SG11201901986SA - Process for the manufacture of a solid pharmaceutical adminstration form - Google Patents

Process for the manufacture of a solid pharmaceutical adminstration form

Info

Publication number
SG11201901986SA
SG11201901986SA SG11201901986SA SG11201901986SA SG11201901986SA SG 11201901986S A SG11201901986S A SG 11201901986SA SG 11201901986S A SG11201901986S A SG 11201901986SA SG 11201901986S A SG11201901986S A SG 11201901986SA SG 11201901986S A SG11201901986S A SG 11201901986SA
Authority
SG
Singapore
Prior art keywords
international
solid pharmaceutical
darmstadt
strasse
english
Prior art date
Application number
SG11201901986SA
Inventor
Stefan Schiller
Andrea Hanefeld
Gerhard Jonschker
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SG11201901986SA publication Critical patent/SG11201901986SA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/10—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of compressed tablets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/10—Processes of additive manufacturing
    • B29C64/165—Processes of additive manufacturing using a combination of solid and fluid materials, e.g. a powder selectively bound by a liquid binder, catalyst, inhibitor or energy absorber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/20—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B29C64/205—Means for applying layers
    • B29C64/209—Heads; Nozzles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/20—Apparatus for additive manufacturing; Details thereof or accessories therefor
    • B29C64/264—Arrangements for irradiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C64/00—Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
    • B29C64/30—Auxiliary operations or equipment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y10/00—Processes of additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y40/00—Auxiliary operations or equipment, e.g. for material handling
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y80/00—Products made by additive manufacturing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B33—ADDITIVE MANUFACTURING TECHNOLOGY
    • B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
    • B33Y30/00—Apparatus for additive manufacturing; Details thereof or accessories therefor

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 111111101111 0 1110101011111 011101 0 0111111111111111111111111111111111111110111111 Organization 0 International Bureau (10) International Publication Number (43) International Publication Date .....0\"\" WO 2018/046642 Al 15 March 2018 (15.03.2018) WI P0 I P C T (51) International Patent Classification: B29C 64/00 (2017.01) A61K 9/20 (2006.01) (21) International Application Number: PCT/EP2017/072551 (22) International Filing Date: 08 September 2017 (08.09.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 16188177.6 09 September 2016 (09.09.2016) EP (71) Applicant: MERCK PATENT GMBH [DE/DE]; Frank- furter Strasse 250, 64293 Darmstadt (DE). (72) Inventors: SCHILLER, Stefan; Wilhelm-Leuschn- er-Strasse 56, 64293 Darmstadt (DE). HANEFELD, Andrea; Odenwaldstrasse 7, 64297 Darmstadt (DE). JONSCHKER, Gerhard; Bertold-Brecht-Weg 55, 64646 Heppenheim (DE). Designated States (unless otherwise indicated, for every (81) = kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. = _ — = = = _ _ = Designated States (unless otherwise indicated, for every (84) = kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). = = — = = = = — = = Published: — with international search report (Art. 21(3)) Il ei ii- iv © (54) Title: PROCESS FOR THE MANUFACTURE OF A SOLID PHARMACEUTICAL ADMINSTRATION FORM --.... ,-1 (57) : The present invention relates to a process for the preparation of a solid pharmaceutical administration form using a 3D 0 printing process as well. The process is a printing process that allows the production of solid pharmaceutical administration forms in a \" flexible manner and in conformity with the high quality standards required for the production of pharmaceuticals.
SG11201901986SA 2016-09-09 2017-09-08 Process for the manufacture of a solid pharmaceutical adminstration form SG11201901986SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16188177 2016-09-09
PCT/EP2017/072551 WO2018046642A1 (en) 2016-09-09 2017-09-08 Process for the manufacture of a solid pharmaceutical adminstration form

Publications (1)

Publication Number Publication Date
SG11201901986SA true SG11201901986SA (en) 2019-04-29

Family

ID=56926030

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201901986SA SG11201901986SA (en) 2016-09-09 2017-09-08 Process for the manufacture of a solid pharmaceutical adminstration form

Country Status (14)

Country Link
US (2) US11229577B2 (en)
EP (2) EP3509815B1 (en)
JP (2) JP7023935B2 (en)
KR (1) KR20190050807A (en)
CN (1) CN109661305B (en)
AU (1) AU2017322186A1 (en)
BR (1) BR112019003437A2 (en)
CA (1) CA3036138A1 (en)
ES (1) ES2926490T3 (en)
IL (1) IL265239A (en)
MX (1) MX2019002238A (en)
RU (1) RU2019109633A (en)
SG (1) SG11201901986SA (en)
WO (1) WO2018046642A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102018107585B3 (en) * 2018-03-29 2019-03-28 Universität Rostock Device for producing 3D printed drug delivery systems with drug depots, and methods for manufacturing 3D printed drug delivery systems
CN112739331A (en) 2018-09-14 2021-04-30 默克专利股份有限公司 Process for preparing coated solid pharmaceutical dosage forms
EP3975987A1 (en) * 2019-05-31 2022-04-06 DiHeSys Digital Health Systems GmbH Pharmaceutical dosage forms and method for their production
CN114340596A (en) * 2019-05-31 2022-04-12 迪赫西斯数字健康系统有限公司 Additive method for 3D printing of active ingredient-containing articles
CN113244181B (en) * 2021-04-28 2023-05-26 浙江工业大学 Method for rapidly preparing tablets by adopting large-spot heating and melting formula powder
IL309660A (en) * 2021-07-08 2024-02-01 Merck Patent Gmbh Process for the manufacture of a solid pharmaceutical administration form
WO2023146533A1 (en) * 2022-01-28 2023-08-03 Hewlett-Packard Development Company, L.P. Three-dimensional printing
WO2023200954A1 (en) 2022-04-13 2023-10-19 Aprecia Pharmaceuticals LLC System and method for additive manufacturing using an omnidirectional magnetic movement apparatus

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US6176874B1 (en) * 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
BR0212951A (en) * 2001-09-28 2004-10-26 Mcneil Ppc Inc Composite Dosage Forms
DE602005027673D1 (en) * 2004-03-05 2011-06-09 Vegenics Pty Ltd MATERIALS AND METHODS FOR GROWTH FACTORY BONDING CONSTRUCTS
DE102004020452A1 (en) 2004-04-27 2005-12-01 Degussa Ag Method for producing three-dimensional objects by means of electromagnetic radiation and applying an absorber by inkjet method
FR2875409B1 (en) * 2004-09-17 2010-05-07 Sanofi Aventis PHARMACEUTICAL COMPOSITION COMPRISING A SOLID POLYMERIC MATRIX DISPERSION COMPRISING A CONTINUOUS PHASE OF POLYDEXTROSE AND A CONTINUOUS PHASE OF A POLYMER OTHER THAN POLYDEXTROSE
EP2664444B1 (en) 2007-07-25 2018-03-28 Stratasys Ltd. Solid freeform fabrication using a plurality of modeling materials
EP3045148B1 (en) 2009-12-30 2018-11-14 Synthes GmbH Intergrated multi-material implants and methods of manufacture
EP3747632A1 (en) 2010-10-27 2020-12-09 Rize Inc. Process and apparatus for fabrication of three-dimensional objects
CN109908355B (en) 2013-03-15 2022-11-15 阿普雷奇亚制药有限责任公司 Fast dispersing dosage form comprising levetiracetam
US9339489B2 (en) 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
WO2014188079A1 (en) 2013-05-23 2014-11-27 Åbo Akademi University Printed dosage forms
CN103393543A (en) * 2013-08-02 2013-11-20 魏雪纹 Method using 3D printing technology to prepare dropping pills
EP3122393B1 (en) * 2014-03-25 2020-04-22 Orthopaedic Innovation Centre Inc. Selective laser sintering process (sls) for producing antibiotic-eluting medical implants
US11771655B2 (en) * 2014-09-08 2023-10-03 University Of Central Lancashire Solid dosage form production
JP6782241B2 (en) * 2015-01-12 2020-11-11 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ Multi-layer skin replacement products, and how to make and use them
CN105770899A (en) * 2016-03-07 2016-07-20 北京诺康达医药科技有限公司 Quick release agent of large-dose medicine and preparation method of quick release agent
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Also Published As

Publication number Publication date
JP7365438B2 (en) 2023-10-19
EP3509815A1 (en) 2019-07-17
EP4091796A1 (en) 2022-11-23
CA3036138A1 (en) 2018-03-15
CN109661305B (en) 2022-10-28
US20190192383A1 (en) 2019-06-27
RU2019109633A3 (en) 2020-11-17
BR112019003437A2 (en) 2019-05-21
AU2017322186A1 (en) 2019-05-02
CN109661305A (en) 2019-04-19
RU2019109633A (en) 2020-10-09
JP7023935B2 (en) 2022-02-22
JP2019532921A (en) 2019-11-14
US20220110830A1 (en) 2022-04-14
US11229577B2 (en) 2022-01-25
IL265239A (en) 2019-05-30
WO2018046642A1 (en) 2018-03-15
ES2926490T3 (en) 2022-10-26
JP2022066223A (en) 2022-04-28
EP3509815B1 (en) 2022-06-08
KR20190050807A (en) 2019-05-13
MX2019002238A (en) 2019-06-24

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