SG11201810551PA - Measurement system and method for characterizing tissue - Google Patents

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property MD 1101111 0 DOI HIM 011101 0 01111111111 1111111111111111111111111111 Organization International Bureau (10) International Publication Number (43) International Publication Date ......0\" WO 2018/000104 Al 04 January 2018 (04.01.2018) W I PO I PCT (51) International Patent Classification: EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, A61B 5/01 (2006.01) A61B 5/00 (2006.01) HU, ID, IL, IN, IR, IS, JP, KE, KG, KN, KP, KR, KZ, LA, (21) International Application Number: LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, PCT/CH2016/000099 MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, (22) International Filing Date: SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, 30 June 2016 (30.06.2016) UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (25) Filing Language: English (84) Designated States (unless otherwise indicated, for every (26) Publication Language: English kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (71) Applicant: OPUS NEOI GMBH [CH/CH]; Riedtlistrasse UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, 27, 8006 Ziirich (CH). TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FL FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, (72) Inventors: BONMARIN, Mathias; Schiirbungert 47, 8057 MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, Ziirich (CH). VON SCHULTHESS, Patrick; Winterthur-TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, erstrasse 69, 8006 Ziirich (CH). FAHRNI, Simon; Josef- KM, ML, MR, NE, SN, TD, TG). strasse 178a, 8005 Ziirich (CH). GRUNDLER, Tobias; Oberdorfstrasse 2c, 8370 Sirnach (CH). KUNZLI, Pascal; Published: Winikerstrasse 4, 8610 Uster (CH). REINKE, Nils; Ter- — with international search report (Art. 21(3)) rassenweg 30, 8408 Winterthur (CH). (74) Agent: E. BLUM & CO. AG; Vorderberg 11, 8044 Ziirich = (CH). (81) Designated States (unless otherwise indicated, for every _ kind of national protection available): AE, AG, AL, AM, — AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, _ CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, = = (54) Title: MEASUREMENT SYSTEM AND METHOD FOR CHARACTERIZING TISSUE (57) : A measurement system (1) for characterizing sample tissue = 13 .11 (4; 4a, 4b) in a non-invasive way comprises a stimulation device (3; 3a, .----- - 3b; 3a, 3c) for thermal stimulation of the sample tissue (4; 4a, 4b), a tem- - perature sensor (2; 2a, 2b) for capturing at least one temperature profile of — _ the tissue to the temper- sample (4) and a computing unit (11) connected = _ ature sensor (2; 2a, 2b) for processing data delivered by the temperature _ = -- 1 L '1 sensor (2; 2a, 2b). Thermal radiation radiated by the sample tissue (4; 4a, 4b) from at least a measurement area (5) is detectable as a result of the thermal stimulation by the temperature sensor (2; 2a, 2b) during the ther- mal stimulation of the sample tissue (4; 4a, 4b). The stimulation device [ = = 6 \ = 11 4 / 1 \ comprises a temperature regulating body (3; 3a, 3b; 3a, 3c) which is in continuous contact with the sample tissue (4; 4a, 4b) in a contact area (6) during an entire measurement period. During a measurement period the temperature regulating body (3; 3a, 3b; 3a, 3c) has a different temperature than the sample tissue (4; 4a, 4b). ba 7r Il __1 © ,-.... 4b 11 ei Fia_ 1 C