SG11201804714XA - Electrode integration into organs on chip devices - Google Patents

Electrode integration into organs on chip devices

Info

Publication number
SG11201804714XA
SG11201804714XA SG11201804714XA SG11201804714XA SG11201804714XA SG 11201804714X A SG11201804714X A SG 11201804714XA SG 11201804714X A SG11201804714X A SG 11201804714XA SG 11201804714X A SG11201804714X A SG 11201804714XA SG 11201804714X A SG11201804714X A SG 11201804714XA
Authority
SG
Singapore
Prior art keywords
international
iii
microchannel
rule
opened
Prior art date
Application number
SG11201804714XA
Other languages
English (en)
Inventor
Olivier Henry
Der Meer Andries Van
Donald Ingber
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of SG11201804714XA publication Critical patent/SG11201804714XA/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/305—Electrodes, e.g. test electrodes; Half-cells optically transparent or photoresponsive electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B81—MICROSTRUCTURAL TECHNOLOGY
    • B81C—PROCESSES OR APPARATUS SPECIALLY ADAPTED FOR THE MANUFACTURE OR TREATMENT OF MICROSTRUCTURAL DEVICES OR SYSTEMS
    • B81C3/00—Assembling of devices or systems from individually processed components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/12—Specific details about manufacturing devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Dispersion Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Electrochemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Electrotherapy Devices (AREA)
  • Prostheses (AREA)
SG11201804714XA 2015-12-16 2016-12-16 Electrode integration into organs on chip devices SG11201804714XA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562268454P 2015-12-16 2015-12-16
US201662297659P 2016-02-19 2016-02-19
PCT/US2016/067294 WO2017106727A1 (fr) 2015-12-16 2016-12-16 Intégration d'électrode dans des organes sur des dispositifs à puce

Publications (1)

Publication Number Publication Date
SG11201804714XA true SG11201804714XA (en) 2018-07-30

Family

ID=59057687

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201804714XA SG11201804714XA (en) 2015-12-16 2016-12-16 Electrode integration into organs on chip devices

Country Status (4)

Country Link
US (1) US20190025240A1 (fr)
GB (1) GB2561775A (fr)
SG (1) SG11201804714XA (fr)
WO (1) WO2017106727A1 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018224829B2 (en) * 2017-02-27 2022-11-24 President And Fellows Of Harvard College Integrated multi-electrode array and trans-endothelial electrical resistance in organ-on-a-chip microsystems
CN107629958B (zh) * 2017-08-08 2020-07-14 浙江理工大学 一种三维石墨烯界面的微流控芯片及其制备方法
CN107475072B (zh) * 2017-08-24 2020-12-11 浙江理工大学 基于三维石墨烯界面电极的细胞动态特性监测系统及方法
EP3678780A1 (fr) 2017-09-06 2020-07-15 The Charles Stark Draper Laboratory, Inc. Système et procédé de distribution de matériau biologique à assistance par électroporation
JP6892965B2 (ja) * 2018-02-26 2021-06-23 富士フイルム株式会社 流路デバイス
JP2019190888A (ja) * 2018-04-19 2019-10-31 ティーイーアイソリューションズ株式会社 流体チップ及び分析装置
EP3783349A4 (fr) * 2018-04-19 2022-01-19 TEI Solutions Inc. Puce fluidique et dispositif d'analyse
CN109096740B (zh) * 2018-07-20 2021-09-17 山东一诺威聚氨酯股份有限公司 抗菌抗静电tpu薄膜材料及其制备方法
CN109852542B (zh) * 2018-12-18 2020-09-04 北京化工大学 一种用于单细胞阻抗流式检测的微流控芯片及其加工方法
JP7316063B2 (ja) * 2019-03-01 2023-07-27 株式会社Ｓｃｒｅｅｎホールディングス 検査用デバイス
RU200073U1 (ru) * 2020-05-24 2020-10-05 Федеральное государственное автономное образовательное учреждение высшего образования "Национальный исследовательский университет "Высшая школа экономики" (НИУ ВШЭ) Устройство для измерения трансэпителиального электрического сопротивления барьерных клеток млекопитающих
JP2023123989A (ja) * 2022-02-25 2023-09-06 株式会社Ｓｃｒｅｅｎホールディングス 流路デバイス

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007021741A2 (fr) * 2005-08-10 2007-02-22 President And Fellows Of Harvard College Films electriquement conducteurs et semi-conducteurs
US9084546B2 (en) * 2005-08-31 2015-07-21 The Regents Of The University Of Michigan Co-electrodeposited hydrogel-conducting polymer electrodes for biomedical applications
US20070176629A1 (en) * 2005-11-28 2007-08-02 Electronics And Telecommunications Research Institute Molecular electronic device having organic conducting electrode as protective layer
US8647861B2 (en) * 2008-07-16 2014-02-11 Children's Medical Center Corporation Organ mimic device with microchannels and methods of use and manufacturing thereof
US20120211373A1 (en) * 2011-02-22 2012-08-23 The Regents Of The University Of Michigan Microfluidic system for measuring cell barrier function
WO2013184556A1 (fr) * 2012-06-05 2013-12-12 President And Fellows Of Harvard College Revêtements optiques ultraminces et dispositifs et procédés d'utilisation de revêtements optiques ultraminces
US9006845B2 (en) * 2013-01-16 2015-04-14 Infineon Technologies, A.G. MEMS device with polymer layer, system of a MEMS device with a polymer layer, method of making a MEMS device with a polymer layer
CN105794322B (zh) * 2013-12-06 2018-04-17 夏普株式会社 发光体基板、及其制造方法

Also Published As

Publication number Publication date
US20190025240A1 (en) 2019-01-24
GB201811613D0 (en) 2018-08-29
GB2561775A (en) 2018-10-24
WO2017106727A1 (fr) 2017-06-22

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