SG11201903259XA - Microfluidic system - Google Patents
Microfluidic systemInfo
- Publication number
- SG11201903259XA SG11201903259XA SG11201903259XA SG11201903259XA SG11201903259XA SG 11201903259X A SG11201903259X A SG 11201903259XA SG 11201903259X A SG11201903259X A SG 11201903259XA SG 11201903259X A SG11201903259X A SG 11201903259XA SG 11201903259X A SG11201903259X A SG 11201903259XA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- reservoir
- pct
- particles
- microfluidic system
- Prior art date
Links
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0652—Sorting or classification of particles or molecules
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/047—Additional chamber, reservoir
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0663—Whole sensors
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0883—Serpentine channels
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
- B01L2300/1822—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
- B01L2300/185—Means for temperature control using fluid heat transfer medium using a liquid as fluid
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1894—Cooling means; Cryo cooling
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1#111011110111010101111101111101001111111111111111111111111111111111111111111 Organization International Bureau (10) International Publication Number (43) International Publication Date .....0-\" WO 2018/073760 Al 26 April 2018 (26.04.2018) W I PO I PCT (51) International Patent Classification: (74) Agent: MANGINI, Simone et al.; Studio Torta S.p.A., Via BOIL 3/00 (2006.01) Viotti, 9, 10121 Torino (IT). (21) International Application Number: (81) Designated States (unless otherwise indicated, for every PCT/IB2017/056473 kind of national protection available): AE, AG, AL, AM, (22) International Filing Date: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, 18 October 2017 (18.10.2017) CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (25) Filing Language: Italian HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, (26) Publication Language: English KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, (30) Priority Data: OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, 102016000104601 18 October 2016 (18.10.2016) IT SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (71) Applicant: MENARINI SILICON BIOSYSTEMS S.P.A. [IT/IT]; Via Giuseppe di Vittorio, 21B/3, 40013 Cas- (84) Designated States (unless otherwise indicated, for every tel Maggiore (IT). kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (72) Inventors: MEDORO, Gianni; Via della Badia, 9, 40033 UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, Casalecchio Di Reno (IT). CALANCA, Alex; Via Statale Nord, 134, 41037 Mirandola (IT). TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, = (54) Title: MICROFLUIDIC SYSTEM = = 1 = = 20' 1 4 .) \ 20.., E = _ t 19 .-, = \ ( 30 — , 41 Am. 23 s 21 = 18 11 1) 42 „ 16 = - -a-22 = _ j--------15 = 29 = = 0, 1 32- - -.34 40 = 4D 33 = 1 O 7 38 = s ) 37 30 ... 6 ( \ • 35 Fial 1-1 39' 11 © I N V; (57) : A microfluidic system (1) for the isolation of particles of at least one given type belonging to a sample and comprising M a separation unit (3), which is designed to transfer the particles of given type from a main chamber (4) to a recovery chamber (5) in a C substantially selective manner with respect to further particles of the sample; at least one first reservoir (6), which is designed to contain ---. a liquid and is fluidically connected to the separation unit (3); and a regulating assembly (13), which comprises at least a first regulating GCdevice (14) having a first heat transfer element (15) arranged at the first reservoir (6) to adjust the temperature of the first reservoir 1-1 © (6), in particular to absorb heat from the reservoir (6). ei C [Continued on next page] WO 2018/073760 Al MIDEDIMOHNIIME101111111100MINIIMOVOIS MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT102016000104601A IT201600104601A1 (en) | 2016-10-18 | 2016-10-18 | MICROFLUID SYSTEM |
PCT/IB2017/056473 WO2018073760A1 (en) | 2016-10-18 | 2017-10-18 | Microfluidic system |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201903259XA true SG11201903259XA (en) | 2019-05-30 |
Family
ID=58010211
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201903259XA SG11201903259XA (en) | 2016-10-18 | 2017-10-18 | Microfluidic system |
Country Status (17)
Country | Link |
---|---|
US (1) | US11077437B2 (en) |
EP (1) | EP3528948B1 (en) |
JP (1) | JP7079788B2 (en) |
KR (1) | KR102676273B1 (en) |
CN (1) | CN109843439B (en) |
AU (1) | AU2017344470B2 (en) |
CA (1) | CA3039856C (en) |
DK (1) | DK3528948T3 (en) |
ES (1) | ES2809166T3 (en) |
HU (1) | HUE052887T2 (en) |
IL (1) | IL266141B (en) |
IT (1) | IT201600104601A1 (en) |
PT (1) | PT3528948T (en) |
SA (1) | SA519401589B1 (en) |
SG (1) | SG11201903259XA (en) |
SI (1) | SI3528948T1 (en) |
WO (1) | WO2018073760A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
SG10202103867PA (en) * | 2016-10-18 | 2021-05-28 | Menarini Silicon Biosystems Spa | Microfluidic device, microfluidic system and method for the isolation of particles |
US20210039102A1 (en) * | 2018-02-01 | 2021-02-11 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods and systems for designing and producing nano-structured optical devices |
CN113301974A (en) * | 2019-01-25 | 2021-08-24 | 瑞泽恩制药公司 | On-line chromatography and electrospray ionization mass spectrometer |
US20240050957A1 (en) | 2020-12-17 | 2024-02-15 | Totalenergies Onetech | System for controlling the temperature of a microfluidic chip and a microfluidic apparatus for monitoring a substance in a microfluidic chip including such system |
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IT1309430B1 (en) | 1999-05-18 | 2002-01-23 | Guerrieri Roberto | METHOD AND APPARATUS FOR HANDLING PARTICLES BY MEANS OF ELECTROPHORESIS |
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US6459581B1 (en) * | 2000-12-19 | 2002-10-01 | Harris Corporation | Electronic device using evaporative micro-cooling and associated methods |
CA2564211C (en) * | 2004-01-26 | 2010-08-03 | President And Fellows Of Harvard College | Fluid delivery system and method |
CN101095384A (en) * | 2004-12-28 | 2007-12-26 | 加利福尼亚州技术学院 | Fluidic pump for heat management |
CN2767978Y (en) * | 2005-01-13 | 2006-03-29 | 中国电子科技集团公司第十三研究所 | Minitype temperature sensor with nanometer scale |
JP4829252B2 (en) * | 2005-01-25 | 2011-12-07 | オシロジー リミテッド ライアビリティ カンパニー | Temperature controller for microfluidic samples with different heat capacities |
CN100491931C (en) * | 2005-04-14 | 2009-05-27 | 中国科学院电工研究所 | Flow detecting device |
KR20060111143A (en) * | 2005-04-22 | 2006-10-26 | 한국표준과학연구원 | Apparatus for separating particles using optical trapping |
ITBO20050481A1 (en) | 2005-07-19 | 2007-01-20 | Silicon Biosystems S R L | METHOD AND APPARATUS FOR THE HANDLING AND / OR IDENTIFICATION OF PARTICLES |
JP4877710B2 (en) * | 2005-08-01 | 2012-02-15 | 大日本スクリーン製造株式会社 | Liquid processing apparatus and liquid supply method |
ITBO20050643A1 (en) | 2005-10-24 | 2007-04-25 | Si Bio S R L | METHOD AND APPARATUS FOR HANDLING PARTICLES IN CONDUCTIVE SOLUTIONS |
KR20090040329A (en) | 2006-07-20 | 2009-04-23 | 퓨리티 에이비 | Device for purification of a liquid |
KR20100028526A (en) | 2007-02-05 | 2010-03-12 | 마이크로칩 바이오테크놀로지스, 인크. | Microfluidic and nanofluidic devices, systems, and applications |
JP5859203B2 (en) * | 2007-07-23 | 2016-02-10 | クロンデイアグ・ゲーエムベーハー | Assay |
FI20085299A0 (en) * | 2008-04-10 | 2008-04-10 | Valtion Teknillinen | Microfluidic chip devices and their use |
WO2010072790A1 (en) * | 2008-12-23 | 2010-07-01 | Stmicroelectronics S.R.L. | Method for detecting the presence of liquids in a microfluidic device, detecting apparatus and corresponding microfluidic device |
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ITBO20090155A1 (en) | 2009-03-17 | 2010-09-18 | Silicon Biosystems Spa | METHOD FOR INSULATING PARTICLES |
ITBO20090154A1 (en) | 2009-03-17 | 2010-09-18 | Silicon Biosystems Spa | MICROFLUID SYSTEM |
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CN201600153U (en) * | 2010-02-08 | 2010-10-06 | 浙江小桥流水环境科技有限公司 | Mini flow switch and sensor thereof |
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2016
- 2016-10-18 IT IT102016000104601A patent/IT201600104601A1/en unknown
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2017
- 2017-10-18 US US16/342,940 patent/US11077437B2/en active Active
- 2017-10-18 SG SG11201903259XA patent/SG11201903259XA/en unknown
- 2017-10-18 WO PCT/IB2017/056473 patent/WO2018073760A1/en unknown
- 2017-10-18 SI SI201730414T patent/SI3528948T1/en unknown
- 2017-10-18 EP EP17800613.6A patent/EP3528948B1/en active Active
- 2017-10-18 CN CN201780064746.0A patent/CN109843439B/en active Active
- 2017-10-18 JP JP2019541902A patent/JP7079788B2/en active Active
- 2017-10-18 HU HUE17800613A patent/HUE052887T2/en unknown
- 2017-10-18 ES ES17800613T patent/ES2809166T3/en active Active
- 2017-10-18 PT PT178006136T patent/PT3528948T/en unknown
- 2017-10-18 DK DK17800613.6T patent/DK3528948T3/en active
- 2017-10-18 CA CA3039856A patent/CA3039856C/en active Active
- 2017-10-18 KR KR1020197013715A patent/KR102676273B1/en active IP Right Grant
- 2017-10-18 AU AU2017344470A patent/AU2017344470B2/en active Active
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2019
- 2019-04-16 SA SA519401589A patent/SA519401589B1/en unknown
- 2019-04-18 IL IL266141A patent/IL266141B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
IL266141A (en) | 2019-06-30 |
CN109843439A (en) | 2019-06-04 |
EP3528948B1 (en) | 2020-07-22 |
US11077437B2 (en) | 2021-08-03 |
WO2018073760A1 (en) | 2018-04-26 |
CA3039856A1 (en) | 2018-04-26 |
KR20190096963A (en) | 2019-08-20 |
JP2020500107A (en) | 2020-01-09 |
ES2809166T3 (en) | 2021-03-03 |
CA3039856C (en) | 2024-06-11 |
IL266141B (en) | 2020-11-30 |
AU2017344470B2 (en) | 2022-09-22 |
CN109843439B (en) | 2022-12-13 |
EP3528948A1 (en) | 2019-08-28 |
SA519401589B1 (en) | 2022-05-08 |
AU2017344470A1 (en) | 2019-05-02 |
KR102676273B1 (en) | 2024-06-18 |
IT201600104601A1 (en) | 2018-04-18 |
JP7079788B2 (en) | 2022-06-02 |
SI3528948T1 (en) | 2020-12-31 |
PT3528948T (en) | 2020-08-05 |
HUE052887T2 (en) | 2021-05-28 |
DK3528948T3 (en) | 2020-08-31 |
US20200055043A1 (en) | 2020-02-20 |
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