 1987-12-11 | 1992-04-09 | Abbott Laboratories | Assay using template-dependent nucleic acid probe reorganization |
CA1341584C (fr) | 1988-04-06 | 2008-11-18 | Bruce Wallace | Methode d'amplification at de detection de sequences d'acides nucleiques |
AU3539089A (en) | 1988-04-08 | 1989-11-03 | Salk Institute For Biological Studies, The | Ligase-based amplification method |
US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
WO1989012696A1 (fr) | 1988-06-24 | 1989-12-28 | Amgen Inc. | Procede et reactifs de detection de sequences d'acides nucleiques |
ATE138106T1 (de) | 1988-07-20 | 1996-06-15 | David Segev | Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen |
US5185243A (en) | 1988-08-25 | 1993-02-09 | Syntex (U.S.A.) Inc. | Method for detection of specific nucleic acid sequences |
CA2044616A1 (fr) | 1989-10-26 | 1991-04-27 | Roger Y. Tsien | Sequencage de l'adn |
US5573907A (en) | 1990-01-26 | 1996-11-12 | Abbott Laboratories | Detecting and amplifying target nucleic acids using exonucleolytic activity |
ATE137269T1 (de) | 1990-01-26 | 1996-05-15 | Abbott Lab | Verbessertes verfahren zur amplifikation von nuklein säurezielsequenz, einsetzbar für die polymerase und ligasekettenreaktion |
US5223414A (en) | 1990-05-07 | 1993-06-29 | Sri International | Process for nucleic acid hybridization and amplification |
US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
WO1995021271A1 (fr) | 1994-02-07 | 1995-08-10 | Molecular Tool, Inc. | Analysetm d'elements genetiques induite par la ligase/polymerase de polymorphismes de mononucleotides et son utilisation dans des analyses genetiques |
WO1995025180A1 (fr) | 1994-03-16 | 1995-09-21 | Gen-Probe Incorporated | Amplification d'acide nucleique par deplacement de la souche isotherme |
US6232465B1 (en) | 1994-09-02 | 2001-05-15 | Andrew C. Hiatt | Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides |
US5872244A (en) | 1994-09-02 | 1999-02-16 | Andrew C. Hiatt | 3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds |
US5808045A (en) | 1994-09-02 | 1998-09-15 | Andrew C. Hiatt | Compositions for enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides |
US6214987B1 (en) | 1994-09-02 | 2001-04-10 | Andrew C. Hiatt | Compositions for enzyme catalyzed template-independent formation of phosphodiester bonds using protected nucleotides |
US5763594A (en) | 1994-09-02 | 1998-06-09 | Andrew C. Hiatt | 3' protected nucleotides for enzyme catalyzed template-independent creation of phosphodiester bonds |
US5990300A (en) | 1994-09-02 | 1999-11-23 | Andrew C. Hiatt | Enzyme catalyzed template-independent creation of phosphodiester bonds using protected nucleotides |
US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
ES2563643T3 (es) | 1997-04-01 | 2016-03-15 | Illumina Cambridge Limited | Método de secuenciación de ácido nucleico |
AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
US7955794B2 (en) | 2000-09-21 | 2011-06-07 | Illumina, Inc. | Multiplex nucleic acid reactions |
US7582420B2 (en) | 2001-07-12 | 2009-09-01 | Illumina, Inc. | Multiplex nucleic acid reactions |
US7611869B2 (en) | 2000-02-07 | 2009-11-03 | Illumina, Inc. | Multiplexed methylation detection methods |
CN100462433C (zh) | 2000-07-07 | 2009-02-18 | 维西根生物技术公司 | 实时序列测定 |
AU2002227156A1 (en) | 2000-12-01 | 2002-06-11 | Visigen Biotechnologies, Inc. | Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity |
AR031640A1 (es) | 2000-12-08 | 2003-09-24 | Applied Research Systems | Amplificacion isotermica de acidos nucleicos en un soporte solido |
US6849404B2 (en) | 2001-05-07 | 2005-02-01 | Bioneer Corporation | Polymerase chain reaction of DNA of which base sequence is completely unidentified |
GB0129012D0 (en) | 2001-12-04 | 2002-01-23 | Solexa Ltd | Labelled nucleotides |
US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
GB2395954A (en) | 2002-08-23 | 2004-06-09 | Solexa Ltd | Modified nucleotides |
EP1539979B1 (fr) | 2002-09-20 | 2008-11-19 | New England Biolabs, Inc. | Amplification dependant de l'helicase des acides nucleiques |
WO2004081183A2 (fr) | 2003-03-07 | 2004-09-23 | Rubicon Genomics, Inc. | Immortalisation d'adn in vitro et amplification genomique complete a l'aide de bibliotheques generees a partir d'adn fragmente de manière aleatoire |
JP2007525963A (ja) | 2003-06-20 | 2007-09-13 | イルミナ インコーポレイテッド | 全ゲノム増幅および遺伝型決定のための方法および組成物 |
GB0321306D0 (en) | 2003-09-11 | 2003-10-15 | Solexa Ltd | Modified polymerases for improved incorporation of nucleotide analogues |
EP2789383B1 (fr) | 2004-01-07 | 2023-05-03 | Illumina Cambridge Limited | Réseaux moléculaires |
US7476503B2 (en) | 2004-09-17 | 2009-01-13 | Pacific Biosciences Of California, Inc. | Apparatus and method for performing nucleic acid analysis |
WO2006064199A1 (fr) | 2004-12-13 | 2006-06-22 | Solexa Limited | Procede ameliore de detection de nucleotides |
JP4990886B2 (ja) | 2005-05-10 | 2012-08-01 | ソレックサ リミテッド | 改良ポリメラーゼ |
EP1910537A1 (fr) | 2005-06-06 | 2008-04-16 | 454 Life Sciences Corporation | Séquençage d'extrémités appariées |
GB0514910D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Method for sequencing a polynucleotide template |
GB0514936D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Preparation of templates for nucleic acid sequencing |
US7405281B2 (en) | 2005-09-29 | 2008-07-29 | Pacific Biosciences Of California, Inc. | Fluorescent nucleotide analogs and uses therefor |
GB0522310D0 (en) * | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
US20080009420A1 (en) | 2006-03-17 | 2008-01-10 | Schroth Gary P | Isothermal methods for creating clonal single molecule arrays |
WO2007123744A2 (fr) | 2006-03-31 | 2007-11-01 | Solexa, Inc. | Systèmes et procédés pour analyse de séquençage par synthèse |
USRE49362E1 (en) | 2006-05-18 | 2023-01-10 | Illumina Cambridge Limited | Dye compounds and the use of their labelled conjugates |
US7833716B2 (en) | 2006-06-06 | 2010-11-16 | Gen-Probe Incorporated | Tagged oligonucleotides and their use in nucleic acid amplification methods |
US8399188B2 (en) | 2006-09-28 | 2013-03-19 | Illumina, Inc. | Compositions and methods for nucleotide sequencing |
US7754429B2 (en) | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
US8343746B2 (en) | 2006-10-23 | 2013-01-01 | Pacific Biosciences Of California, Inc. | Polymerase enzymes and reagents for enhanced nucleic acid sequencing |
EP2121983A2 (fr) | 2007-02-02 | 2009-11-25 | Illumina Cambridge Limited | Procedes pour indexer des echantillons et sequencer de multiples matrices nucleotidiques |
WO2010003132A1 (fr) | 2008-07-02 | 2010-01-07 | Illumina Cambridge Ltd. | Utilisation de populations de billes dans la fabrication de matrices sur des surfaces |
US20100062494A1 (en) | 2008-08-08 | 2010-03-11 | President And Fellows Of Harvard College | Enzymatic oligonucleotide pre-adenylation |
CN102859003B (zh) | 2010-03-08 | 2014-07-30 | 达纳-法伯癌症研究院有限公司 | 使用参考封闭序列的全cold-pcr富集 |
US8778848B2 (en) | 2011-06-09 | 2014-07-15 | Illumina, Inc. | Patterned flow-cells useful for nucleic acid analysis |
US8778849B2 (en) | 2011-10-28 | 2014-07-15 | Illumina, Inc. | Microarray fabrication system and method |
EP2636427B1 (fr) | 2012-01-16 | 2019-02-27 | Greatbatch Ltd. | Isolateur de traversée hermétique élevée adapté pour une fixation latérale de conducteurs électriques sur le côté de fluide corporel d'un dispositif médical implantable actif |
WO2013112923A1 (fr) | 2012-01-26 | 2013-08-01 | Nugen Technologies, Inc. | Compositions et procédés pour l'enrichissement en séquence d'acide nucléique ciblée et la génération d'une banque à efficacité élevée |
ES2928691T3 (es) | 2012-05-21 | 2022-11-22 | Scripps Research Inst | Métodos de preparación de muestras |
US8895249B2 (en) | 2012-06-15 | 2014-11-25 | Illumina, Inc. | Kinetic exclusion amplification of nucleic acid libraries |
US9512422B2 (en) | 2013-02-26 | 2016-12-06 | Illumina, Inc. | Gel patterned surfaces |
US10174352B2 (en) | 2013-03-14 | 2019-01-08 | Aegea Biotechnologies, Inc. | Methods for amplification of nucleic acids on solid support |
US10421996B2 (en) | 2013-03-14 | 2019-09-24 | Illumina, Inc. | Modified polymerases for improved incorporation of nucleotide analogues |
ES2685549T3 (es) | 2013-03-15 | 2018-10-09 | Illumina Cambridge Limited | Nucleósidos o nucleótidos modificados |
CN105431554B (zh) | 2013-07-01 | 2019-02-15 | Illumina公司 | 无催化剂的表面官能化和聚合物接枝 |
RU2698125C2 (ru) | 2013-08-19 | 2019-08-22 | Эбботт Молекьюлар Инк. | Библиотеки для секвенирования нового поколения |
EP3066114B1 (fr) * | 2013-11-07 | 2019-11-13 | Agilent Technologies, Inc. | Pluralité d'adaptateurs de transposase destinés à des manipulations d'adn |
US9677132B2 (en) | 2014-01-16 | 2017-06-13 | Illumina, Inc. | Polynucleotide modification on solid support |
PL3161154T3 (pl) | 2014-06-27 | 2020-10-19 | Illumina, Inc. | Zmodyfikowane polimerazy do ulepszonego włączania analogów nukleotydów |
CN107002051A (zh) | 2014-09-30 | 2017-08-01 | 亿明达股份有限公司 | 用于核苷酸类似物的改善的掺入的经修饰的聚合酶 |
CA2965578C (fr) | 2014-10-31 | 2024-03-19 | Illumina Cambridge Limited | Polymeres et revetements copolymeres d'adn |
RU2761432C2 (ru) | 2015-02-10 | 2021-12-08 | Иллюмина, Инк. | Способ и композиция для анализа клеточных компонентов |
EP3356526B1 (fr) | 2015-09-30 | 2021-08-25 | The General Hospital Corporation | Rapport in vitro complet d'événements de clivage par séquençage (circle-seq) |
WO2018197950A1 (fr) | 2017-04-23 | 2018-11-01 | Illumina Cambridge Limited | Compositions et procédés pour améliorer l'identification d'échantillons dans des bibliothèques d'acides nucléiques indexées |
ES2893528T3 (es) | 2017-04-23 | 2022-02-09 | Illumina Cambridge Ltd | Composiciones y métodos para mejorar la identificación de muestras en colecciones de ácidos nucleicos indexadas |
WO2018200386A1 (fr) | 2017-04-23 | 2018-11-01 | Illumina, Inc. | Compositions et procédés pour améliorer l'identification d'échantillons dans des bibliothèques d'acides nucléiques indexés |
EP3913053A1 (fr) | 2017-04-23 | 2021-11-24 | Illumina Cambridge Limited | Compositions et procédés permettant d'améliorer l'identification d'échantillons dans des bibliothèques d'acides nucléiques indexés |
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2018
- 2018-04-23 WO PCT/US2018/028881 patent/WO2018200386A1/fr unknown
- 2018-04-23 FI FIEP21157377.9T patent/FI3842545T3/fi active
- 2018-04-23 CN CN201880040485.3A patent/CN110770353A/zh active Pending
- 2018-04-23 AU AU2018260633A patent/AU2018260633B2/en active Active
- 2018-04-23 CA CA3059952A patent/CA3059952C/fr active Active
- 2018-04-23 EP EP18723275.6A patent/EP3615691B1/fr active Active
- 2018-04-23 US US15/959,984 patent/US10934584B2/en active Active
- 2018-04-23 ES ES18723275T patent/ES2882608T3/es active Active
- 2018-04-23 EP EP21157377.9A patent/EP3842545B1/fr active Active
- 2018-04-23 SG SG11201909394P patent/SG11201909394PA/en unknown
- 2018-04-23 ES ES21157377T patent/ES2937929T3/es active Active
- 2018-04-23 DK DK18723275.6T patent/DK3615691T3/da active
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2021
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AU2021203361B2 (en) | 2024-05-16 |
EP3615691A1 (fr) | 2020-03-04 |
CN110770353A (zh) | 2020-02-07 |
FI3842545T3 (fi) | 2023-01-31 |
ES2882608T3 (es) | 2021-12-02 |
CA3059952C (fr) | 2023-04-18 |
US10934584B2 (en) | 2021-03-02 |
ES2937929T3 (es) | 2023-04-03 |
AU2018260633B2 (en) | 2021-04-15 |
DK3615691T3 (da) | 2021-07-26 |
US20210172014A1 (en) | 2021-06-10 |
EP3842545A1 (fr) | 2021-06-30 |
AU2024202607A1 (en) | 2024-05-09 |
WO2018200386A8 (fr) | 2019-02-14 |
EP3842545B1 (fr) | 2022-11-30 |
AU2021203361A1 (en) | 2021-06-24 |
EP3615691B1 (fr) | 2021-05-26 |
US20180305752A1 (en) | 2018-10-25 |
CA3059952A1 (fr) | 2018-11-01 |
WO2018200386A1 (fr) | 2018-11-01 |
AU2018260633A1 (en) | 2019-10-31 |
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