SG11201810465RA - Compositions and methods related to engineered fc constructs - Google Patents

Compositions and methods related to engineered fc constructs

Info

Publication number
SG11201810465RA
SG11201810465RA SG11201810465RA SG11201810465RA SG11201810465RA SG 11201810465R A SG11201810465R A SG 11201810465RA SG 11201810465R A SG11201810465R A SG 11201810465RA SG 11201810465R A SG11201810465R A SG 11201810465RA SG 11201810465R A SG11201810465R A SG 11201810465RA
Authority
SG
Singapore
Prior art keywords
massachusetts
international
street
rule
constructs
Prior art date
Application number
SG11201810465RA
Other languages
English (en)
Inventor
Jonathan C Lansing
Carlos J Bosques
Daniel Ortiz
Original Assignee
Momenta Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Momenta Pharmaceuticals Inc filed Critical Momenta Pharmaceuticals Inc
Publication of SG11201810465RA publication Critical patent/SG11201810465RA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/524—CH2 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/53—Hinge
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
SG11201810465RA 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs SG11201810465RA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662340322P 2016-05-23 2016-05-23
US201762443451P 2017-01-06 2017-01-06
PCT/US2017/034087 WO2017205436A1 (en) 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs

Publications (1)

Publication Number Publication Date
SG11201810465RA true SG11201810465RA (en) 2018-12-28

Family

ID=60412547

Family Applications (3)

Application Number Title Priority Date Filing Date
SG11201810465RA SG11201810465RA (en) 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs
SG10202011624SA SG10202011624SA (en) 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs
SG11201810466PA SG11201810466PA (en) 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG10202011624SA SG10202011624SA (en) 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs
SG11201810466PA SG11201810466PA (en) 2016-05-23 2017-05-23 Compositions and methods related to engineered fc constructs

Country Status (14)

Country Link
US (4) US11623964B2 (es)
EP (2) EP3484514B1 (es)
JP (4) JP2019519527A (es)
KR (3) KR102590061B1 (es)
CN (4) CN109789203B (es)
AU (2) AU2017272109B2 (es)
BR (2) BR112018074032A2 (es)
CA (2) CA3025306A1 (es)
DK (1) DK3484514T3 (es)
ES (1) ES2973251T3 (es)
IL (3) IL309293A (es)
PL (1) PL3484514T3 (es)
SG (3) SG11201810465RA (es)
WO (2) WO2017205436A1 (es)

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AU2019302662A1 (en) * 2018-07-11 2021-02-25 Momenta Pharmaceuticals, Inc. Compositions and methods related to engineered Fc-antigen binding domain constructs targeted to CCR4
BR112021000416A2 (pt) * 2018-07-11 2021-04-06 Momenta Pharmaceuticals, Inc. Composições e métodos relacionados a construtos do domínio de ligação fc-antígeno manipulado direcionado a cd38
WO2020014486A1 (en) * 2018-07-11 2020-01-16 Momenta Pharmaceuticals, Inc. Compositions and methods related to engineered fc-antigen binding domain constructs
CN112996910A (zh) * 2018-07-11 2021-06-18 动量制药公司 与靶向PD-L1的工程化Fc-抗原结合结构域构建体有关的组合物和方法
AU2019300020A1 (en) * 2018-07-11 2021-02-18 Momenta Pharmaceuticals, Inc. Compositions and methods related to engineered Fc-antigen binding domain constructs
BR112021000415A2 (pt) * 2018-07-11 2021-04-06 Momenta Pharmaceuticals, Inc. Composições e métodos relacionados a construtos do domínio de ligação fc-antígeno manipulados
US20210284717A1 (en) * 2018-07-11 2021-09-16 Momenta Pharmaceuticals, Inc. Compositions and methods related to engineered fc-antigen binding domain constructs
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Also Published As

Publication number Publication date
US20210221917A1 (en) 2021-07-22
CN109789203B (zh) 2022-08-05
AU2017272109B2 (en) 2024-07-25
JP2022095685A (ja) 2022-06-28
KR20190026684A (ko) 2019-03-13
US11623964B2 (en) 2023-04-11
KR102590061B1 (ko) 2023-10-18
KR102635635B1 (ko) 2024-02-14
KR102462084B1 (ko) 2022-11-02
CN109789203A (zh) 2019-05-21
AU2017272109A1 (en) 2019-01-17
IL263211B1 (en) 2023-05-01
JP7045333B6 (ja) 2022-05-06
AU2017272111A1 (en) 2019-01-17
JP7295301B2 (ja) 2023-06-20
US20240067757A1 (en) 2024-02-29
EP3464376A4 (en) 2020-03-18
CN116063540A (zh) 2023-05-05
IL263211A (en) 2018-12-31
JP2019519528A (ja) 2019-07-11
AU2017272111B2 (en) 2024-05-16
CA3025306A1 (en) 2017-11-30
PL3484514T3 (pl) 2024-04-29
IL263211B2 (en) 2023-09-01
IL263213A (en) 2018-12-31
BR112018074056A2 (pt) 2019-03-06
EP3484514A4 (en) 2020-08-12
US20190284305A1 (en) 2019-09-19
IL309293A (en) 2024-02-01
BR112018074032A2 (pt) 2019-02-26
SG11201810466PA (en) 2018-12-28
KR20220151025A (ko) 2022-11-11
CA3025310A1 (en) 2017-11-30
IL263213B1 (en) 2024-01-01
DK3484514T3 (da) 2024-01-29
EP3464376A1 (en) 2019-04-10
CN109963869A (zh) 2019-07-02
CN118206639A (zh) 2024-06-18
EP3484514B1 (en) 2023-12-06
JP2019519527A (ja) 2019-07-11
IL263213B2 (en) 2024-05-01
SG10202011624SA (en) 2021-01-28
JP7045333B2 (ja) 2022-03-31
WO2017205436A1 (en) 2017-11-30
ES2973251T3 (es) 2024-06-19
JP2022068176A (ja) 2022-05-09
KR20190021255A (ko) 2019-03-05
US11155640B2 (en) 2021-10-26
WO2017205434A1 (en) 2017-11-30
US20220049019A1 (en) 2022-02-17
EP3484514A1 (en) 2019-05-22

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