SG11201805787YA - Photonic superlattice-based devices and compositions for use in luminescent imaging, and methods of using the same - Google Patents

Photonic superlattice-based devices and compositions for use in luminescent imaging, and methods of using the same

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Publication number
SG11201805787YA
SG11201805787YA SG11201805787YA SG11201805787YA SG11201805787YA SG 11201805787Y A SG11201805787Y A SG 11201805787YA SG 11201805787Y A SG11201805787Y A SG 11201805787YA SG 11201805787Y A SG11201805787Y A SG 11201805787YA SG 11201805787Y A SG11201805787Y A SG 11201805787YA
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Singapore
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international
wavelength
go1n
rule
san diego
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SG11201805787YA
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Dietrich Dehlinger
Cheng Zhong
Juraj Topolancik
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Illumina Inc
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Publication of SG11201805787YA publication Critical patent/SG11201805787YA/en

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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
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    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide
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    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
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    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
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    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
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    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
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Abstract

310 Detection Circuit 312 321 322 321 321 322 (a) FIG.3 330 1 1 1 1 1 1 1 1 i A i 313 A l l e 2 314 311 300 \" 1 / (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2017/165703 Al 28 September 2017 (28.09.2017) WIPO I PCT 111111111111110111011111111111010111110 011111111100111011111011111111111110111111 W O 20 171657 / 03 Al (51) International Patent Classification: GO1N 21/64 (2006.01) GO1N 21/03 (2006.01) GO1N 21/77 (2006.01) GO1N 21/25 (2006.01) BOIL 3/00 (2006.01) (21) International Application Number: PCT/US2017/023900 (22) International Filing Date: 23 March 2017 (23.03.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/312,704 24 March 2016 (24.03.2016) US (71) Applicant: ILLUMINA, INC. [AE/US]; 5200 Illumina Way, San Diego, CA 92122 (US). (72) Inventors: DEHLINGER, Dietrich; 5200 Illumina Way, San Diego, CA 92122 (US). ZHONG, Cheng, Frank; 5200 Illumina Way, San Diego, CA 92122 (US). TO- POLANCIK, Juraj; 5200 Illumina Way, San Diego, CA 92122 (US). (74) Agent: FULLER, Michael, L.; Knobbe, Martens, Olson & Bear, LLP, 2040 Main Street, 14th Floor, Irvine, CA 92614 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). [Continued on next page] (54) Title: PHOTONIC SUPERLATTICE-BASED DEVICES AND COMPOSITIONS FOR USE IN LUMINESCENT IMAGING, = AND METHODS OF USING THE SAME (57) : Under one aspect, a device (300) is provided for use in luminescent imaging. The device (300) can include a photon- ic superlattice (310) including a first material, the first material having a first refractive index. The first material can include first and second major surfaces (311, 312) and first and second pluralities of features (313, 314) defined through at least one of the first and second major surfaces (311, 312), the features of the first plurality (313) differing in at least one characteristic from the features of the second plurality (314). The photonic superlattice (310) can support propagation of a first wavelength (ki) and a second wavelength (k2) approximately at a first angle out of the photonic superlattice (310), the first and second wavelengths (k 1 , k 2 ) being separated from one another by a first non-propagating wavelength that does not selectively propagate at the first angle out of the photonic superlattice (310). The device further can include a second material having a second refractive index that is different than the first refractive index. The second material can be disposed within, between, or over the first and second pluralities of features (313, 314) and can include first and second luminophores (321, 322). The device (300) further can include a first optical component (330) disposed over one of the first and second major surfaces (311, 312) of the first material. The first optical component (330) can [Continued on next page] WO 2017/165703 Al MIDEDIMOMOIDEIR010130HIONMEHMODEVOIMIE Declarations under Rule 4.17: as to applicant's entitlement to apply for and be granted a patent (Rule 4.17(ii)) as to the applicant's entitlement to claim the priority of the earlier application (Rule 4.17(iii)) Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h)) receive luminescence emitted by the first luminophore (321) at the first wavelength (k i ) approximately at the first angle, and can receive luminescence emitted by the second luminophore (322) at the second wavelength (?2) approximately at the first angle.
SG11201805787YA 2016-03-24 2017-03-23 Photonic superlattice-based devices and compositions for use in luminescent imaging, and methods of using the same SG11201805787YA (en)

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US201662312704P 2016-03-24 2016-03-24
PCT/US2017/023900 WO2017165703A1 (en) 2016-03-24 2017-03-23 Photonic superlattice-based devices and compositions for use in luminescent imaging, and methods of using the same

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