SG11201811706RA - Process for the preparation of microcapsules - Google Patents

Process for the preparation of microcapsules

Info

Publication number
SG11201811706RA
SG11201811706RA SG11201811706RA SG11201811706RA SG11201811706RA SG 11201811706R A SG11201811706R A SG 11201811706RA SG 11201811706R A SG11201811706R A SG 11201811706RA SG 11201811706R A SG11201811706R A SG 11201811706RA SG 11201811706R A SG11201811706R A SG 11201811706RA
Authority
SG
Singapore
Prior art keywords
international
firmenich
geneva
route des
microcapsules
Prior art date
Application number
SG11201811706RA
Other languages
English (en)
Inventor
Elie Florence Vigouroux
Sonia Godefroy
Murray Osborne
Original Assignee
Firmenich & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Firmenich & Cie filed Critical Firmenich & Cie
Publication of SG11201811706RA publication Critical patent/SG11201811706RA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/37—Polymers
    • C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28—Microcapsules or nanocapsules
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
    • A23L27/72—Encapsulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/87—Polyurethanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q13/00—Formulations or additives for perfume preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • B01J13/14—Polymerisation; cross-linking
    • B01J13/16—Interfacial polymerisation
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D17/00—Detergent materials or soaps characterised by their shape or physical properties
    • C11D17/0039—Coated compositions or coated components in the compositions, (micro)capsules
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/37—Polymers
    • C11D3/3703—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C11D3/3726—Polyurethanes
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/50—Perfumes
    • C11D3/502—Protected perfumes
    • C11D3/505—Protected perfumes encapsulated or adsorbed on a carrier, e.g. zeolite or clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures
    • A61K2800/594—Mixtures of polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/20—After-treatment of capsule walls, e.g. hardening
    • B01J13/206—Hardening; drying

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Agronomy & Crop Science (AREA)
  • Nutrition Science (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Fats And Perfumes (AREA)
  • Cosmetics (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Detergent Compositions (AREA)
  • Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
  • Medicinal Preparation (AREA)
SG11201811706RA 2016-07-27 2017-07-26 Process for the preparation of microcapsules SG11201811706RA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16181447 2016-07-27
PCT/EP2017/068904 WO2018019894A1 (en) 2016-07-27 2017-07-26 Process for the preparation of microcapsules

Publications (1)

Publication Number Publication Date
SG11201811706RA true SG11201811706RA (en) 2019-02-27

Family

ID=56555235

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201811706RA SG11201811706RA (en) 2016-07-27 2017-07-26 Process for the preparation of microcapsules

Country Status (7)

Country Link
US (1) US11471397B2 (zh)
EP (1) EP3491110A1 (zh)
JP (1) JP7416620B2 (zh)
CN (1) CN109477041A (zh)
MX (1) MX2019000609A (zh)
SG (1) SG11201811706RA (zh)
WO (1) WO2018019894A1 (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9974720B2 (en) 2015-12-30 2018-05-22 International Flavors & Fragrances Inc. Compositions containing microcapsules coated with deposition proteins
SG11202004654RA (en) * 2018-01-26 2020-06-29 Firmenich & Cie Hair coloring composition comprising microcapsules
CN111526939B (zh) * 2018-03-19 2023-06-09 弗门尼舍有限公司 微胶囊的制备方法
EP3897524A4 (en) * 2018-12-18 2023-04-26 International Flavors & Fragrances Inc. PROTEIN MICROCAPSULES AND THEIR PREPARATION METHOD
EP4045179A1 (en) 2019-10-16 2022-08-24 Symrise AG Polyurea microcapsules and liquid surfactant systems containing them
WO2021091046A1 (ko) * 2019-11-05 2021-05-14 주식회사 엘지생활건강 자연 분해성 마이크로캡슐 및 이의 제조방법
CN111764175A (zh) * 2020-07-30 2020-10-13 上海常嘉纺织科技有限公司 纺织品香味处理微胶囊的制备方法
CN115551630A (zh) * 2021-02-09 2022-12-30 弗门尼舍有限公司 包含再生生物聚合物的混合微胶囊
US20240148617A1 (en) * 2021-03-31 2024-05-09 Firmenich Sa Coated core-shell microcapsules
AU2022399431A1 (en) 2021-12-03 2024-05-30 International Flavors & Fragrances Inc. Aqueous fabric conditioner compositions with high performance fragrances
WO2023168069A1 (en) 2022-03-04 2023-09-07 International Flavors & Fragrances Inc. Fragrance compositions for sleep improvement
WO2023172542A1 (en) 2022-03-07 2023-09-14 International Flavors & Fragrances Inc. Fragrance-containing granules
WO2024035547A1 (en) 2022-08-09 2024-02-15 International Flavors & Fragrances Inc. Fragrance-containing granules

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577515A (en) * 1963-12-13 1971-05-04 Pennwalt Corp Encapsulation by interfacial polycondensation
JPS4939579A (zh) * 1972-08-21 1974-04-13
GB1538075A (en) * 1975-03-24 1979-01-10 Champion Paper Co Ltd Formation of microcapsules by interfacial cross-linking and microcapsules produced thereby
US4145184A (en) * 1975-11-28 1979-03-20 The Procter & Gamble Company Detergent composition containing encapsulated perfume
DE3635821A1 (de) * 1986-10-22 1988-04-28 Bayer Ag Mikrokapseln mit verbesserten waenden
JPH03173565A (ja) * 1989-11-30 1991-07-26 Kanzaki Paper Mfg Co Ltd 香料内蔵噴霧器
US5225118A (en) * 1990-08-15 1993-07-06 Boise Cascade Corporation Process for manufacturing polyurea microcapsules and product therefrom
JP2800609B2 (ja) * 1992-12-02 1998-09-21 富士ゼロックス株式会社 カプセルトナーおよびその製造方法
WO1994029603A1 (en) * 1993-06-16 1994-12-22 Korea Research Institute Of Chemical Technology Polymer sealant microencapsulated by polyurethane reaction and its binder solution
JPH0859770A (ja) * 1994-08-15 1996-03-05 Dainippon Ink & Chem Inc ポリウレタンポリ尿素架橋微粒子分散体及びその製造方法
IL127116A (en) 1996-05-23 2001-06-14 Zeneca Ltd Process for preparing microcapsules
JP3173565B2 (ja) 1996-06-20 2001-06-04 日本電気株式会社 Ｃｄｍａシステムにおけるアクセス規制装置
KR20060031602A (ko) * 2003-05-11 2006-04-12 벤 구리온 유니버시티 오브 더 네게브 리서치 앤드 디벨로프먼트오서리티 캡슐에 둘러싸인 에센스 오일
US9816059B2 (en) 2009-09-18 2017-11-14 International Flavors & Fragrances Stabilized capsule compositions
EP2579976B1 (en) 2010-06-11 2017-08-09 Firmenich SA Process for preparing polyurea microcapsules
JP6012724B2 (ja) * 2011-06-28 2016-10-25 フイルメニツヒ ソシエテ アノニムＦｉｒｍｅｎｉｃｈ Ｓａ ポリ尿素マイクロカプセルの製造方法
US9022069B2 (en) 2013-03-15 2015-05-05 Mac Valves, Inc. Solenoid operated valve with constant bleed port
CN103331133B (zh) * 2013-06-07 2015-06-24 深圳大学 一种以聚脲为壁材的环氧微胶囊及其制备方法
GB2509430B (en) * 2014-03-26 2016-09-14 Rotam Agrochem Int Co Ltd Herbicidal composition, a method for its preparation and the use thereof

Also Published As

Publication number Publication date
WO2018019894A1 (en) 2018-02-01
CN109477041A (zh) 2019-03-15
US11471397B2 (en) 2022-10-18
JP7416620B2 (ja) 2024-01-17
JP2019524434A (ja) 2019-09-05
US20190269603A1 (en) 2019-09-05
MX2019000609A (es) 2019-07-04
EP3491110A1 (en) 2019-06-05

Similar Documents

Publication Publication Date Title
SG11201811706RA (en) Process for the preparation of microcapsules
SG11201811708QA (en) Process for the preparation of microcapsules
SG11201811035TA (en) Core-composite shell microcapsules
SG11201811151PA (en) Extracellular vesicle comprising a fusion protein having fc binding capacity
SG11201901972YA (en) Hybrid microcapsules
SG11201809912UA (en) Hybrid carriers for nucleic acid cargo
SG11201909949XA (en) Targeted immunotolerance
SG11201901700UA (en) Biaryl compounds useful as immunomodulators
SG11201903417PA (en) Ringing gel composition
SG11201811431VA (en) Multispecific antibodies against cd40 and cd137
SG11201808566WA (en) Polymorphic form of n-{6-(2-hydroxypropan-2-yl)-2-[2-(methylsulphonyl)ethyl]-2h-indazol-5-yl}-6-(trifluoromethyl)pyridine-2-carboxamide
SG11201807913XA (en) Stabilized soluble pre-fusion rsv f proteins
SG11201807809XA (en) A transient commensal microorganism for improving gut health
SG11201809830WA (en) Selective reduction of cysteine-engineered antibodies
SG11201907604UA (en) Crystalline forms of the 4-pyrimidinesulfamide derivative aprocitentan
SG11201808686VA (en) Synthesis of indazoles
SG11201810429UA (en) Anti-cd19 antibody formulations
SG11201902531QA (en) Liquid pharmaceutical composition
SG11201903061YA (en) Combination treatments comprising administration of imidazopyrazinones
SG11201805001UA (en) Method of treating influenza a
SG11201809594WA (en) Nicotine particles and compositions
SG11201810078PA (en) Stabilized pre-fusion rsv f proteins
SG11201805149XA (en) Compositions comprising 15-hepe and methods of using the same
SG11201903145TA (en) Pharmaceutical complex formulation comprising amlodipine, losartan and chlorthalidone
SG11201903770UA (en) Combination treatments comprising imidazopyrazinones for the treatment of psychiatric and/or cognitive disorders