SG11201901184QA - Manipulated immunoregulatory element and immunity altered thereby - Google Patents
Manipulated immunoregulatory element and immunity altered therebyInfo
- Publication number
- SG11201901184QA SG11201901184QA SG11201901184QA SG11201901184QA SG11201901184QA SG 11201901184Q A SG11201901184Q A SG 11201901184QA SG 11201901184Q A SG11201901184Q A SG 11201901184QA SG 11201901184Q A SG11201901184Q A SG 11201901184QA SG 11201901184Q A SG11201901184Q A SG 11201901184QA
- Authority
- SG
- Singapore
- Prior art keywords
- manipulated
- altered
- immunoregulatory
- immunity
- immune system
- Prior art date
Links
- 230000004957 immunoregulator effect Effects 0.000 title abstract 4
- 230000036039 immunity Effects 0.000 title abstract 2
- 210000000987 immune system Anatomy 0.000 abstract 3
- 102100022089 Acyl-[acyl-carrier-protein] hydrolase Human genes 0.000 abstract 1
- 101000964894 Bos taurus 14-3-3 protein zeta/delta Proteins 0.000 abstract 1
- 108010021064 CTLA-4 Antigen Proteins 0.000 abstract 1
- 102000008203 CTLA-4 Antigen Human genes 0.000 abstract 1
- 229940045513 CTLA4 antagonist Drugs 0.000 abstract 1
- -1 DGKα Proteins 0.000 abstract 1
- 101000824278 Homo sapiens Acyl-[acyl-carrier-protein] hydrolase Proteins 0.000 abstract 1
- 101001025967 Homo sapiens Lysine-specific demethylase 6A Proteins 0.000 abstract 1
- 101000653374 Homo sapiens Methylcytosine dioxygenase TET2 Proteins 0.000 abstract 1
- 101000761581 Homo sapiens Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform Proteins 0.000 abstract 1
- 101000611023 Homo sapiens Tumor necrosis factor receptor superfamily member 6 Proteins 0.000 abstract 1
- 102100037462 Lysine-specific demethylase 6A Human genes 0.000 abstract 1
- 102100030803 Methylcytosine dioxygenase TET2 Human genes 0.000 abstract 1
- 102100034925 P-selectin glycoprotein ligand 1 Human genes 0.000 abstract 1
- 101710137390 P-selectin glycoprotein ligand 1 Proteins 0.000 abstract 1
- 102100040678 Programmed cell death protein 1 Human genes 0.000 abstract 1
- 101710089372 Programmed cell death protein 1 Proteins 0.000 abstract 1
- 102100024927 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform Human genes 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0016—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the nucleic acid is delivered as a 'naked' nucleic acid, i.e. not combined with an entity such as a cationic lipid
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- C07K14/70503—Immunoglobulin superfamily
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- Animal Behavior & Ethology (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020160103308 | 2016-08-12 | ||
US201762502822P | 2017-05-08 | 2017-05-08 | |
PCT/KR2017/008835 WO2018030874A1 (ko) | 2016-08-12 | 2017-08-14 | 조작된 면역조절요소 및 이에 의해 변형된 면역 활성 |
Publications (1)
Publication Number | Publication Date |
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SG11201901184QA true SG11201901184QA (en) | 2019-03-28 |
Family
ID=65438099
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201901184QA SG11201901184QA (en) | 2016-08-12 | 2017-08-14 | Manipulated immunoregulatory element and immunity altered thereby |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP3498846A4 (ja) |
JP (2) | JP7215808B2 (ja) |
KR (1) | KR102276371B1 (ja) |
CN (1) | CN109844118A (ja) |
AU (1) | AU2017308473B2 (ja) |
BR (1) | BR112019002779A2 (ja) |
CA (1) | CA3033736C (ja) |
RU (2) | RU2022103870A (ja) |
SG (1) | SG11201901184QA (ja) |
Families Citing this family (11)
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US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
EP3092049A1 (en) | 2014-01-08 | 2016-11-16 | Flodesign Sonics Inc. | Acoustophoresis device with dual acoustophoretic chamber |
US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
JP7235391B2 (ja) * | 2017-05-08 | 2023-03-08 | ツールゲン インコーポレイテッド | 人工的に操作された免疫細胞 |
SG11201913852RA (en) * | 2017-07-07 | 2020-01-30 | Toolgen Inc | Target-specific crispr mutant |
WO2019178420A1 (en) * | 2018-03-15 | 2019-09-19 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
CN111321171A (zh) * | 2018-12-14 | 2020-06-23 | 江苏集萃药康生物科技有限公司 | 一种应用CRISPR/Cas9介导ES打靶技术制备基因打靶动物模型的方法 |
CN110373385A (zh) * | 2019-07-12 | 2019-10-25 | 赛德特生物科技开发有限公司 | 改善神经细胞功能的免疫细胞培养基及其制备方法与应用 |
CN114807044B (zh) * | 2021-04-30 | 2023-09-08 | 四川大学华西医院 | 一种具有高nkt细胞比例的car-cik细胞制备方法及应用 |
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US20050244851A1 (en) * | 2004-01-13 | 2005-11-03 | Affymetrix, Inc. | Methods of analysis of alternative splicing in human |
US7901882B2 (en) * | 2006-03-31 | 2011-03-08 | Affymetrix, Inc. | Analysis of methylation using nucleic acid arrays |
CN102333277B (zh) | 2011-07-29 | 2014-08-06 | 上海合合信息科技发展有限公司 | 结合地理位置信息和蓝牙技术的电子名片传递方法及系统 |
WO2014039513A2 (en) * | 2012-09-04 | 2014-03-13 | The Trustees Of The University Of Pennsylvania | Inhibition of diacylglycerol kinase to augment adoptive t cell transfer |
JP6401704B2 (ja) * | 2012-10-10 | 2018-10-10 | サンガモ セラピューティクス, インコーポレイテッド | T細胞を修飾する化合物およびその使用 |
WO2014093595A1 (en) * | 2012-12-12 | 2014-06-19 | The Broad Institute, Inc. | Crispr-cas component systems, methods and compositions for sequence manipulation |
US11311575B2 (en) * | 2013-05-13 | 2022-04-26 | Cellectis | Methods for engineering highly active T cell for immunotherapy |
ES2883131T3 (es) * | 2013-05-29 | 2021-12-07 | Cellectis | Métodos para la modificación de células T para inmunoterapia utilizando el sistema de nucleasa CAS guiado por ARN |
JP6779785B2 (ja) * | 2013-12-19 | 2020-11-04 | ノバルティス アーゲー | ヒトメソテリンキメラ抗原受容体およびその使用 |
CN106536721B (zh) * | 2014-08-06 | 2020-12-04 | 车医科学大学校产学协力团 | 核酸酶介导的编辑编码hla的基因所产生的免疫相容性细胞 |
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CN109844118A (zh) | 2019-06-04 |
BR112019002779A2 (pt) | 2019-05-14 |
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RU2767206C2 (ru) | 2022-03-16 |
AU2017308473A1 (en) | 2019-02-28 |
AU2017308473B2 (en) | 2021-08-19 |
RU2022103870A (ru) | 2022-03-04 |
RU2019106669A (ru) | 2020-09-14 |
EP3498846A1 (en) | 2019-06-19 |
KR102276371B1 (ko) | 2021-07-12 |
EP3498846A4 (en) | 2020-03-11 |
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