SG11201809474TA - Compositions and methods for bioengineered tissues - Google Patents

Compositions and methods for bioengineered tissues

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Publication number
SG11201809474TA
SG11201809474TA SG11201809474TA SG11201809474TA SG11201809474TA SG 11201809474T A SG11201809474T A SG 11201809474TA SG 11201809474T A SG11201809474T A SG 11201809474TA SG 11201809474T A SG11201809474T A SG 11201809474TA SG 11201809474T A SG11201809474T A SG 11201809474TA
Authority
SG
Singapore
Prior art keywords
international
north carolina
north
chapel hill
chapel
Prior art date
Application number
SG11201809474TA
Inventor
Ariel Dawn Hanson
Mitsuo Yamauchi
Eliane Lucie Wauthier
Timothy Anh-Hieu Dinh
Praveen SETHUPATHY
Lola M Reid
Original Assignee
Univ North Carolina Chapel Hill
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Publication date
Application filed by Univ North Carolina Chapel Hill filed Critical Univ North Carolina Chapel Hill
Publication of SG11201809474TA publication Critical patent/SG11201809474TA/en

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • C12N5/0671—Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
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    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
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    • A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
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Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization MUNIIIIIMUMINHOHMEHIMMEMIN International Bureau (10) International Publication Number (43) International Publication Date ....0\". WO 2017/196668 Al 16 November 2017 (16.11.2017) WIPO I PCT (51) International Patent Classification: more Road, Chapel Hill, North Carolina 27514 (US). C12N 5/00 (2006.01) C12N 5/071 (2010.01) DINH, Timothy Anh-Hieu; 210 Ridge Trail, Chapel Hill, A61L 27/24 (2006.01) C12N 5/09 (2010.01) North Carolina 27516 (US). SETHUPATHY, Praveen; A61L 27/36 (2006.01) C12N 7/00 (2006.01) 512 Rollesby Court, Hillsborough, North Carolina 27278 (21) International Application Number: (US). REID, Lola M.; 3621 Sweeten Creek Road, Chapel PCT/US2017/031320 Hill, North Carolina 27514 (US). (22) International Filing Date: (74) Agent: VILLACORTA, Gilberto M. et al.; FOLEY & LARDNER LLP, 3000 K Street N.W., Suite 600, Washing- 05 May 2017 (05.05.2017) ton, District of Columbia 20007-5109 (US). (25) Filing Language: English (81) Designated States (unless otherwise indicated, for every (26) Publication Language: English kind of national protection available): AE, AG, AL, AM, (30) Priority Data: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, 62/335,013 11 May 2016 (11.05.2016) US CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, 15/586,061 03 May 2017 (03.05.2017) US DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, (71) Applicant: THE UNIVERSITY OF NORTH CAROLI- KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, NA AT CHAPEL HILL [US/US]; Office of Commer- MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, cialization and Economic Development, 100 Europa Drive, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, Suite 430, Chapel Hill, North Carolina 27517 (US). SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, — TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. — (72) Inventors: HANSON, Ariel Dawn; 55 Hall Ave., Apt. = 3, Sommerville, Massachusetts 02144 (US). YAMAUCHI, (84) Designated States (unless otherwise indicated, for every Mitsuo; 208 Silver Creek Trail, Chapel Hill, North Car- kind of regional protection available): ARIPO (BW, GH, olina 27514 (US). WAUTHIER, Eliane Lucie; 720 Ken- GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, = = (54) Title: COMPOSITIONS EE EE EE 2000- 1800- - 1600- 1400- = 1200- 1000- = 800- _ g 600- = = 1 4 AND , t METHODS FOR BIOENGINEERED TISSUES , i lt 1 1 IlfAii IMFRESH 0.,,,,..P_., 4 ,. FIG IA TISSUE IE titiltifattttikttil BIOiAATRIX SCAFFOLD = GROWTH FACTORS = = — ,-1 'i FIG. 18 FIE IC GC ,tD ,D ,tD t:T ,-1 IN N (57) : The present disclosure positions employed in generation ' FIG. ID provides methods for producing bioengineered thereof. FIG. IE tissue along apparatus and other relevant com- [Continued on next page] WO 2017/196668 Al MIDEDIM1111011111111111111111111111111111111111111111111111011110111110111111111111 UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3))
SG11201809474TA 2016-05-11 2017-05-05 Compositions and methods for bioengineered tissues SG11201809474TA (en)

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CN109415690A (en) 2019-03-01
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AU2017264583A1 (en) 2018-12-06
BR112018072724A2 (en) 2019-02-19
RU2018142263A3 (en) 2020-08-07
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US20170369849A1 (en) 2017-12-28
IL262564A (en) 2018-12-31
KR20190008541A (en) 2019-01-24
JP2023055732A (en) 2023-04-18
CA3022526A1 (en) 2017-11-16
PH12018502303A1 (en) 2019-04-29
US20200080061A1 (en) 2020-03-12
EP3455343A1 (en) 2019-03-20

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