SG11201907927SA - Binding molecules that specifically bind to tau - Google Patents
Binding molecules that specifically bind to tauInfo
- Publication number
- SG11201907927SA SG11201907927SA SG11201907927SA SG11201907927SA SG 11201907927S A SG11201907927S A SG 11201907927SA SG 11201907927S A SG11201907927S A SG 11201907927SA SG 11201907927S A SG11201907927S A SG 11201907927SA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- archimedesweg
- leiden
- binding molecules
- pct
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP17163425 | 2017-03-28 | ||
PCT/EP2018/057770 WO2018178077A1 (en) | 2017-03-28 | 2018-03-27 | Binding molecules that specifically bind to tau |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201907927SA true SG11201907927SA (en) | 2019-10-30 |
Family
ID=58448491
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201907927S SG11201907927SA (en) | 2017-03-28 | 2018-03-27 | Binding molecules that specifically bind to tau |
Country Status (10)
Country | Link |
---|---|
US (1) | US11028157B2 (ru) |
EP (1) | EP3601335A1 (ru) |
JP (1) | JP7109467B2 (ru) |
KR (1) | KR20190133191A (ru) |
CN (1) | CN110418804A (ru) |
AU (1) | AU2018241857A1 (ru) |
CA (1) | CA3056517A1 (ru) |
EA (1) | EA201992281A1 (ru) |
SG (1) | SG11201907927SA (ru) |
WO (1) | WO2018178077A1 (ru) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2970453B1 (en) | 2013-03-13 | 2019-12-04 | Prothena Biosciences Limited | Tau immunotherapy |
WO2017191559A1 (en) | 2016-05-02 | 2017-11-09 | Prothena Biosciences Limited | Tau immunotherapy |
UA124148C2 (uk) | 2016-05-02 | 2021-07-28 | Протена Біосайенсіс Лімітед | Антитіла, що розпізнають тау |
WO2018152359A1 (en) | 2017-02-17 | 2018-08-23 | Denali Therapeutics Inc. | Anti-tau antibodies and methods of use thereof |
BR112019022906A2 (pt) | 2017-05-02 | 2020-05-26 | Prothena Biosciences Limited | Anticorpos que reconhecem tau |
SG11202108414UA (en) | 2019-03-03 | 2021-08-30 | Prothena Biosciences Ltd | Antibodies recognizing tau |
GB201909393D0 (en) | 2019-06-28 | 2019-08-14 | Gen2 Neuroscience Ltd | Tau epitope and binding molecules |
WO2023092004A1 (en) | 2021-11-17 | 2023-05-25 | Voyager Therapeutics, Inc. | Compositions and methods for the treatment of tau-related disorders |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60043273D1 (de) | 1999-04-15 | 2009-12-17 | Crucell Holland Bv | Verwendung von Rekombinanten Proteinen in Menschlichen Zellen |
ES2686550T3 (es) * | 2010-10-11 | 2018-10-18 | Biogen International Neuroscience Gmbh | Anticuerpos anti-tau humanos |
EP2701743A4 (en) | 2011-04-27 | 2015-08-19 | Univ Northwestern | SELECTIVE ANTIBODIES FOR TAU PATHOLOGICAL DIMERS AND PRE-FIBRILLARY TAU PATHOLOGICAL OLIGOMERS AND THEIR USE IN THE TREATMENT, DIAGNOSIS AND MONITORING OF TAUOPATHIES |
UA115657C2 (uk) | 2011-09-19 | 2017-12-11 | Аксон Ньюросайєнс Сє | Виділене антитіло, яке зв'язується з одним або декількома епітопами тау, фармацевтична композиція, що його містить, спосіб лікування та спосіб діагностики хвороби альцгеймера на основі виділеного антитіла |
ZA201608812B (en) * | 2014-06-26 | 2019-08-28 | Janssen Vaccines & Prevention Bv | Antibodies and antigen-binding fragments that specifically bind to microtubule-associated protein tau |
KR20170023151A (ko) * | 2014-06-26 | 2017-03-02 | 얀센 백신스 앤드 프리벤션 비.브이. | 미세소관-연관 단백질 타우에 특이적으로 결합하는 항체 및 항원-결합 단편 |
RS61431B1 (sr) | 2014-11-19 | 2021-03-31 | Axon Neuroscience Se | Humanizovana antitela na tau u alchajmerovoj bolesti |
-
2018
- 2018-03-27 KR KR1020197030544A patent/KR20190133191A/ko unknown
- 2018-03-27 EA EA201992281A patent/EA201992281A1/ru unknown
- 2018-03-27 EP EP18715587.4A patent/EP3601335A1/en not_active Withdrawn
- 2018-03-27 US US16/497,916 patent/US11028157B2/en active Active
- 2018-03-27 WO PCT/EP2018/057770 patent/WO2018178077A1/en unknown
- 2018-03-27 CA CA3056517A patent/CA3056517A1/en active Pending
- 2018-03-27 SG SG11201907927S patent/SG11201907927SA/en unknown
- 2018-03-27 AU AU2018241857A patent/AU2018241857A1/en not_active Abandoned
- 2018-03-27 JP JP2019552923A patent/JP7109467B2/ja active Active
- 2018-03-27 CN CN201880015336.1A patent/CN110418804A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
JP2020511976A (ja) | 2020-04-23 |
EA201992281A1 (ru) | 2020-02-13 |
AU2018241857A1 (en) | 2019-09-19 |
US11028157B2 (en) | 2021-06-08 |
JP7109467B2 (ja) | 2022-07-29 |
KR20190133191A (ko) | 2019-12-02 |
EP3601335A1 (en) | 2020-02-05 |
CN110418804A (zh) | 2019-11-05 |
WO2018178077A1 (en) | 2018-10-04 |
US20210122810A1 (en) | 2021-04-29 |
CA3056517A1 (en) | 2018-10-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SG11201907927SA (en) | Binding molecules that specifically bind to tau | |
SG11201811003PA (en) | Anti-pd-l1 antibodies and uses thereof | |
SG11201811432WA (en) | Rna for cancer therapy | |
SG11201811431VA (en) | Multispecific antibodies against cd40 and cd137 | |
SG11201808622SA (en) | Chimeric receptors to flt3 and methods of use thereof | |
SG11201807912SA (en) | Vaccine against rsv | |
SG11201807401RA (en) | Therapeutic membrane vesicles | |
SG11201908919XA (en) | Combination therapies targeting pd-1, tim-3, and lag-3 | |
SG11201810927QA (en) | Pd-l1-specific antibodies and methods of using the same | |
SG11201407580YA (en) | Composition comprising two antibodies engineered to have reduced and increased effector function | |
SG11201408780XA (en) | Optimization of antibodies that bind lymphocyte activation gene-3 (lag-3), and uses thereof | |
SG11201403106SA (en) | Anti-phf-tau antibodies and their uses | |
SG11201908325PA (en) | Process for the preparation of glucuronide drug-linkers and intermediates thereof | |
SG11201809374VA (en) | Cd40l-fc fusion polypeptides and methods of use thereof | |
SG11201807827VA (en) | Process for the preparation of pegylated drug-linkers and intermediates thereof | |
SG11201909680UA (en) | Phenyl-2-hydroxy-acetylamino-2-methyl-phenyl compounds | |
SG11201807523PA (en) | Ilt7 binding molecules and methods of using the same | |
SG11201804704PA (en) | Compositions and methods for decreasing tau expression | |
SG11201803692PA (en) | Anti-5t4 antibodies and antibody-drug conjugates | |
SG11201907208XA (en) | Radiolabeled anti-lag3 antibodies for immuno-pet imaging | |
SG11201809882XA (en) | Pharmaceutical combinations for treating cancer | |
SG11201810801QA (en) | Brain delivery protein | |
SG11201807062RA (en) | Anti-tnfalpha-antibodies and functional fragments thereof | |
SG11201806622PA (en) | Egfl6 specific monoclonal antibodies and methods of their use | |
SG11201900132QA (en) | Selecting neoepitopes as disease-specific targets for therapy with enhanced efficacy |